Zobrazeno 1 - 10
of 2 919
pro vyhledávání: '"neurosteroid"'
Autor:
Maria Katharina Grötsch, Ulrike Ehlert
Publikováno v:
Frontiers in Behavioral Neuroscience, Vol 18 (2024)
BackgroundAllopregnanolone (ALLO), a neuroactive steroid hormone derived from progesterone, can modulate mood via the GABA-A receptor. Peripartum mood can be influenced by psychosocial factors, previous mental illness, and hormonal changes. Studies s
Externí odkaz:
https://doaj.org/article/b4cf58904f334a9eb066eeb7ac0f4f42
Publikováno v:
Brain and Behavior, Vol 14, Iss 9, Pp n/a-n/a (2024)
Abstract Background Preterm birth is associated with brain injury and long‐term behavioral abnormalities, for which there are limited prevention options. When born preterm, infants prematurely lose placental neurosteroid (allopregnanolone) support.
Externí odkaz:
https://doaj.org/article/eb59e0232e1c4d4a81285f01def0385f
Publikováno v:
Brain Circulation, Vol 10, Iss 1, Pp 5-10 (2024)
Ischemic stroke is a major global health crisis, characterized by high morbidity and mortality rates. Although there have been significant advancements in treating the acute phase of this condition, there remains a pressing need for effective treatme
Externí odkaz:
https://doaj.org/article/bdd210cec44f4cd8a7f803d9c0451a43
Autor:
Fu-Rong Xu, Zhen-Hong Wei, Xiao-Xia Xu, Xiao-Gang Zhang, Chao-Jun Wei, Xiao-Ming Qi, Yong-Hong Li, Xiao-Ling Gao, Yu Wu
Publikováno v:
Journal of Neuroinflammation, Vol 20, Iss 1, Pp 1-22 (2023)
Abstract Background Depression is two-to-three times more frequent among women. The hypothalamus, a sexually dimorphic area, has been implicated in the pathophysiology of depression. Neuroinflammation-induced hypothalamic dysfunction underlies behavi
Externí odkaz:
https://doaj.org/article/bf3bd44b943e4fd18fd71de53930137f
Publikováno v:
Armaghane Danesh Bimonthly Journal, Vol 28, Iss 5, Pp 621-637 (2023)
Background & aim: Pregnenolone acts as a precursor to other steroid hormones and exerts its effect as an anti-inflammatory molecule to maintain immune homeostasis in various inflammatory conditions. In these diseases, a decrease in the level ofP has
Externí odkaz:
https://doaj.org/article/98e60b1a22b94be78c6b76de38536e57
Publikováno v:
Frontiers in Psychiatry, Vol 14 (2023)
With each passing year, the number of people suffering from mental disorders grows at a disturbing speed. Neuroactive steroids are a new promising group of drugs with the potential for use in many diseases like postpartum depression, postnatal psycho
Externí odkaz:
https://doaj.org/article/028367436b8549ba88b68a21e172f1aa
Publikováno v:
مجله علمی دانشگاه علوم پزشکی کردستان, Vol 28, Iss 1, Pp 30-39 (2023)
Background and Aim: Anticonvulsive effects of neurosteroids were shown in animal models. Endocannabinoids modulate neuronal excitability. In this study, we investigated the synergism of the simultaneous application of Palmitoylethanolamide (PEA) as a
Externí odkaz:
https://doaj.org/article/e085ded649e343a2b7aee02cd525b131
Autor:
Irina Balan, Giorgia Boero, Samantha Lucenell Chéry, Minna H. McFarland, Alejandro G. Lopez, A. Leslie Morrow
Publikováno v:
Life, Vol 14, Iss 5, p 582 (2024)
Pregnane neuroactive steroids, notably allopregnanolone and pregnenolone, exhibit efficacy in mitigating inflammatory signals triggered by toll-like receptor (TLR) activation, thus attenuating the production of inflammatory factors. Clinical studies
Externí odkaz:
https://doaj.org/article/fca29f2a91c74860ad3a637d1bf388ce
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