Zobrazeno 1 - 10
of 176
pro vyhledávání: '"new drug targets"'
Autor:
Wedad M. Nageeb, Nada AlHarbi, Amani A. Alrehaili, Shadi A. Zakai, Ahmed Elfadadny, Helal F. Hetta
Publikováno v:
Frontiers in Microbiology, Vol 14 (2023)
IntroductionAlthough carbapenemases are frequently reported in resistant A. baumannii clinical isolates, other chromosomally mediated elements of resistance that are considered essential are frequently underestimated. Having a wide substrate range, m
Externí odkaz:
https://doaj.org/article/594fc1d0988f4528b01b16e6710881e7
Autor:
Aura Temereanca, Simona Ruta
Publikováno v:
Frontiers in Microbiology, Vol 14 (2023)
The availability of combined antiretroviral therapy (cART) has revolutionized the course of HIV infection, suppressing HIV viremia, restoring the immune system, and improving the quality of life of HIV infected patients. However, the emergence of dru
Externí odkaz:
https://doaj.org/article/77f23e99b68a493587d5731a299daab9
Autor:
Zolty R
Publikováno v:
Journal of Experimental Pharmacology, Vol Volume 13, Pp 817-857 (2021)
Ronald Zolty Pulmonary Hypertension Program, University of Nebraska Medical Center, Lied Transplant Center, Omaha, NE, USACorrespondence: Ronald Zolty 982265 Nebraska Medical Center, Room 8712, Omaha, NE, 68198-2265 Tel +1 4025595591Fax +1 4025598355
Externí odkaz:
https://doaj.org/article/d7743112d6b944bc81427946f410f63f
Publikováno v:
Pathogens, Vol 12, Iss 2, p 333 (2023)
The rising burden of antimicrobial resistance and increasing infectious disease outbreaks, including the recent COVID-19 pandemic, has led to a growing demand for the development of natural products as a valuable source of leading medicinal compounds
Externí odkaz:
https://doaj.org/article/071d62ce69444d73b69ff488d1940922
Autor:
Gabriele Trespidi, Viola Camilla Scoffone, Giulia Barbieri, Giovanna Riccardi, Edda De Rossi, Silvia Buroni
Publikováno v:
Antibiotics, Vol 9, Iss 12, p 841 (2020)
The worldwide spread of antimicrobial resistance highlights the need of new druggable cellular targets. The increasing knowledge of bacterial cell division suggested the potentiality of this pathway as a pool of alternative drug targets, mainly based
Externí odkaz:
https://doaj.org/article/11e30e0b960448e8a33971bc52a67b41
Akademický článek
Tento výsledek nelze pro nepřihlášené uživatele zobrazit.
K zobrazení výsledku je třeba se přihlásit.
K zobrazení výsledku je třeba se přihlásit.
Autor:
Nicola Marchi, Qingyuan Fan, Chaitali Ghosh, Vincent Fazio, Francesca Bertolini, Giulia Betto, Ayush Batra, Erin Carlton, Imad Najm, Tiziana Granata, Damir Janigro
Publikováno v:
Neurobiology of Disease, Vol 33, Iss 2, Pp 171-181 (2009)
Status epilepticus (SE) is one of the most serious manifestations of epilepsy. Systemic inflammation and damage of blood-brain barrier (BBB) are etiologic cofactors in the pathogenesis of pilocarpine SE while acute osmotic disruption of the BBB is su
Externí odkaz:
https://doaj.org/article/dfae748cabe8464b89edc79194233004
Autor:
Lisa F. Dawson, Anna M. Seekatz, Dina Kao, Weng C Chan, Claudia C E R Moore-Gillon, Tanya Monaghan, Benjamin H. Mullish, Ammar Ahmed
Introduction: Clostridioides difficile infection (CDI) remains a worldwide clinical problem. Increased incidence of primary infection, occurrence of hypertoxigenic ribotypes, and more frequent occurrence of drug resistant, recurrent, and non-hospital
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::fdd26572c0b2f1fdb2564378dcfb9997
http://hdl.handle.net/10044/1/93047
http://hdl.handle.net/10044/1/93047
Akademický článek
Tento výsledek nelze pro nepřihlášené uživatele zobrazit.
K zobrazení výsledku je třeba se přihlásit.
K zobrazení výsledku je třeba se přihlásit.
Autor:
Ronald Zolty
Publikováno v:
Journal of Experimental Pharmacology
Pulmonary arterial hypertension (PAH) is a progressive and devastating disease characterized by pulmonary artery vasoconstriction and vascular remodeling leading to vascular rarefaction with elevation of pulmonary arterial pressures and pulmonary vas
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6fadbaa15ded518f03011bb0e1ad2b0c
https://pubmed.ncbi.nlm.nih.gov/34429666
https://pubmed.ncbi.nlm.nih.gov/34429666