Zobrazeno 1 - 10
of 945
pro vyhledávání: '"nitroalkene"'
Autor:
Fei Chang, Camilla Gunderstofte, Nicole Colussi, Mareena Pitts, Sonia R. Salvatore, Anne L. Thielke, Lucia Turell, Beatriz Alvarez, Raphaela Goldbach-Mansky, Luis Villacorta, Christian K. Holm, Francisco J. Schopfer, Anne Louise Hansen
Publikováno v:
Redox Biology, Vol 74, Iss , Pp 103202- (2024)
Stimulator of Interferon Genes (STING) is essential for the inflammatory response to cytosolic DNA. Despite that aberrant activation of STING is linked to an increasing number of inflammatory diseases, the development of inhibitors has been challengi
Externí odkaz:
https://doaj.org/article/cf3a9eefd90d46eca97eb23c61fe9d7d
Publikováno v:
Beilstein Journal of Organic Chemistry, Vol 19, Iss 1, Pp 892-900 (2023)
Although nitrocyclopropanedicarboxylic acid esters are widely used in organic syntheses, nitrocyclopropanes with an acyl group have not yet been synthesized. When adducts of β-nitrostyrene and 1,3-dicarbonyl compounds are treated with (diacetoxyiodo
Externí odkaz:
https://doaj.org/article/66962a4f33af442f9a2417feb5904753
Autor:
Agnieszka Fryźlewicz, Aleksandra Olszewska, Karolina Zawadzińska, Przemysław Woliński, Karolina Kula, Agnieszka Kącka-Zych, Agnieszka Łapczuk-Krygier, Radomir Jasiński
Publikováno v:
Organics, Vol 3, Iss 1, Pp 59-76 (2022)
We investigated the reactivity of different substituted nitrylimine-type three atom components (TACs) in [3+2] cycloaddition (32CAs) reactions with electrophilically activated nitroethenes within molecular electron density theory (MEDT). In parallel
Externí odkaz:
https://doaj.org/article/906316ae24e64bcfb475ad4177bb0eb8
Akademický článek
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Akademický článek
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Publikováno v:
Molecules, Vol 28, Iss 14, p 5289 (2023)
The molecular mechanism of the Diels–Alder reaction with the participation of cyclopentadiene and isopropyl 3-nitroprop-2-enate was examined based on wb97xd/6-311+G(d) (PCM) quantum chemical calculations. It was found that the type of mechanism for
Externí odkaz:
https://doaj.org/article/dd7e0650e3a240129860a3cf3c4ddad6
Autor:
Adolf Koudelka, Veronika Cechova, Mauricio Rojas, Nilay Mitash, Anna Bondonese, Claudette St. Croix, Mark A. Ross, Bruce A. Freeman
Publikováno v:
Redox Biology, Vol 50, Iss , Pp 102226- (2022)
Tissue fibrosis occurs in response to dysregulated metabolism, pro-inflammatory signaling and tissue repair reactions. For example, lungs exposed to environmental toxins, cancer therapies, chronic inflammation and other stimuli manifest a phenotypic
Externí odkaz:
https://doaj.org/article/35581b9bda244c64a72292eaba451e09
Publikováno v:
Beilstein Journal of Organic Chemistry, Vol 16, Iss 1, Pp 1830-1836 (2020)
β-Nitrostyrenes underwent a Diels–Alder reaction with Danishefsky’s diene to afford cyclohexenes together with the corresponding hydrolyzed products, 3-arylated-5-methoxy-4-nitrocyclohexanones. When the reaction was conducted in the presence of
Externí odkaz:
https://doaj.org/article/9d3ab46efb4243fb977d04b7323e9b0a
Autor:
Nadine Hellmuth, Camilla Brat, Omar Awad, Sven George, Astrid Kahnt, Tom Bauer, Hai Phong Huynh Phuoc, Dieter Steinhilber, Carlo Angioni, Mohamed Hassan, Katharina J. Hock, Georg Manolikakes, Kai Zacharowski, Jessica Roos, Thorsten J. Maier
Publikováno v:
Frontiers in Pharmacology, Vol 12 (2021)
Endogenous nitro-fatty acids (NFA) are potent electrophilic lipid mediators that exert biological effects in vitro and in vivo via selective covalent modification of thiol-containing target proteins. The cytoprotective, anti-inflammatory, and anti-tu
Externí odkaz:
https://doaj.org/article/c657c0db8df64313911506d3687aff34
Autor:
Ming-Yu Fang, Kuan-Hsun Huang, Wei-Ju Tu, Yi-Ting Chen, Pei-Yun Pan, Wan-Chi Hsiao, Yi-Yu Ke, Lun K. Tsou, Mingzi M. Zhang
Publikováno v:
Redox Biology, Vol 46, Iss , Pp 102126- (2021)
Nitro-fatty acids are a class of endogenous electrophilic lipid mediators with anti-inflammatory and cytoprotective effects in a wide range of inflammatory and fibrotic disease models. While these beneficial biological effects of nitro-fatty acids ar
Externí odkaz:
https://doaj.org/article/07ddefb9cb444550933900ccaf1114fd