Zobrazeno 1 - 10
of 242
pro vyhledávání: '"neurovascular dysfunction"'
Publikováno v:
Frontiers in Physiology, Vol 15 (2024)
While cardiovascular disease, cancer, and human immunodeficiency virus (HIV) mortality rates have decreased over the past 20 years, Alzheimer’s Disease (AD) deaths have risen by 145% since 2010. Despite significant research efforts, effective AD tr
Externí odkaz:
https://doaj.org/article/5c1431ffb7694ce883eb843c68ac6bea
Publikováno v:
Frontiers in Endocrinology, Vol 14 (2023)
BackgroundInteraction between retinal vascular endothelial cells and neurons plays a critical role in the pathogenesis of diabetic retinopathy (DR). This study aims to compare an in vitro model over a monoculture model to simulate the neurovascular c
Externí odkaz:
https://doaj.org/article/eb7ecea45ee5437d8a65fa6d0a5f2531
Publikováno v:
Frontiers in Pharmacology, Vol 14 (2023)
Externí odkaz:
https://doaj.org/article/105f6440dcc842cf8ed8f82e95f13bc1
Autor:
Iffah Nadiah Laili, Mohd Hamzah Mohd Nasir, Nurul Farhana Jufri, Farah Wahida Ibrahim, Asmah Hamid
Publikováno v:
Biomedicine & Pharmacotherapy, Vol 161, Iss , Pp 114501- (2023)
Lysosome is a primary degradative organelle and is crucial in cellular homeostasis. A reduction in its function due to ageing has been associated with the development of Alzheimer's disease (AD), a common neurodegenerative disorder characterised by t
Externí odkaz:
https://doaj.org/article/120c777c04c0450dbe3d6527a03d0585
Autor:
Pengren Luo, Lin Li, Jiashang Huang, Deqiang Mao, Silong Lou, Jian Ruan, Jie Chen, Ronghua Tang, You Shi, Shuai Zhou, Haifeng Yang
Publikováno v:
Frontiers in Pharmacology, Vol 14 (2023)
Acquired brain injury (ABI) is the most common disease of the nervous system, involving complex pathological processes, which often leads to a series of nervous system disorders. The structural destruction and dysfunction of the Neurovascular Unit (N
Externí odkaz:
https://doaj.org/article/d0a9ee3997c14b42b3bcf7a51cb76907
Publikováno v:
Frontiers in Molecular Neuroscience, Vol 15 (2022)
Externí odkaz:
https://doaj.org/article/1d66afef98e74d66810ecad6a97e5fdf
Akademický článek
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Autor:
Napatsorn Saiyasit, Evan-Angelo R. Butlig, Samantha D. Chaney, Miranda K. Traylor, Nanako A. Hawley, Ryleigh B. Randall, Hanna V. Bobinger, Carl A. Frizell, Franklin Trimm, Errol D. Crook, Mike Lin, Benjamin D. Hill, Joshua L. Keller, Amy R. Nelson
Publikováno v:
Frontiers in Neuroscience, Vol 16 (2022)
Alzheimer’s disease and related dementias (ADRD) are an expanding worldwide crisis. In the absence of scientific breakthroughs, the global prevalence of ADRD will continue to increase as more people are living longer. Racial or ethnic minority grou
Externí odkaz:
https://doaj.org/article/cb9fe15b670346d8b518eaee24f239b2
Peripheral Pathways to Neurovascular Unit Dysfunction, Cognitive Impairment, and Alzheimer’s Disease
Autor:
Amy R. Nelson
Publikováno v:
Frontiers in Aging Neuroscience, Vol 14 (2022)
Alzheimer’s disease (AD) is the most common form of dementia. It was first described more than a century ago, and scientists are acquiring new data and learning novel information about the disease every day. Although there are nuances and details c
Externí odkaz:
https://doaj.org/article/fe0a3712ce1346c0a9b4531f08446a59
Autor:
Xiumiao Li, Junya Zhu, Yuling Zhong, Chang Liu, Mudi Yao, Yanan Sun, Wen Yao, Xisen Ni, Fen Zhou, Jin Yao, Qin Jiang
Publikováno v:
EBioMedicine, Vol 77, Iss , Pp 103857- (2022)
Summary: Background: Diabetic retinopathy (DR) is a leading cause of blindness in the working-age population, which is characterized by retinal neurodegeneration and vascular dysfunction. Long non-coding RNAs (LncRNAs) have emerged as critical regula
Externí odkaz:
https://doaj.org/article/ef959312013d48ac951e4d7aa75bcdde