Zobrazeno 1 - 10
of 7 728
pro vyhledávání: '"nkg2d"'
Autor:
Mohamad K. Hammoud, Celina Meena, Raimund Dietze, Nathalie Hoffmann, Witold Szymanski, Florian Finkernagel, Andrea Nist, Thorsten Stiewe, Johannes Graumann, Elke Pogge von Strandmann, Rolf Müller
Publikováno v:
Cell Communication and Signaling, Vol 22, Iss 1, Pp 1-23 (2024)
Abstract Background High levels of the polyunsaturated fatty acid arachidonic acid (AA) within the ovarian carcinoma (OC) microenvironment correlate with reduced relapse-free survival. Furthermore, OC progression is tied to compromised immunosurveill
Externí odkaz:
https://doaj.org/article/b5b59f79e7714241a2f9d27ed2f57ac0
Autor:
Hitoshi Toyoda, Atsuo Kuramasu, Masahiro Hosonuma, Masakazu Murayama, Yoichiro Narikawa, Junya Isobe, Yuta Baba, Kohei Tajima, Eiji Funayama, Midori Shida, Yuki Maruyama, Aya Sasaki, Yuya Hirasawa, Toshiaki Tsurui, Hirotsugu Ariizumi, Tomoyuki Ishiguro, Risako Suzuki, Sei Kobayashi, Atsushi Horiike, Noriko Hida, Takehiko Sambe, Koji Nobe, Satoshi Wada, Hitome Kobayashi, Mayumi Tsuji, Shinichi Kobayashi, Takuya Tsunoda, Yoshifumi Kudo, Yuji Kiuchi, Kiyoshi Yoshimura
Publikováno v:
Scientific Reports, Vol 14, Iss 1, Pp 1-12 (2024)
Abstract Natural killer group 2 member D ligands (NKG2DLs) are expressed as stress response proteins in cancer cells. NKG2DLs induce immune cell activation or tumor escape responses, depending on their expression. Human pancreatic cancer cells, PANC-
Externí odkaz:
https://doaj.org/article/9cc18d13b98e4eae855bec63d4c5642c
Autor:
Airi Ishibashi, Yue Li, Yuuta Hisatomi, Noriko Ohta, Yuko Uegaki, Atsushi Tanemura, Riuko Ohashi, Koji Kitamura, Kotaro Saga, Yasuhide Yoshimura, Satoko Inubushi, Kyoso Ishida, Sadahiro Iwabuchi, Shinichi Hashimoto, Eiji Kiyohara, Hideo Yagita, Yasufumi Kaneda, Keisuke Nimura
Publikováno v:
Molecular Therapy: Oncology, Vol 32, Iss 4, Pp 200893- (2024)
The tumor-infiltrating lymphocyte (TIL) is a crucial factor in controlling tumor growth. A therapeutic method activating TIL is desired for treating patients with metastatic tumors. Here, we show that treating a local tumor with a combination therapy
Externí odkaz:
https://doaj.org/article/951e81fafd1f410bb0dbccb39e7651a0
Autor:
Qiusui Mai, Bailin He, Shikai Deng, Qing Zeng, Yanwen Xu, Cong Wang, Yunyi Pang, Sheng Zhang, Jinfeng Li, Jinfeng Zeng, Liqin Huang, Yongshui Fu, Chengyao Li, Tingting Li, Xiaojun Xu, Ling Zhang
Publikováno v:
Experimental Hematology & Oncology, Vol 13, Iss 1, Pp 1-18 (2024)
Abstract Epstein-Barr virus (EBV) related post-transplant lymphoproliferative disorder (EBV-PTLD) is a life-threatening complication after hematopoietic stem cell transplantation (HSCT) or solid organ transplantation (SOT), for which no standard ther
Externí odkaz:
https://doaj.org/article/4f77cc45aa3f49358bfb6eacd3798041
Publikováno v:
mAbs, Vol 16, Iss 1 (2024)
Natural killer (NK) cells are effector cells of the innate immune system that distinguish between healthy and abnormal cells through activating and inhibitory receptor signaling. NKG2D, a homodimeric activating receptor expressed on NK cells, recogni
Externí odkaz:
https://doaj.org/article/226c08477f9a4a3aac1f4727a2361136
Autor:
Roberto Littera, Stefano Mocci, Davide Argiolas, Letizia Littarru, Sara Lai, Maurizio Melis, Celeste Sanna, Caterina Mereu, Michela Lorrai, Alessia Mascia, Andrea Angioi, Giacomo Mascia, Valeria Matta, Nicola Lepori, Matteo Floris, Cristina Manieli, Paola Bianco, Daniela Onnis, Stefania Rassu, Silvia Deidda, Mauro Giovanni Carta, Erika Giuressi, Andrea Perra, Luchino Chessa, Sabrina Giglio, Antonello Pani
Publikováno v:
Frontiers in Immunology, Vol 15 (2024)
BackgroundAntibody-mediated rejection is a significant cause of kidney transplant failure. Recent studies have shown that the MHC class I MICA gene influences the transplantation outcome. However, the role of the primary MICA receptor, NKG2D, has yet
Externí odkaz:
https://doaj.org/article/6ed1fe38c60c43d99e3e2af024d4866c
Akademický článek
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Autor:
Alvaro Morales-Molina, Miguel Angel Rodriguez-Milla, Patricia Garcia-Rodriguez, Laura Hidalgo, Ramon Alemany, Javier Garcia-Castro
Publikováno v:
Molecular Therapy: Oncology, Vol 32, Iss 3, Pp 200863- (2024)
Oncolytic viruses often face challenges in achieving optimal antitumor immunity as standalone therapies. The penton base RGD-integrin interactions play a significant role in wild-type adenovirus-induced innate immune responses. To modify these respon
Externí odkaz:
https://doaj.org/article/f889f634fb8d45d19137a418f077a9bb
Autor:
Mohamed A Selim, Reda A. Suef, Ebrahim Saied, Mostafa A. Abdel-Maksoud, Saeedah Musaed Almutairi, Mohammed Aufy, Adel A. Mousa, Mohamed T. M. Mansour, Mohamed M. S. Farag
Publikováno v:
Frontiers in Immunology, Vol 15 (2024)
BackgroundThe relationship between chronic hepatitis B (CHB) infection and natural killer (NK) cell dysfunction is well-established, but the specific role of HBV viral antigens in driving NK cell impairment in patients with CHB remains unclear. This
Externí odkaz:
https://doaj.org/article/1e6a6c9e51824783b44f684359d89dbe
Autor:
Jordi Pfeifer Serrahima, Katrin Schoenfeld, Ines Kühnel, Julia Harwardt, Arturo Macarrón Palacios, Maren Prüfer, Margareta Kolaric, Pranav Oberoi, Harald Kolmar, Winfried S. Wels
Publikováno v:
Frontiers in Immunology, Vol 15 (2024)
NKG2D is an activating receptor expressed by natural killer (NK) cells and other cytotoxic lymphocytes that plays a pivotal role in the elimination of neoplastic cells through recognition of different stress-induced cell surface ligands (NKG2DL). To
Externí odkaz:
https://doaj.org/article/af94d95b092647eebbb988a5701ced76