Zobrazeno 1 - 10
of 8 759
pro vyhledávání: '"neutrophil elastase"'
Publikováno v:
Drug Design, Development and Therapy, Vol Volume 18, Pp 4449-4458 (2024)
Jie Wang,1 Yuanbo Wu,2 Meng Mao,3 Hailong Bing,1 Liwei Sun,1 Wei Xu,1 Wangli Tian,1 Zhengyuan Xia,4,5 Xiaogao Jin,1,6 Qinjun Chu1 1Department of Anesthesiology and Perioperative Medicine, Zhengzhou Central Hospital Affiliated to Zhengzhou University,
Externí odkaz:
https://doaj.org/article/14b1bb542bad4df898e1ecc0cc54b57a
Autor:
Yeonju Seo, Se Ik Kim, Sang Hoon Song, Jisoo G. Kim, Ja-Yoon Gu, Hye Won Jeon, Maria Lee, Hyun Kyung Kim
Publikováno v:
Translational Oncology, Vol 49, Iss , Pp 102072- (2024)
Objective: Neutrophils produce neutrophil extracellular traps (NETs) by releasing nuclear contents into the extracellular environment. NETs are associated with systemic inflammation and cancer development and progression. We aimed to investigate whet
Externí odkaz:
https://doaj.org/article/8a7b8066d8874bc7948d04f7a75a4d83
Autor:
Shuying Xu, Shumin Tan, Patricia Romanos, Jennifer L. Reedy, Yihan Zhang, Michael K. Mansour, Jatin M. Vyas, Joan Mecsas, Hongmei Mou, John M. Leong
Publikováno v:
mBio, Vol 15, Iss 9 (2024)
ABSTRACT Streptococcus pneumoniae (Sp), a leading cause of community-acquired pneumonia, can spread from the lung into the bloodstream to cause septicemia and meningitis, with a concomitant threefold increase in mortality. Limitations in vaccine effi
Externí odkaz:
https://doaj.org/article/ad03c385123a48d58ccc8fa1dd434f9d
Publikováno v:
Dermatologica Sinica, Vol 42, Iss 2, Pp 80-88 (2024)
Pemphigoid diseases (PDs) are a group of autoimmune blistering diseases, including bullous pemphigoid, epidermolysis bullosa acquisita, mucous membrane pemphigoid, linear immunoglobulin A disease, and other rare variants. These diseases are character
Externí odkaz:
https://doaj.org/article/537e81c4b0824bef86bd06112bc2cf61
Publikováno v:
Discover Oncology, Vol 15, Iss 1, Pp 1-13 (2024)
Abstract Neutrophil elastase (NE) is a proteolytic enzyme released extracellular during the formation of neutrophil extracellular traps (NETs) through degranulation. In addition to participating in the body's inflammatory response, NE also plays an i
Externí odkaz:
https://doaj.org/article/3df990ee4abf48a9aebdfa5a5c2c0437
Publikováno v:
The Ukrainian Biochemical Journal, Vol 96, Iss 2, Pp 27-37 (2024)
Nonalcoholic fatty liver disease (NAFLD), which can progress to nonalcoholic steatohepatitis (NASH), is a significant health concern affecting a substantial portion of the population. This study investigates the role of neutrophil extracellular traps
Externí odkaz:
https://doaj.org/article/8d647ad9bb064f11b5a9c7839abbe6fb
Publikováno v:
Heliyon, Vol 10, Iss 15, Pp e35470- (2024)
Resident physicians on long-term night shifts often face sleep deprivation, affecting the immune response, notably neutrophils, vital to innate defense mechanisms. Sleep-deprived residents exhibit altered neutrophil counts and reduced phagocytosis an
Externí odkaz:
https://doaj.org/article/3d9fe810c78f49f6a64e2852b57acb9e
Publikováno v:
Frontiers in Pharmacology, Vol 15 (2024)
Background: Alpha-1 antitrypsin deficiency (AATD) is a genetic condition resulting from mutations in the alpha-1 antitrypsin (AAT) protein, a major systemic antiproteinase, resulting in reduced/no release of AAT, disrupting the proteinase/antiprotein
Externí odkaz:
https://doaj.org/article/6f4233b5a72a4d90af2cf6faacf8a454
Publikováno v:
Mustansiriya Medical Journal, Vol 22, Iss 2, Pp 214-216 (2024)
Background: Hemophilia is an inherited bleeding disorder that could cause many complications one of them is hemarthrosis. Neutrophils are the predominant immune cells that infiltrate joints after hemorrhage. Tissue injury is often accompanied by the
Externí odkaz:
https://doaj.org/article/95aa909fdd2b4744a775756589fda510
Autor:
Lihong Wang, Zhoujunhao Zhou, Xinming Xu, Yue Li, Rui Zhang, Zhiyan Yu, Xinmei Huang, Shufei Zang, Tiange Sun
Publikováno v:
Reproductive Biology and Endocrinology, Vol 22, Iss 1, Pp 1-13 (2024)
Abstract Background Chronic inflammation plays a vital role in the development of gestational diabetes mellitus (GDM). Studies in mouse models show that neutrophil serine proteases (NSPs), neutrophil elastase (NE) and proteinase-3 (PR3) are important
Externí odkaz:
https://doaj.org/article/99b5ffee696f4cb58b8d1666a6de7e2a