DeepNeuropePred: A robust and universal tool to predict cleavage sites from neuropeptide precursors by protein language model

Autor: Lei Wang, Zilu Zeng, Zhidong Xue, Yan Wang

Publikováno v: Computational and Structural Biotechnology Journal, Vol 23, Iss , Pp 309-315 (2024)

Neuropeptides play critical roles in many biological processes such as growth, learning, memory, metabolism, and neuronal differentiation. A few approaches have been reported for predicting neuropeptides that are cleaved from precursor protein sequen

Externí odkaz: https://doaj.org/article/b59414622b324e2e81b6a1e9d80437c5

DeepNeuropePred: A robust and universal tool to predict cleavage sites from neuropeptide precursors by protein language model.

Autor: Wang L; Institute of Medical Artificial Intelligence, Binzhou Medical University, Yantai, Shandong 264003, China.; School of Life Science and Technology, Huazhong University of Science and Technology, Wuhan, Hubei 430074, China., Zeng Z; Wuhan Children's Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan, Hubei 430010, China., Xue Z; Institute of Medical Artificial Intelligence, Binzhou Medical University, Yantai, Shandong 264003, China.; School of Software Engineering, Huazhong University of Science and Technology, Wuhan, Hubei 430074, China., Wang Y; Institute of Medical Artificial Intelligence, Binzhou Medical University, Yantai, Shandong 264003, China.; School of Life Science and Technology, Huazhong University of Science and Technology, Wuhan, Hubei 430074, China.

Publikováno v: Computational and structural biotechnology journal [Comput Struct Biotechnol J] 2023 Dec 05; Vol. 23, pp. 309-315. Date of Electronic Publication: 2023 Dec 05 (Print Publication: 2024).

Evolution of Neuropeptide Precursors in Polyneoptera (Insecta)

Autor: Marcel Bläser, Reinhard Predel

Publikováno v: Frontiers in Endocrinology, Vol 11 (2020)

Neuropeptides are among the structurally most diverse signaling molecules and participate in intercellular information transfer from neurotransmission to intrinsic or extrinsic neuromodulation. Many of the peptidergic systems have a very ancient orig

Externí odkaz: https://doaj.org/article/bf183a46212045659095c2832a5d3162

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