Zobrazeno 1 - 10
of 433
pro vyhledávání: '"nk receptors"'
Publikováno v:
Clinical and Translational Medicine, Vol 14, Iss 11, Pp n/a-n/a (2024)
Abstract Natural killer cell engagers (NKCEs) are a specialised subset of antibodies capable of simultaneously targeting endogenous NK cells and tumour cells, generating precise and effective cytolytic responses against cancer. This review systematic
Externí odkaz:
https://doaj.org/article/6f278796564e484fae63b2415e2bfbcc
Autor:
Jasper Nörenberg, Péter Vida, Isabell Bösmeier, Barbara Forró, Anna Nörenberg, Ágnes Buda, Diana Simon, Szabina Erdő-Bonyár, Pál Jáksó, Kálmán Kovács, Éva Mikó, Tímea Berki, Emese Mezősi, Alíz Barakonyi
Publikováno v:
Frontiers in Immunology, Vol 15 (2024)
During pregnancy, the maternal immune system must allow and support the growth of the developing placenta while maintaining the integrity of the mother’s body. The trophoblast’s unique HLA signature is a key factor in this physiological process.
Externí odkaz:
https://doaj.org/article/a82fd79f160a4f6d8599f62c3456e42a
Autor:
Sajad A. Bhat, Mahmoud Elnaggar, Thomas J. Hall, Gillian P. McHugo, Cian Reid, David E. MacHugh, Kieran G. Meade
Publikováno v:
Frontiers in Immunology, Vol 14 (2023)
Bovine tuberculosis (bTB), caused by infection with Mycobacterium bovis, continues to cause significant issues for the global agriculture industry as well as for human health. An incomplete understanding of the host immune response contributes to the
Externí odkaz:
https://doaj.org/article/12e73de268d8406192d5e21d3f30bf8f
Autor:
Siqin Duan, Shuwen Liu
Publikováno v:
Frontiers in Immunology, Vol 13 (2022)
Combined antiretroviral therapy (cART) can inhibit the replication of human immunodeficiency virus type 1 (HIV-1) and reduce viral loads in the peripheral blood to undetectable levels. However, the presence of latent HIV-1 reservoirs prevents complet
Externí odkaz:
https://doaj.org/article/fa1ae2d229104f47acc967187354f505
Akademický článek
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Autor:
Yuhan Sun, Alexander James Sedgwick, Md Abdullah-Al-Kamran Khan, Yaseelan Palarasah, Stefano Mangiola, Alexander David Barrow
Publikováno v:
Frontiers in Immunology, Vol 12 (2021)
Activation of natural killer (NK) cell function is regulated by cytokines, such as IL-2, and secreted factors upregulated in the tumor microenvironment, such as platelet-derived growth factor D (PDGF-DD). In order to elucidate a clinical role for the
Externí odkaz:
https://doaj.org/article/9a25b716f78e484a8ead390e5f420cf3
Autor:
Leonardo M. Amorim, Danillo G. Augusto, Neda Nemat-Gorgani, Gonzalo Montero-Martin, Wesley M. Marin, Hengameh Shams, Ravi Dandekar, Stacy Caillier, Peter Parham, Marcelo A. Fernández-Viña, Jorge R. Oksenberg, Paul J. Norman, Jill A. Hollenbach
Publikováno v:
Frontiers in Immunology, Vol 12 (2021)
The KIR (killer-cell immunoglobulin-like receptor) region is characterized by structural variation and high sequence similarity among genes, imposing technical difficulties for analysis. We undertook the most comprehensive study to date of KIR geneti
Externí odkaz:
https://doaj.org/article/aa5a1107c343415581b1d8b8a30fec56
Akademický článek
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Inhibitory Receptors and Checkpoints in Human NK Cells, Implications for the Immunotherapy of Cancer
Autor:
Simona Sivori, Mariella Della Chiesa, Simona Carlomagno, Linda Quatrini, Enrico Munari, Paola Vacca, Nicola Tumino, Francesca Romana Mariotti, Maria Cristina Mingari, Daniela Pende, Lorenzo Moretta
Publikováno v:
Frontiers in Immunology, Vol 11 (2020)
The highly destructive mechanisms by which the immune system faces microbial infections is under the control of a series of inhibitory receptors. While most of these receptors prevent unwanted/excessive responses of individual effector cells, others
Externí odkaz:
https://doaj.org/article/c1f40604c39a473b9c81825e3389f6ce
Autor:
Lutz Walter, Ronald Bontrop
Publikováno v:
Frontiers in Immunology, Vol 11 (2020)
Externí odkaz:
https://doaj.org/article/a7988270d71e4d64a393a7fba276f749