Zobrazeno 1 - 10
of 562
pro vyhledávání: '"ngs (next generation sequencing)"'
Autor:
Shahrzad Manavi Nameghi
Publikováno v:
Endocrine and Metabolic Science, Vol 16, Iss , Pp 100193- (2024)
The pathophysiology of Type 2 Diabetes (T2D) is intricate, involving three main processes that lead to elevated glucose levels. Insulin resistance hinders glucose utilization in muscles, adipose tissue, and the liver. Additionally, pancreatic dysfunc
Externí odkaz:
https://doaj.org/article/d2cb188547304539a8ca15e3ccb4f6a8
Autor:
Daniela Carolina de Bastiani, Claudia Vallone Silva, Ana Paula Christoff, Giuliano Netto Flores Cruz, Leonardo Daniel Tavares, Luana Silva Rodrigues de Araújo, Bruno Martins Tomazini, Beatriz Arns, Filipe Teixeira Piastrelli, Alexandre Biasi Cavalcanti, Luiz Felipe Valter de Oliveira, Adriano Jose Pereira
Publikováno v:
Frontiers in Public Health, Vol 12 (2024)
IntroductionInfections acquired during healthcare setting stay pose significant public health threats. These infections are known as Healthcare-Associated Infections (HAI), mostly caused by pathogenic bacteria, which exhibit a wide range of antimicro
Externí odkaz:
https://doaj.org/article/61f8ed5d5e5c47d2863c1c95eee02dee
Autor:
Maxim Karagyaur, Alexandra Primak, Kirill Bozov, Dmitriy Sheleg, Mikhail Arbatsky, Stalik Dzhauari, Maria Illarionova, Ekaterina Semina, Larisa Samokhodskaya, Polina Klimovich, Arkadiy Velichko, Mikhail Drach, Ekaterina Sotskaya, Vladimir Popov, Kseniya Rubina, Mariia Parfenenko, Julia Makus, Boris Tsygankov, Vsevolod Tkachuk, Elena Neyfeld
Publikováno v:
Frontiers in Psychiatry, Vol 15 (2024)
IntroductionImpaired function of brain morphogenic genes is considered one of the predisposing factors for the manifestation of psychiatric and cognitive disorders, such as paranoid schizophrenia (SCZ) and major depressive disorder (MDD). Identificat
Externí odkaz:
https://doaj.org/article/5426d66842114c638bf97ce43cbfc3b0
Autor:
Stephanie Efthymiou, Wenyan Han, Muhammad Ilyas, Jun Li, Yichao Yu, Marcello Scala, Nancy T. Malintan, Nikoleta Vavouraki, Kshitij Mankad, Reza Maroofian, Clarissa Rocca, Vincenzo Salpietro, Shenela Lakhani, Eric J. Mallack, Timothy Blake Palculict, Hong Li, Guojun Zhang, Faisal Zafar, Nuzhat Rana, Noriko Takashima, Hayato Matsunaga, Claudia Manzoni, Pasquale Striano, Mark F. Lythgoe, Jun Aruga, Wei Lu, Henry Houlden
Publikováno v:
Frontiers in Molecular Neuroscience, Vol 17 (2024)
This study reports on biallelic homozygous and monoallelic de novo variants in SLITRK3 in three unrelated families presenting with epileptic encephalopathy associated with a broad neurological involvement characterized by microcephaly, intellectual d
Externí odkaz:
https://doaj.org/article/4c9fba0e92c64e6881b4e82760b9b3c3
Publikováno v:
Frontiers in Oncology, Vol 14 (2024)
Immune checkpoint blockade (ICB) has indeed transformed the outlook for many advanced-stage solid tumors, yet its effectiveness in hematological malignancies has been particularly limited, with success predominantly demonstrated in classical Hodgkin
Externí odkaz:
https://doaj.org/article/5bfc0f433de5436196b17ad772ffc159
Autor:
Ana Jiménez-Ubieto, Alejandro Martín-Muñoz, María Poza, Sara Dorado, Almudena García-Ortiz, Enrique Revilla, Pilar Sarandeses, Yanira Ruiz-Heredia, Tycho Baumann, Antonia Rodríguez, María Calbacho, Pilar Martínez Sánchez, José María Sánchez Pina, Alejandro Martín García-Sancho, Gloria Figaredo, Daniel Gil-Alós, Laura Rufián, Margarita Rodríguez, Laura Carneros, Carolina Martínez-Laperche, Mariana Bastos-Oreiro, Chongwu Wang, María-Teresa Cedena, Inmaculada Rapado, Paula de Toledo, Miguel Gallardo, Antonio Valeri, Rosa Ayala, Joaquín Martínez-López, Santiago Barrio
Publikováno v:
Frontiers in Immunology, Vol 14 (2024)
Externí odkaz:
https://doaj.org/article/6180b4e41d7e48c3aa85430dc0d50bae
Autor:
Frontiers Production Office
Publikováno v:
Frontiers in Immunology, Vol 15 (2024)
Externí odkaz:
https://doaj.org/article/f1941019d2414e97be8565c5de19db52
Autor:
Yan Xu, Mingming Zhao, Li Zhang, Tianyou Wang, Bo Wang, Yu Xue, Zhiying Xu, Wenyu Shao, Xiaojun Chen, Chao Wang
Publikováno v:
Frontiers in Oncology, Vol 13 (2023)
BackgroundThe molecular classification of endometrial cancer has previously been shown to be associated with clinical outcomes. However, there are insufficient data to support the routine use of molecular classification for the treatment of patients
Externí odkaz:
https://doaj.org/article/526ad8325bfd4d13a3bce7e9db556791
Publikováno v:
Frontiers in Oncology, Vol 13 (2023)
Externí odkaz:
https://doaj.org/article/f877df3f574d48bfb56ab3e342332fd8
Publikováno v:
Frontiers in Oncology, Vol 13 (2023)
Epidermal growth factor receptor (EGFR) is an established driver gene in non-small cell lung cancer (NSCLC) and the common Exon 19 del mutation (p.E746_A750 del) has exhibited remarkable responses for EGFR tyrosine kinase inhibitors (TKIs). However,
Externí odkaz:
https://doaj.org/article/e2771ad19aef4f69ae8931e7a58efddb