Zobrazeno 1 - 10
of 236
pro vyhledávání: '"non-functioning pituitary adenomas"'
Publikováno v:
Discover Oncology, Vol 15, Iss 1, Pp 1-19 (2024)
Abstract Purpose Non-functioning pituitary adenomas (NFPAs) are a group of these neoplasms originated from the adenohypophyse and do not show evidence of hormonal oversecretion. However, different genes and lncRNAs have been found to be dysregulated
Externí odkaz:
https://doaj.org/article/d55465a4506244da862606f8eff356df
Autor:
Nuria Valdés, Ana Romero, Estrella Diego, María Calatayud, Cristina Lamas, Marta Araujo-Castro, Cristina Álvarez-Escolá, José A. Díaz, Victoria Alcázar, Julia Sastre, Rosa Martínez, Josep Oriola, Miguel Paja, Paula Sánchez-Sobrino, Isabel Salinas, José María Recio-Córdova, Elena Navarro, María Dolores Chiara, Luis Castaño, Anna Casterás
Publikováno v:
Frontiers in Endocrinology, Vol 15 (2024)
IntroductionHistorically, Multiple Endocrine Neoplasia type 1 (MEN1)-related pituitary adenomas (PAs) were considered more aggressive and treatment-resistant than sporadic PAs. However, recent studies suggest similarities in their behavior. This stud
Externí odkaz:
https://doaj.org/article/0351ddc654c04674a2cd4f7d787be618
Autor:
Joan Gil, Montserrat Marques-Pamies, Elena Valassi, Guillermo Serra, Isabel Salinas, Gemma Xifra, Paula Casano-Sancho, Cristina Carrato, Betina Biagetti, Gemma Sesmilo, Jennifer Marcos-Ruiz, Helena Rodriguez-Lloveras, Anna Rueda-Pujol, Anna Aulinas, Alberto Blanco, Cristina Hostalot, Andreu Simó-Servat, Fernando Muñoz, Marta Rico, Javier Ibáñez-Domínguez, Esteban Cordero, Susan M. Webb, Mireia Jordà, Manel Puig-Domingo
Publikováno v:
Frontiers in Endocrinology, Vol 14 (2023)
IntroductionDifferent medical therapies have been developed for pituitary adenomas. However, Non-Functioning Pituitary Neuroendocrine Tumors (NF-PitNET) have shown little response to them. Furthermore, epithelial-mesenchymal transition (EMT) has been
Externí odkaz:
https://doaj.org/article/e5015b10f8ca4660a7bad11a7a2d25e9
Publikováno v:
Journal of Pathology and Translational Medicine, Vol 56, Iss 1, Pp 22-31 (2022)
Background Pituitary tumor transforming gene 1 (PTTG1), paired-like homeodomain 2 (PITX2), and galectin-3 have been widely studied as predictive biomarkers for various tumors and are involved in tumorigenesis and tumor progression. We evaluated the u
Externí odkaz:
https://doaj.org/article/2dc4c833f03c43cb9a9738ac3ee6b5d4
Akademický článek
Tento výsledek nelze pro nepřihlášené uživatele zobrazit.
K zobrazení výsledku je třeba se přihlásit.
K zobrazení výsledku je třeba se přihlásit.
Autor:
Wenxiu Zhao, Xiaobin Jiang, Karrin Weisenthal, Jun Ma, Erin M. Botticelli, Yunli Zhou, E. Tessa Hedley-Whyte, Baiyao Wang, Brooke Swearingen, Roy J. Soberman, Anne Klibanski, Xun Zhang
Publikováno v:
Frontiers in Oncology, Vol 12 (2022)
Epigenetic modification of chromatin is involved in non-malignant pituitary neoplasia by causing abnormal expression of tumor suppressors and oncogenes. These changes are potentially reversible, suggesting the possibility of targeting tumor cells by
Externí odkaz:
https://doaj.org/article/a51b38507b564d47a8b6de4809019a77
Autor:
Wenli Chen, Mengqi Wang, Chengbin Duan, Shun Yao, Haosen Jiao, Zongming Wang, Bin Hu, Zhigang Mao, Yonghong Zhu, Haijun Wang
Publikováno v:
Frontiers in Endocrinology, Vol 12 (2021)
BackgroundCurrently, it is difficult to estimate the possibility of recurrence of nonfunctioning pituitary adenomas (NFPAs). Markers such as Ki-67 or transcription factors rely on postoperative pathology, while few indices can be used for preoperativ
Externí odkaz:
https://doaj.org/article/40f9f180bbc34c9580b532d7ec88b4ec
Autor:
Ashutosh Rai, Liza Das, Kanchan K. Mukherjee, Sivashanmugam Dhandapani, Manjul Tripathi, Chirag Kamal Ahuja, Bishan Dass Radotra, Pinaki Dutta
Publikováno v:
Frontiers in Endocrinology, Vol 12 (2021)
PurposeNon-functioning pituitary adenomas (NFPAs) exhibit high recurrence rates after surgery. However, the determinants of recurrence are inconsistent in the available literature. The present study sought to investigate the association between nucle
Externí odkaz:
https://doaj.org/article/20489828f10a4ec0ae45291ef22f0016
Publikováno v:
Mìžnarodnij Endokrinologìčnij Žurnal, Vol 15, Iss 2, Pp 106-110 (2019)
Background. Nowadays, a search for diagnostically significant markers of aggressiveness of nonfunctioning pituitary adenomas remains relevant for further prognosis in the postoperative period. Nonfunctioning pituitary adenomas without pituitary h
Externí odkaz:
https://doaj.org/article/0306a9b98a0244e4a59e6bb2c99287c0
Publikováno v:
Data in Brief, Vol 33, Iss , Pp 106452- (2020)
Expression profiles of gonadal steroid receptor variants have been reportedly associated with malignancy in breast and prostate cancers [1,2]. However, such associations with pituitary tumors remain unclear. Therefore, the expression levels of the wi
Externí odkaz:
https://doaj.org/article/81c6dd6b8024415b94de0dbc0eaf8159