Zobrazeno 1 - 10
of 178
pro vyhledávání: '"neuraminidase (NA)"'
Publikováno v:
Human Vaccines & Immunotherapeutics, Vol 20, Iss 1 (2024)
Influenza neuraminidase (NA) is a promising target for a broadly protective vaccine. In this study, the Computationally Optimized Broadly Reactive Antigen (COBRA) methodology was used to develop N2 NA vaccine candidates. The unique wild type (WT) N2
Externí odkaz:
https://doaj.org/article/808c884f5b284367ac1cab0aeff99f14
Publikováno v:
Journal of Functional Foods, Vol 112, Iss , Pp 105940- (2024)
Hoveniae Semen Seu Fructus (HSF) is a fruit and seed of Hovenia dulcis Thunb. Here, we first report HSF water extract contains a potent anti-influenza A virus (IAV) effect via inhibition of neuraminidase and hemagglutinin and a direct virus-killing e
Externí odkaz:
https://doaj.org/article/388e4824dbad4c879740a66c97c4c66a
Publikováno v:
Virus Research, Vol 335, Iss , Pp 199199- (2023)
Thuja orientalis Folium (TOF) has been prescribed traditionally as an expectorant for inflammatory airway disease. In this study, we evaluated the anti-influenza A virus (IAV) activity of TOF by detecting GFP expressed by influenza A virus (A/PR/8/34
Externí odkaz:
https://doaj.org/article/320b19332afe452fa9c40a0cf5595a97
Autor:
Vanessa Escuret, Olivier Terrier
Publikováno v:
Frontiers in Microbiology, Vol 14 (2023)
The activity of sialic acids, known to play critical roles in biology and many pathological processes, is finely regulated by a class of enzymes called sialidases, also known as neuraminidases. These are present in mammals and many other biological s
Externí odkaz:
https://doaj.org/article/ce46695a92e243c4a9d812a9a4fe1334
Autor:
Thiago das Chagas Sousa, Jessica Santa Cruz Carvalho Martins, Milene Dias Miranda, Cristiana Couto Garcia, Paola Cristina Resende, Cliomar A. Santos, Maria do Carmo Debur, Rodrigo Ribeiro Rodrigues, Andrea Cony Cavalcanti, Tatiana Schäffer Gregianini, Felipe Campos de Melo Iani, Felicidade Mota Pereira, Sandra Bianchini Fernandes, Jessylene de Almeida Ferreira, Katia Correa de Oliveira Santos, Fernando Motta, David Brown, Walquiria Aparecida Ferreira de Almeida, Marilda Mendonça Siqueira, Aline da Rocha Matos
Publikováno v:
Frontiers in Public Health, Vol 10 (2022)
The influenza A virus (IAV) is of a major public health concern as it causes annual epidemics and has the potential to cause pandemics. At present, the neuraminidase inhibitors (NAIs) are the most widely used anti-influenza drugs, but, more recently,
Externí odkaz:
https://doaj.org/article/c5d7be96979748cb906cc0e43c3f17c4
Akademický článek
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Akademický článek
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Autor:
Natalia A. Ilyushina, Takashi E. Komatsu, William L. Ince, Eric F. Donaldson, Nicolette Lee, Julian J. O’Rear, Raymond P. Donnelly
Publikováno v:
Virology Journal, Vol 16, Iss 1, Pp 1-9 (2019)
Abstract Background Vaccination and the use of neuraminidase inhibitors (NAIs) are currently the front lines of defense against seasonal influenza. The activity of influenza vaccines and antivirals drugs such as the NAIs can be affected by mutations
Externí odkaz:
https://doaj.org/article/d26eb6e3cedd43168e4d091b4fc2e0b7
Autor:
Álvaro López-Valiñas, Laura Baioni, Lorena Córdoba, Ayub Darji, Chiara Chiapponi, Joaquim Segalés, Llilianne Ganges, José I. Núñez
Publikováno v:
Viruses, Vol 14, Iss 9, p 2008 (2022)
Swine influenza viruses (SIV) produce a highly contagious and worldwide distributed disease that can cause important economic losses to the pig industry. Currently, this virus is endemic in farms and, although used limitedly, trivalent vaccine applic
Externí odkaz:
https://doaj.org/article/4b4908e86921455db96911333683777a
Autor:
Irisa Trianti, Saengchai Akeprathumchai, Phenjun Mekvichitsaeng, Sansanalak Rachdawong, Kanokwan Poomputsa
Publikováno v:
AMB Express, Vol 8, Iss 1, Pp 1-9 (2018)
Abstract Baculovirus is a promising vaccine deliver vector due to its biosafety profiles, gene transfer efficiency, ability to display small foreign antigens on its surface, strong adjuvant activities, etc. A dual vector for peptide antigens and a DN
Externí odkaz:
https://doaj.org/article/107a15ff5abd42b3b31a5bb560025da1