Zobrazeno 1 - 10
of 163
pro vyhledávání: '"niemann–pick type c1"'
Autor:
Lucía de Dios-Blázquez, Ana Laura Cano-Argüelles, Ricardo Pérez-Sánchez, María González-Sánchez, Ana Oleaga
Publikováno v:
Ticks and Tick-Borne Diseases, Vol 15, Iss 6, Pp 102382- (2024)
Cholesterol is a molecule vital for tick physiology, but ticks cannot synthesize it and rely on dietary cholesterol. Therefore, tick proteins involved in cholesterol absorption and transport, such as the Niemann-Pick type C1 domain-containing (NPC1)
Externí odkaz:
https://doaj.org/article/65cd9ffdc09e4da39f0962588cbf6999
Publikováno v:
European Journal of Cell Biology, Vol 103, Iss 1, Pp 151382- (2024)
The ongoing phagocytic activity of macrophages necessitates an extraordinary capacity to digest and resolve incoming material. While the initial steps leading to the formation of a terminal phagolysosome are well studied, much less is known about the
Externí odkaz:
https://doaj.org/article/f07f20a17f20420595cd112d07adbcb7
Publikováno v:
Machine Learning: Science and Technology, Vol 5, Iss 4, p 045004 (2024)
Supervised machine learning (SML) techniques have been developed since the 1960s. Most of their applications were oriented towards developing models capable of predicting numerical values or categorical output based on a set of input variables (input
Externí odkaz:
https://doaj.org/article/3c10834ba4e342e086c70d1ae6507ecd
Akademický článek
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Publikováno v:
Frontiers in Aging Neuroscience, Vol 14 (2022)
Palmitoylation is a dynamic process that regulates the activity of the modified proteins. Retinal pigment epithelial (RPE) cells play pivotal roles in the visual cycle and maintaining healthy photoreceptor cells. Dysfunctional RPE cells are often ass
Externí odkaz:
https://doaj.org/article/1b4b0ab7692f45d3956a530e6aa46267
Akademický článek
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Publikováno v:
Indian Journal of Pathology and Microbiology, Vol 63, Iss 2, Pp 312-314 (2020)
Sea-blue histiocytes in bone marrow can be associated with a number of conditions and have indeed often been reported in Niemann-Pick diseases, mostly in Niemann-Pick type B, but also Niemann-Pick type C. Rarely, it was reported to be related to a pr
Externí odkaz:
https://doaj.org/article/9b2d1189f3ca49f099861ade473bbb7e
Autor:
Yingjie Zhou, Satoe Takahashi, Kazuaki Homma, Chongwen Duan, Jason Zheng, Mary Ann Cheatham, Jing Zheng
Publikováno v:
Acta Neuropathologica Communications, Vol 6, Iss 1, Pp 1-12 (2018)
Abstract Niemann-Pick Type C1 (NPC1) disease is a fatal neurovisceral disorder caused by dysfunction of NPC1 protein, which plays a role in intracellular cholesterol trafficking. The cholesterol-chelating agent, 2-hydroxypropyl-β-cyclodextrin (HPβC
Externí odkaz:
https://doaj.org/article/cd51f04e632e4b018b7cb3826e3f8b63
Akademický článek
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Publikováno v:
Data in Brief, Vol 12, Iss C, Pp 123-131 (2017)
Data presented in this article demonstrate the generation and characterization of two novel Niemann-Pick disease Type C1 (NPC1) patient-specific induced pluripotent stem cell (iPSC) lines, related to the research article Trilck et al. (Diversity of G
Externí odkaz:
https://doaj.org/article/159ce8fffd284fee8029a6c3a3e5cf44