Zobrazeno 1 - 10
of 284
pro vyhledávání: '"new targets"'
Publikováno v:
Discover Oncology, Vol 15, Iss 1, Pp 1-25 (2024)
Abstract Background Neuroblastoma (NB) is the most common extracranial solid tumor in childhood and is closely related to the early development and differentiation of neuroendocrine (NE) cells. The disease is mainly represented by high-risk NB, which
Externí odkaz:
https://doaj.org/article/74481f7fd77d4afa8c9c6921071af013
Publikováno v:
Zhongliu Fangzhi Yanjiu, Vol 50, Iss 11, Pp 1139-1144 (2023)
Antibody-drug conjugates (ADCs) are novel drugs consisting of monoclonal antibodies targeting tumor-specific or tumor-associated antigens coupled with different numbers of payloads via linkers. ADCs have shown promising clinical benefits in the treat
Externí odkaz:
https://doaj.org/article/6f0b8bc7d5d448fc99a1267a105a7d3c
Akademický článek
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Autor:
Luisa M. Cardenas, Jasna E. Deluce, Shahrukh Khan, Omar Gulam, Saman Maleki Vareki, Ricardo Fernandes, Aly-Khan A. Lalani
Publikováno v:
Current Oncology, Vol 29, Iss 8, Pp 5426-5441 (2022)
While surgical resection has remained the mainstay of treatment in early-stage renal cell carcinoma (RCC), therapeutic options in the advanced setting have remarkably expanded over the last 20 years. Tyrosine kinase inhibitors targeting the vascular
Externí odkaz:
https://doaj.org/article/319c1185afaf477eb8b7c0ce6999da9f
Publikováno v:
Frontiers in Immunology, Vol 14 (2023)
Externí odkaz:
https://doaj.org/article/55a43ad5839f4bf79bb4208023242e61
Publikováno v:
Biomarker Research, Vol 9, Iss 1, Pp 1-18 (2021)
Abstract B-cell non-Hodgkin lymphoma (B-NHL) is a group of heterogeneous disease which remains incurable despite developments of standard chemotherapy regimens and new therapeutic agents in decades. Some individuals could have promising response to s
Externí odkaz:
https://doaj.org/article/21d9bbe196d24a20a3de464ab38bca29
Publikováno v:
Frontiers in Immunology, Vol 13 (2022)
Externí odkaz:
https://doaj.org/article/1a919f07cfda43bc9685bca540e62063
Autor:
Mehdi Valipour, Hamid Irannejad
Publikováno v:
Journal of Mazandaran University of Medical Sciences, Vol 29, Iss 172, Pp 188-206 (2019)
Epilepsy is a neurological condition characterized by recurrent seizures influencing about 1% of the worldwide population. Despite much progress in understanding the pathogenesis of epilepsy, the molecular basis of human epilepsy still remains unclea
Externí odkaz:
https://doaj.org/article/df433be6273849faaddff7fa2ba1a75a
Publikováno v:
Antibiotics, Vol 11, Iss 8, p 1109 (2022)
Many new antimicrobials are analogs of existing drugs, sharing the same targets and mechanisms of action. New antibiotic targets are critically needed to combat the growing threat of antimicrobial-resistant bacteria. Phage-related ribosomal proteases
Externí odkaz:
https://doaj.org/article/d5906344b8344f10a11660fab492b9a6
Publikováno v:
Frontiers in Pharmacology, Vol 12 (2021)
Externí odkaz:
https://doaj.org/article/d47d1f9baeef495aaa06a0633d878fc8