Zobrazeno 1 - 10
of 561
pro vyhledávání: '"non-apoptotic"'
Publikováno v:
Acta Pharmaceutica Sinica B, Vol 14, Iss 7, Pp 2815-2853 (2024)
Regulated cell death (RCD) is a controlled form of cell death orchestrated by one or more cascading signaling pathways, making it amenable to pharmacological intervention. RCD subroutines can be categorized as apoptotic or non-apoptotic and play esse
Externí odkaz:
https://doaj.org/article/0881ed82ae084982ab8caa3190444a8b
Publikováno v:
Annals of Medicine, Vol 56, Iss 1 (2024)
Background Cancer is characterized by its ability to resist cell death, and emerging evidence suggests a potential correlation between non-apoptotic regulated cell death (RCD), tumor progression, and therapy response. However, the prognostic signific
Externí odkaz:
https://doaj.org/article/96720b7d17c94b5a926e1284016c0514
Autor:
Sudershana Nair, Nicholas E Baker
Publikováno v:
eLife, Vol 12 (2024)
Many cell fate decisions are determined transcriptionally. Accordingly, some fate specification is prevented by Inhibitor of DNA-binding (Id) proteins that interfere with DNA binding by master regulatory transcription factors. We show that the Drosop
Externí odkaz:
https://doaj.org/article/9ac920143de8498a85c89794e8b48706
Publikováno v:
Cells, Vol 13, Iss 21, p 1814 (2024)
The mechanisms of CD95 (Fas/APO-1)-mediated extrinsic apoptotic pathway in cancer cells have been extensively studied. The majority of human cells express CD95, but not all these cells can induce extrinsic apoptosis. Accumulating evidence has shown t
Externí odkaz:
https://doaj.org/article/39758be2964d4d7092580e63d902023f
Autor:
Jiaan Lu, Ru He, Yang Liu, Jinghan Zhang, Heng Xu, Tianchi Zhang, Li Chen, Guanhu Yang, Jun Zhang, Jie Liu, Hao Chi
Publikováno v:
Frontiers in Cell and Developmental Biology, Vol 12 (2024)
Cancer remains a significant global challenge, with escalating incidence rates and a substantial burden on healthcare systems worldwide. Herein, we present an in-depth exploration of the intricate interplay between cancer cell death pathways and tumo
Externí odkaz:
https://doaj.org/article/4a5ff8a5af404909b308bc1b7c5de582
Publikováno v:
Heliyon, Vol 10, Iss 10, Pp e31342- (2024)
Background: Breast cancer (BC), the most common cancer among women globally, has been shown by numerous studies to significantly involve non-apoptotic regulatory cell death (RCD) in its pathogenesis and progression. Methods: We obtained the RNA seque
Externí odkaz:
https://doaj.org/article/f1eadfcf23574a838e6f175d772eb9ef
Publikováno v:
Heliyon, Vol 10, Iss 5, Pp e27162- (2024)
Individuals diagnosed with head and neck squamous cell carcinoma (HNSCC) experience a significant occurrence rate and are susceptible to premature spreading, resulting in a bleak outlook. Therapeutic approaches, such as chemotherapy, targeted therapy
Externí odkaz:
https://doaj.org/article/9f392153d986472b861fee0e6552b99d
Autor:
Yimin Dai, Shuang Zhou, Lin Qiao, Zhao Peng, Jiuliang Zhao, Dong Xu, Chanyuan Wu, Mengtao Li, Xiaofeng Zeng, Qian Wang
Publikováno v:
Frontiers in Endocrinology, Vol 14 (2023)
Diabetes mellitus (DM) is a chronic metabolic disorder that affects multiple organs and systems, including the pulmonary system. Pulmonary dysfunction in DM patients has been observed and studied for years, but the underlying mechanisms have not been
Externí odkaz:
https://doaj.org/article/8af1ea9ee1094a569a6f6582082caee4
Autor:
Zigui Chen, Dandan Zheng, Ziren Lin, Chunyuan Zhang, Cheng Wei, Xiandong Deng, Peng Yan, Chuanhua Zheng, Chuanliu Lan, Chengjian Qin, Xuanlei Wei, Deling Qin, Yongfang Wu, Jun Peng, Changfeng Miao, Liuxue Lu, Ying Xia, Qisheng Luo
Publikováno v:
Frontiers in Immunology, Vol 14 (2023)
IntroductionGliomas have emerged as the predominant brain tumor type in recent decades, yet the exploration of non-apoptotic cell death regulated by the pan-optosome complex, known as pan-apoptosis, remains largely unexplored in this context. This st
Externí odkaz:
https://doaj.org/article/ad1403da0b624d46bb7ee66798b5efae
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