Zobrazeno 1 - 10
of 203
pro vyhledávání: '"neuroprotectants"'
Publikováno v:
Exploration of Neuroprotective Therapy, Vol 3, Iss 5, Pp 398-408 (2023)
Aim: Stroke is the second most common cause of mortality and disability worldwide with ischemic strokes being the predominant type. The advent of neuroprotectants brought hope of improved outcomes and quality of life, but current guidelines, despite
Externí odkaz:
https://doaj.org/article/380b3f7493644bbfaa88c8d37339fd55
Publikováno v:
Antioxidants, Vol 12, Iss 9, p 1694 (2023)
Choroideremia (CHM) is a rare X-linked chorioretinal dystrophy, affecting the photoreceptors, retinal pigment epithelium (RPE) and choroid, with no approved therapy. CHM is caused by mutations in the CHM gene, which encodes the ubiquitously expressed
Externí odkaz:
https://doaj.org/article/48d6860dcce8428aba06ebf7f4c07a3a
Autor:
Mária Lalkovicova
Publikováno v:
Neural Regeneration Research, Vol 17, Iss 9, Pp 1885-1892 (2022)
Ionizing radiation caused by medical treatments, nuclear events or even space flights can irreversibly damage structure and function of brain cells. That can result in serious brain damage, with memory and behavior disorders, or even fatal oncologic
Externí odkaz:
https://doaj.org/article/4ac27f08dda94e7f8f2c433fcece918f
Autor:
Hui Zhang, Laifa Wang, Yongping Yang, Chuanhai Cai, Xueqin Wang, Ling Deng, Binsheng He, Wenhu Zhou, Yanhui Cui
Publikováno v:
Frontiers in Pharmacology, Vol 13 (2023)
Currently, the recovery of cognitive function has become an essential part of stroke rehabilitation. DL-3-n-butylphthalide (NBP) is a neuroprotective reagent and has been used in stroke treatment. Clinical studies have confirmed that NBP can achieve
Externí odkaz:
https://doaj.org/article/57888a33873649c9823d7030c7d91b59
Autor:
Hui Zhang, Chuan-Ling Li, Feng Wan, Su-Juan Wang, Xiu-E Wei, Yan-Lei Hao, Hui-Lin Leng, Jia-Min Li, Zhong-Rui Yan, Bao-Jun Wang, Ren-Shi Xu, Ting-Min Yu, Li-Chun Zhou, Dong-Sheng Fan
Publikováno v:
Neural Regeneration Research, Vol 15, Iss 7, Pp 1266-1273 (2020)
Cattle encephalon glycoside and ignotin (CEGI) injection is a compound preparation formed by a combination of muscle extract from healthy rabbits and brain gangliosides from cattle, and it is generally used as a neuroprotectant in the treatment of ce
Externí odkaz:
https://doaj.org/article/d75863127527444ab7ad95bdf0a2cfbe
Autor:
Liyun Zhang, Conan Chen, Jie Fu, Brendan Lilley, Cynthia Berlinicke, Baranda Hansen, Ding Ding, Guohua Wang, Tao Wang, Daniel Shou, Ying Ye, Timothy Mulligan, Kevin Emmerich, Meera T Saxena, Kelsi R Hall, Abigail V Sharrock, Carlene Brandon, Hyejin Park, Tae-In Kam, Valina L Dawson, Ted M Dawson, Joong Sup Shim, Justin Hanes, Hongkai Ji, Jun O Liu, Jiang Qian, David F Ackerley, Baerbel Rohrer, Donald J Zack, Jeff S Mumm
Publikováno v:
eLife, Vol 10 (2021)
Retinitis pigmentosa (RP) and associated inherited retinal diseases (IRDs) are caused by rod photoreceptor degeneration, necessitating therapeutics promoting rod photoreceptor survival. To address this, we tested compounds for neuroprotective effects
Externí odkaz:
https://doaj.org/article/ae361e62a3fd4acc8161a7ed3eae9011
Publikováno v:
Pharmaceuticals, Vol 15, Iss 7, p 838 (2022)
The present article reviewed the pharmacologic therapies of traumatic brain injury (TBI), including current and potential treatments. Pharmacologic therapies are an essential part of TBI care, and several agents have well-established effects in TBI c
Externí odkaz:
https://doaj.org/article/df38abaa1e0b42b1aac4fd1078fde729
Autor:
Ji Man Hong, Mun Hee Choi, Sung-Il Sohn, Yang-Ha Hwang, Seong Hwan Ahn, Yeong-Bae Lee, Dong-Ick Shin, Ángel Chamorro, Dennis W. Choi, on the behalf of the SONIC investigators
Publikováno v:
Trials, Vol 19, Iss 1, Pp 1-7 (2018)
Abstract Background The potential of neuroprotective agents should be revisited in the era of endovascular thrombectomy (EVT) for acute large-artery occlusion because their preclinical effects have been optimized for ischemia and reperfusion injury.
Externí odkaz:
https://doaj.org/article/c232a69aa06c459581312b7fdf785aab
Publikováno v:
Неотложная медицинская помощь, Vol 7, Iss 1, Pp 44-52 (2018)
The article shows the world experience of metabolic therapy use in the treatment of ischemic stroke. The issue still remains prominent. The reasonability of prescribing metabolic drugs is not completely clear, its effectiveness has not been fully pro
Externí odkaz:
https://doaj.org/article/3f0920bf11bf4876af9467d4bc9b9577
Autor:
Tai, Kwok-Keung, Blondelle, Sylvie E., Ostresh, John M., Houghten, Richard A., Montal, Mauricio
Publikováno v:
Proceedings of the National Academy of Sciences of the United States of America, 2001 Mar . 98(6), 3519-3524.
Externí odkaz:
https://www.jstor.org/stable/3055267