Zobrazeno 1 - 10
of 178
pro vyhledávání: '"nicotinamide adenine dinucleotide (NAD+)"'
Autor:
Wing-Hong Jonathan Ho, Maria B Marinova, Dave R Listijono, Michael J Bertoldo, Dulama Richani, Lynn-Jee Kim, Amelia Brown, Angelique H Riepsamen, Safaa Cabot, Emily R Frost, Sonia Bustamante, Ling Zhong, Kaisa Selesniemi, Derek Wong, Romanthi Madawala, Maria Marchante, Dale M Goss, Catherine Li, Toshiyuki Araki, David J Livingston, Nigel Turner, David A Sinclair, Kirsty A Walters, Hayden A Homer, Robert B Gilchrist, Lindsay E Wu
Publikováno v:
EMBO Molecular Medicine, Vol 16, Iss 10, Pp 2583-2618 (2024)
Abstract Chemotherapy induced ovarian failure and infertility is an important concern in female cancer patients of reproductive age or younger, and non-invasive, pharmacological approaches to maintain ovarian function are urgently needed. Given the r
Externí odkaz:
https://doaj.org/article/d790c5942525403bbb14e10daad41da9
Publikováno v:
MedComm, Vol 5, Iss 10, Pp n/a-n/a (2024)
Abstract Noninvasive pharmacological strategies like nicotinamide mononucleotide (NMN) supplementation can effectively address age‐related ovarian infertility by maintaining or enhancing oocyte quality and quantity. This study revealed that ovarian
Externí odkaz:
https://doaj.org/article/959cc543d5714dba8dd0c6ade3feb646
Publikováno v:
PeerJ, Vol 12, p e17833 (2024)
Background This study endeavored to develop a nicotinamide adenine dinucleotide (NAD+) metabolism-related biomarkers in gastric cancer (GC), which could provide a theoretical foundation for prognosis and therapy of GC patients. Methods In this study,
Externí odkaz:
https://doaj.org/article/4cf69da897294fb3823571b74b23998d
Publikováno v:
Cells, Vol 13, Iss 21, p 1799 (2024)
Nicotinamide adenine dinucleotide (NAD+) is indispensable for the regulation of biological metabolism. Previous studies have revealed its role in aging and degenerative diseases, while crucially showing that supplementation with NAD+ or its precursor
Externí odkaz:
https://doaj.org/article/6c93232ef1e44566bf13c9994f7f9b21
Publikováno v:
Frontiers in Pharmacology, Vol 15 (2024)
Metabolic syndrome (MetS) represents a constellation of metabolic abnormalities, typified by obesity, hypertension, hyperglycemia, and hyperlipidemia. It stems from intricate dysregulations in metabolic pathways governing energy and substrate metabol
Externí odkaz:
https://doaj.org/article/174fe159ae104101bb1879b600fae8ba
Autor:
Al-Hussein Ahmed Saqr, Can Kamali, Philipp Brunnbauer, Nils Haep, Pia Koch, Karl-Herbert Hillebrandt, Eriselda Keshi, Simon Moosburner, Raphael Mohr, Nathanael Raschzok, Johann Pratschke, Felix Krenzien
Publikováno v:
Frontiers in Medicine, Vol 10 (2024)
Nicotinamide adenine dinucleotide (NAD+), a coenzyme for more than 500 enzymes, plays a central role in energy production, metabolism, cellular signaling, and DNA repair. Until recently, NAD+ was primarily considered to be an intracellular molecule (
Externí odkaz:
https://doaj.org/article/f62e9aee36234b028fc99e7ac63e2fbb
Autor:
Jiankai Fang, Wangwang Chen, Pengbo Hou, Zhanhong Liu, Muqiu Zuo, Shisong Liu, Chao Feng, Yuyi Han, Peishan Li, Yufang Shi, Changshun Shao
Publikováno v:
Cell & Bioscience, Vol 13, Iss 1, Pp 1-15 (2023)
Abstract Nicotinamide adenine dinucleotide (NAD+) is a critical metabolite that acts as a cofactor in energy metabolism, and serves as a cosubstrate for non-redox NAD+-dependent enzymes, including sirtuins, CD38 and poly(ADP-ribose) polymerases. NAD+
Externí odkaz:
https://doaj.org/article/75f343314e69468d95934cd036a6b3d8
Publikováno v:
Metabolites, Vol 14, Iss 6, p 343 (2024)
The complex process of aging leads to a gradual deterioration in the function of cells, tissues, and the entire organism, thereby increasing the risk of disease and death. Nicotinamide N-methyltransferase (NNMT) has attracted attention as a potential
Externí odkaz:
https://doaj.org/article/a407e9f8b47f432ab57a14b8ad3a4cb6
Publikováno v:
Antioxidants, Vol 13, Iss 5, p 546 (2024)
Emerging data indicate that lung macrophages (LM) may provide a novel biomarker to classify disease endotypes in bronchopulmonary dysplasia (BPD), a form of infant chronic lung disease, and that augmentation of the LM phenotype may be a potential the
Externí odkaz:
https://doaj.org/article/f3ba5817649f44478be2ef2467c3502f
Publikováno v:
Frontiers in Oncology, Vol 13 (2023)
BackgroundNicotinamide adenine dinucleotide (NAD+) is vital for not only energy metabolism but also signaling pathways. A major source of NAD+ depletion is the activation of poly (ADP-ribose) polymerase (PARP) in response to DNA damage. We have previ
Externí odkaz:
https://doaj.org/article/663e5b9f2bb0408797b06fec4439c04e