Zobrazeno 1 - 10
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pro vyhledávání: '"neural tube closure"'
Akademický článek
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Autor:
Zihao Deng, Marina R. Carpinelli, Tariq Butt, Graham W. Magor, Peinan Zhao, Kevin R. Gillinder, Andrew C. Perkins, Stephen M. Jane
Publikováno v:
Heliyon, Vol 10, Iss 17, Pp e37259- (2024)
Neural tube closure in vertebrates is achieved through a highly dynamic and coordinated series of morphogenic events involving neuroepithelium, surface ectoderm, and neural plate border. Failure of this process in the caudal region causes spina bifid
Externí odkaz:
https://doaj.org/article/631a6d4ff0564bf78c5f7172dabd262e
Autor:
Deng, Zihao a, ⁎, Carpinelli, Marina R. a, Butt, Tariq a, Magor, Graham W. b, c, Zhao, Peinan a, Gillinder, Kevin R. b, d, Perkins, Andrew C. b, Jane, Stephen M. a, ⁎⁎
Publikováno v:
In Heliyon 15 September 2024 10(17)
Publikováno v:
Frontiers in Cell and Developmental Biology, Vol 11 (2023)
Introduction: Neural tube defects (NTDs) are among the most debilitating and common developmental defects in humans. The induction of NTDs has been attributed to abnormal folic acid (vitamin B9) metabolism, Wnt and BMP signaling, excess retinoic acid
Externí odkaz:
https://doaj.org/article/78671b6d61364fc29563005f04121777
Akademický článek
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Autor:
Daisuke Sakai, Yuki Murakami, Daichi Shigeta, Mitsuhiro Tomosugi, Hiromi Sakata-Haga, Toshihisa Hatta, Hiroki Shoji
Publikováno v:
Frontiers in Cell and Developmental Biology, Vol 11 (2023)
Physiological hypoxia is critical for placental mammalian development. However, the underlying mechanisms by which hypoxia regulates embryonic development remain unclear. We discovered that the expression of glycolytic genes partially depends on hypo
Externí odkaz:
https://doaj.org/article/c695255b4047453a85f7cba2e7c2ed3c
Publikováno v:
Frontiers in Cell and Developmental Biology, Vol 10 (2023)
Neural tube closure is a fundamental process during vertebrate embryogenesis, which leads to the formation of the central nervous system. Defective neural tube closure leads to neural tube defects which are some of the most common human birth defects
Externí odkaz:
https://doaj.org/article/ab963088b1b44c339dd7ff6aac79f2f0
Publikováno v:
Frontiers in Cell and Developmental Biology, Vol 10 (2022)
Pax3/7 factors play numerous roles in the development of the dorsal nervous system of vertebrates. From specifying neural crest at the neural plate borders, to regulating neural tube closure and patterning of the resulting neural tube. However, it is
Externí odkaz:
https://doaj.org/article/5a97dab661474ff0a911803c5f45dccf
Publikováno v:
Neural Development, Vol 15, Iss 1, Pp 1-15 (2020)
Abstract Background Neural tube defects (NTDs) are failure of neural tube closure, which includes multiple central nervous system phenotypes. More than 300 mouse mutant strains exhibits NTDs phenotypes and give us some clues to establish association
Externí odkaz:
https://doaj.org/article/039d9dda8d584a1683fce24beb3db1b4
Publikováno v:
eLife, Vol 11 (2022)
Failures of neural tube closure are common and serious birth defects, yet we have a poor understanding of the interaction of genetics and cell biology during neural tube closure. Additionally, mutations that cause neural tube defects (NTDs) tend to a
Externí odkaz:
https://doaj.org/article/dc4f4081279b4799bbaa641b494f58cb