Multiscale Cloud-Based Pipeline for Neuronal Electrophysiology Analysis and Visualization.

Autor: Geng J; Department of Electrical and Computer Engineering, University of California Santa Cruz, Santa Cruz, CA 95064, USA.; Genomics Institute, University of California Santa Cruz, Santa Cruz, CA 95064, USA., Voitiuk K; Department of Electrical and Computer Engineering, University of California Santa Cruz, Santa Cruz, CA 95064, USA.; Department of Biomolecular Engineering, University of California Santa Cruz, Santa Cruz, CA 95064, USA.; Genomics Institute, University of California Santa Cruz, Santa Cruz, CA 95064, USA., Parks DF; Department of Biomolecular Engineering, University of California Santa Cruz, Santa Cruz, CA 95064, USA.; Genomics Institute, University of California Santa Cruz, Santa Cruz, CA 95064, USA., Robbins A; Department of Electrical and Computer Engineering, University of California Santa Cruz, Santa Cruz, CA 95064, USA.; Genomics Institute, University of California Santa Cruz, Santa Cruz, CA 95064, USA., Spaeth A; Department of Electrical and Computer Engineering, University of California Santa Cruz, Santa Cruz, CA 95064, USA.; Genomics Institute, University of California Santa Cruz, Santa Cruz, CA 95064, USA., Sevetson JL; Department of Molecular, Cell, and Developmental Biology, University of California Santa Cruz, Santa Cruz, CA 95064, USA.; Genomics Institute, University of California Santa Cruz, Santa Cruz, CA 95064, USA., Hernandez S; Department of Electrical and Computer Engineering, University of California Santa Cruz, Santa Cruz, CA 95064, USA.; Genomics Institute, University of California Santa Cruz, Santa Cruz, CA 95064, USA., Schweiger HE; Department of Molecular, Cell, and Developmental Biology, University of California Santa Cruz, Santa Cruz, CA 95064, USA.; Genomics Institute, University of California Santa Cruz, Santa Cruz, CA 95064, USA., Andrews JP; Department of Neurological Surgery, University of California San Francisco, San Francisco, CA 94143, USA., Seiler ST; Department of Electrical and Computer Engineering, University of California Santa Cruz, Santa Cruz, CA 95064, USA.; Department of Biomolecular Engineering, University of California Santa Cruz, Santa Cruz, CA 95064, USA.; Genomics Institute, University of California Santa Cruz, Santa Cruz, CA 95064, USA., Elliott MAT; Department of Biomolecular Engineering, University of California Santa Cruz, Santa Cruz, CA 95064, USA.; Genomics Institute, University of California Santa Cruz, Santa Cruz, CA 95064, USA., Chang EF; Department of Neurological Surgery, University of California San Francisco, San Francisco, CA 94143, USA.; Weill Institute for Neurosciences, University of California San Francisco, San Francisco, CA 94143, USA., Nowakowski TJ; Department of Neurological Surgery, University of California San Francisco, San Francisco, CA 94143, USA.; Weill Institute for Neurosciences, University of California San Francisco, San Francisco, CA 94143, USA.; The Eli and Edythe Broad Center of Regeneration Medicine and Stem Cell Research, University of California San Francisco, San Francisco, CA 94143, USA.; Department of Psychiatry and Behavioral Sciences, University of California San Francisco, San Francisco, CA 94143, USA.; Department of Anatomy, University of California San Francisco, San Francisco, CA 94143, USA., Currie R; Genomics Institute, University of California Santa Cruz, Santa Cruz, CA 95064, USA., Mostajo-Radji MA; Genomics Institute, University of California Santa Cruz, Santa Cruz, CA 95064, USA., Haussler D; Department of Biomolecular Engineering, University of California Santa Cruz, Santa Cruz, CA 95064, USA.; Genomics Institute, University of California Santa Cruz, Santa Cruz, CA 95064, USA., Sharf T; Department of Biomolecular Engineering, University of California Santa Cruz, Santa Cruz, CA 95064, USA.; Genomics Institute, University of California Santa Cruz, Santa Cruz, CA 95064, USA., Salama SR; Department of Molecular, Cell, and Developmental Biology, University of California Santa Cruz, Santa Cruz, CA 95064, USA.; Genomics Institute, University of California Santa Cruz, Santa Cruz, CA 95064, USA., Teodorescu M; Department of Electrical and Computer Engineering, University of California Santa Cruz, Santa Cruz, CA 95064, USA.; Department of Biomolecular Engineering, University of California Santa Cruz, Santa Cruz, CA 95064, USA.; Genomics Institute, University of California Santa Cruz, Santa Cruz, CA 95064, USA.; Lead Contact.

Publikováno v: BioRxiv : the preprint server for biology [bioRxiv] 2024 Dec 14. Date of Electronic Publication: 2024 Dec 14.

Manifold learning analysis suggests strategies to align single-cell multimodal data of neuronal electrophysiology and transcriptomics.

Autor: Huang, Jiawei^1,2 (AUTHOR), Sheng, Jie³ (AUTHOR), Wang, Daifeng^3,4,5 (AUTHOR) daifeng.wang@wisc.edu

Publikováno v: Communications Biology. 11/19/2021, Vol. 4 Issue 1, p1-10. 10p.

Role of Akt-independent mTORC1 and GSK3β signaling in sublethal NMDA-induced injury and the recovery of neuronal electrophysiology and survival

Autor: Przemyslaw Swiatkowski, Ina Nikolaeva, Gaurav Kumar, Avery Zucco, Barbara F. Akum, Mihir V. Patel, Gabriella D’Arcangelo, Bonnie L. Firestein

Publikováno v: Scientific Reports, Vol 7, Iss 1, Pp 1-16 (2017)

Abstract Glutamate-induced excitotoxicity, mediated by overstimulation of N-methyl-D-aspartate (NMDA) receptors, is a mechanism that causes secondary damage to neurons. The early phase of injury causes loss of dendritic spines and changes to synaptic

Externí odkaz: https://doaj.org/article/187734828ebb47e29e21b6060cf27c55

Tento výsledek nelze pro nepřihlášené uživatele zobrazit.
K zobrazení výsledku je třeba se přihlásit.

Quantum dot-based multiphoton fluorescent pipettes for targeted neuronal electrophysiology.

Autor: Andrásfalvy, Bertalan K¹, Galiñanes, Gregorio L², Huber, Daniel², Barbic, Mladen³, Macklin, John J³, Susumu, Kimihiro⁴, Delehanty, James B⁵, Huston, Alan L⁶, Makara, Judit K¹, Medintz, Igor L⁵

Publikováno v: Nature Methods. Dec2014, Vol. 11 Issue 12, p1237-1241. 5p. 3 Graphs.