Zobrazeno 1 - 10
of 18 305
pro vyhledávání: '"neurodegenerative disease"'
Autor:
Ting Zhang, Wenjing Rui, Yue Sun, Yunyun Tian, Qiaoyan Li, Qian Zhang, Yanchun Zhao, Zongzhi Liu, Tiepeng Wang
Publikováno v:
Molecular Biomedicine, Vol 5, Iss 1, Pp 1-18 (2024)
Abstract Parkinson's disease (PD) involves multiple forms of neuronal cell death, but the dominant pathway involved in disease progression remains unclear. This study employed RNA sequencing (RNA-seq) of brain tissue to explore gene expression patter
Externí odkaz:
https://doaj.org/article/f64e84197b6c44c5b9ffbdba9e4200a0
Autor:
Sydney E. Prange, Isha N. Bhakta, Daria Sysoeva, Grace E. Jean, Anjali Madisetti, Hieu H. N. Le, Ly U. Duong, Patrick T. Hwu, Jaela G. Melton, Katherine L. Thompson-Peer
Publikováno v:
Scientific Reports, Vol 14, Iss 1, Pp 1-18 (2024)
Abstract Dendrite defects and loss are early cellular alterations observed across neurodegenerative diseases that play a role in early disease pathogenesis. Dendrite degeneration can be modeled by expressing pathogenic polyglutamine disease transgene
Externí odkaz:
https://doaj.org/article/99f3e971b3d24e67ab0d10d21c753884
Autor:
Emilio A. Cafferata, Ausra Ramanauskaite, Astrid Cuypers, Karina Obreja, Eva Dohle, Shahram Ghanaati, Frank Schwarz
Publikováno v:
BMC Oral Health, Vol 24, Iss 1, Pp 1-15 (2024)
Abstract Purpose Cumulating evidence supports the close association between periodontal diseases, neuroinflammation and neurodegenerative pathologies, except for peri-implantitis (PI). Thus, this study explored the association between experimental PI
Externí odkaz:
https://doaj.org/article/1a12b2a0055d4a5d8de4275c4e3898f1
Autor:
Xiaoxi Du, Jongchan Park, Ruixuan Zhao, R. Theodore Smith, Yosef Koronyo, Maya Koronyo-Hamaoui, Liang Gao
Publikováno v:
Acta Neuropathologica Communications, Vol 12, Iss 1, Pp 1-16 (2024)
Abstract While Alzheimer’s disease and other neurodegenerative diseases have traditionally been viewed as brain disorders, there is growing evidence indicating their manifestation in the eyes as well. The retina, being a developmental extension of
Externí odkaz:
https://doaj.org/article/3632fd0cea324da0976e2cb381bcf9dd
Publikováno v:
Discover Nano, Vol 19, Iss 1, Pp 1-21 (2024)
Abstract With the size of the aging population increasing worldwide, the effective diagnosis and treatment of neurodegenerative diseases (NDDs) has become more important. Two-dimensional (2D) materials offer specific advantages for the diagnosis and
Externí odkaz:
https://doaj.org/article/f39b62fc36ef4a09ae7a381b34774380
Publikováno v:
Jichu yixue yu linchuang, Vol 44, Iss 9, Pp 1298-1302 (2024)
Parkinson′s disease (PD) is the second most common neurodegenerative disease, mainly due to the loss of dopaminergic neurons in the substantia nigra (SN) of the midbrain, resulting in motor dysfunction. Dental stem cells (DSCs) are derived from the
Externí odkaz:
https://doaj.org/article/0b5dfc845dd14ddc990283cf56ff8ed9
Publikováno v:
Scientific Reports, Vol 14, Iss 1, Pp 1-18 (2024)
Abstract Huntington’s disease (HD) is a rare neurodegenerative disease caused due to aggregation of Huntingtin (HTT) protein. This study involves the cloning of 40 DnaJ chaperones from Drosophila, and overexpressing them in yeasts and fly models of
Externí odkaz:
https://doaj.org/article/f23e0c0101c14016a2d49203166a839b
Publikováno v:
Guoji Yanke Zazhi, Vol 24, Iss 9, Pp 1426-1431 (2024)
Diabetic retinopathy(DR)is one of the major complications of diabetes mellitus, characterized by neurodegeneration and microangiopathy. Currently, the treatment of DR is mainly focused on the management of late complications and has not achieved the
Externí odkaz:
https://doaj.org/article/3ed328bf99da4711a0b3994dda84882b
Publikováno v:
Neural Regeneration Research, Vol 20, Iss 2, Pp 598-608 (2025)
Photobiomodulation, originally used red and near-infrared lasers, can alter cellular metabolism. It has been demonstrated that the visible spectrum at 451–540 nm does not necessarily increase cell proliferation, near-infrared light promotes adipose
Externí odkaz:
https://doaj.org/article/801af05dd25c44afaa633349e7e32793
Autor:
Alessio Canovai, Pete A. Williams
Publikováno v:
Neural Regeneration Research, Vol 20, Iss 1, Pp 41-53 (2025)
Pyrroloquinoline quinone is a quinone described as a cofactor for many bacterial dehydrogenases and is reported to exert an effect on metabolism in mammalian cells/tissues. Pyrroloquinoline quinone is present in the diet being available in foodstuffs
Externí odkaz:
https://doaj.org/article/8d3f6a9b19014f6da82ca259e018a949