Zobrazeno 1 - 10
of 370
pro vyhledávání: '"neutrophil dysfunction"'
Autor:
Carola Ledderose, Eleftheria-Angeliki Valsami, Mark Elevado, Qing Liu, Brennan Giva, Julian Curatolo, Joshua Delfin, Reem Abutabikh, Wolfgang G. Junger
Publikováno v:
Immunity & Ageing, Vol 21, Iss 1, Pp 1-16 (2024)
Abstract Background The function of polymorphonuclear neutrophils (PMNs) decreases with age, which results in infectious and inflammatory complications in older individuals. The underlying causes are not fully understood. ATP release and autocrine st
Externí odkaz:
https://doaj.org/article/a42dfe66f023464695a745dd11c12ea6
Publikováno v:
Frontiers in Pediatrics, Vol 12 (2024)
Staphylococcus aureus (S. aureus) is a significant human pathogen, in particular in patients with an underlying medical condition. It is equipped with a large variety of virulence factors enabling both colonization and invasive disease. The spectrum
Externí odkaz:
https://doaj.org/article/4c9445eaf1954707b98346814b5194e4
Akademický článek
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Publikováno v:
Frontiers in Endocrinology, Vol 14 (2023)
Glycogen storage type Ib (GSDIb) is a rare inborn error of metabolism caused by glucose-6-phosphate transporter (G6PT, SLC37A4) deficiency. G6PT defect results in excessive accumulation of glycogen and fat in the liver, kidney, and intestinal mucosa
Externí odkaz:
https://doaj.org/article/00ecc232b5124ebb95d50bdb0fe8773e
Publikováno v:
Archives of Medical Science, Vol 18, Iss 4, Pp 1095-1099 (2022)
Introduction Recently published case reports suggest the benefit of empagliflozin use in subjects with glycogen storage disease Ib (GSD Ib). Material and methods We present the clinical and laboratory data of 2 adult brothers with GSD Ib treated wit
Externí odkaz:
https://doaj.org/article/0c7a5444e7a048e5b8bad1401eb2b808
Publikováno v:
Orphanet Journal of Rare Diseases, Vol 17, Iss 1, Pp 1-7 (2022)
Abstract Background Glycogen storage disease type Ib (GSD Ib) is a severe disorder of carbohydrate metabolism due to bi-allelic variants in SLC37A4. It is associated with neutropaenia and neutrophil dysfunction, which has recently been attributed to
Externí odkaz:
https://doaj.org/article/94bc67c78c1041c4a315663946ec9e3b
Autor:
Zufit Hexner-Erlichman, Maria Veiga-da-Cunha, Yoav Zehavi, Zahava Vadasz, Adi D. Sabag, Sameh Tatour, Ronen Spiegel
Publikováno v:
Frontiers in Pediatrics, Vol 10 (2022)
BackgroundGlycogen storage disease type 1b (GSD1b) is an ultra-rare autosomal recessive disorder, caused by mutations in SLC37A4 gene. Affected patients present with episodes of fasting hypoglycemia and lactic acidosis, hepatomegaly, growth retardati
Externí odkaz:
https://doaj.org/article/9ddd4db544c94b418be2850a58e52445
Autor:
Rebecca Halligan, Fiona J. White, Bernd Schwahn, Karolina M. Stepien, Nazreen Kamarus Jaman, Mel McSweeney, Steve Kitchen, Joanna Gribben, Charlotte Dawson, Katherine Lewis, David Cregeen, Helen Mundy, Saikat Santra
Publikováno v:
JIMD Reports, Vol 59, Iss 1, Pp 52-59 (2021)
Abstract Glycogen storage disease type Ib (GSDIb) is characterized by hepatomegaly and fasting hypoglycaemia as well as neutropaenia and recurrent infections. We conducted a retrospective observational study on a cohort of patients with GSDIb across
Externí odkaz:
https://doaj.org/article/90f760d60ce44f528516665b5bb177a9
Autor:
Kunaal Makkar, Shallu Tomer, Nipun Verma, Sahaj Rathi, Sunil K Arora, Sunil Taneja, Ajay Duseja, Yogesh K Chawla, Radha K Dhiman
Publikováno v:
JGH Open, Vol 4, Iss 4, Pp 595-602 (2020)
Abstract Background and Aim Innate immune disarray is a key component in the development and progression of acute on chronic liver failure (ACLF) and predisposition to infections. We evaluated the neutrophil dysfunction and its impact on outcomes in
Externí odkaz:
https://doaj.org/article/1b0170c093864773bf30996be852a8fd
Autor:
Sarah C. Grünert, Roland Elling, Bärbel Maag, Saskia B. Wortmann, Terry G. J. Derks, Luciana Hannibal, Anke Schumann, Stefanie Rosenbaum-Fabian, Ute Spiekerkoetter
Publikováno v:
Orphanet Journal of Rare Diseases, Vol 15, Iss 1, Pp 1-8 (2020)
Abstract Background Glycogen storage disease type Ib (GSD Ib) is a rare inborn error of glycogen metabolism due to mutations in SLC37A4. Besides a severe form of fasting intolerance, the disorder is usually associated with neutropenia and neutrophil
Externí odkaz:
https://doaj.org/article/900557e41e514fa59d0d7f2d8ec7418c