Zobrazeno 1 - 10
of 1 083
pro vyhledávání: '"neural progenitor cell"'
Multi-target regulatory mechanism of Yang Xin Tang − a traditional Chinese medicine against dementia
Autor:
Tung Yan Lo, Anthony Siu Lung Chan, Suet Ting Cheung, Lisa Ying Yung, Manton Man Hon Leung, Yung Hou Wong
Publikováno v:
Chinese Medicine, Vol 18, Iss 1, Pp 1-19 (2023)
Abstract Background Yang Xin Tang (YXT) is a traditional Chinese herbal preparation which has been reported to improve cognitive function and memory in patients with dementia. As the underlying mechanism of action of YXT has not been elucidated, we e
Externí odkaz:
https://doaj.org/article/b31ead40671b42468a6dd508092d63dd
Autor:
Hang Ji, Fang Wang, Zhihui Liu, Yue Li, Haogeng Sun, Anqi Xiao, Huanxin Zhang, Chao You, Shaoshan Hu, Yi Liu
Publikováno v:
Journal of Translational Medicine, Vol 21, Iss 1, Pp 1-15 (2023)
Abstract Background Accurately predicting the outcome of isocitrate dehydrogenase (IDH) wild-type glioblastoma (GBM) remains hitherto challenging. This study aims to Construct and Validate a Robust Prognostic Model for IDH wild-type GBM (COVPRIG) for
Externí odkaz:
https://doaj.org/article/793b064f4a1641aba29b164143b7d557
Publikováno v:
Neurobiology of Disease, Vol 192, Iss , Pp 106431- (2024)
Mutations of the human TRAFFICKING PROTEIN PARTICLE COMPLEX SUBUNIT 9 (TRAPPC9) cause a neurodevelopmental disorder characterised by microcephaly and intellectual disability. Trappc9 constitutes a subunit specific to the intracellular membrane-associ
Externí odkaz:
https://doaj.org/article/7ab356e7d80e460b8473088d9e38bb04
Publikováno v:
Frontiers in Cell and Developmental Biology, Vol 12 (2024)
Microglia are immune cells in the brain that originate from the yolk sac and enter the developing brain before birth. They play critical roles in brain development by supporting neural precursor proliferation, synaptic pruning, and circuit formation.
Externí odkaz:
https://doaj.org/article/05a6b0be2ade4fee8f15eec9eb7c305c
Autor:
Wan-Kyu Ko, Haram Nah, Seong Jun Kim, Gong Ho Han, Daye Lee, Jae Seo Lee, Dong Nyoung Heo, Donghyun Lee, Sang Jin Lee, Min Heo, Seung Hun Sheen, Il Keun Kwon, Seil Sohn
Publikováno v:
Materials & Design, Vol 232, Iss , Pp 112181- (2023)
Transplanted cells rarely survive because of the inflammatory cytokines after spinal cord injury. To increase the survival, we synthesized a hydrophilic and aligned nanofibrous mat. We electrospun thiolate (SH)/aligned (A) poly(lactic-co-glycolic aci
Externí odkaz:
https://doaj.org/article/7d6198d2b7d842089bda68e5a31c0aa7
Akademický článek
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Akademický článek
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Autor:
Kazuyuki Togo, Hayato Fukusumi, Tomoko Shofuda, Hiroshi Ohnishi, Hiroyuki Yamazaki, Mariko Kato Hayashi, Nana Kawasaki, Nobuyuki Takei, Takanobu Nakazawa, Yumiko Saito, Kousuke Baba, Hitoshi Hashimoto, Yuko Sekino, Tomoaki Shirao, Hideki Mochizuki, Yonehiro Kanemura
Publikováno v:
Molecular Brain, Vol 14, Iss 1, Pp 1-17 (2021)
Abstract The generation of mature synaptic structures using neurons differentiated from human-induced pluripotent stem cells (hiPSC-neurons) is expected to be applied to physiological studies of synapses in human cells and to pathological studies of
Externí odkaz:
https://doaj.org/article/b05368a3e53c47ce9dff358d956e3092
Publikováno v:
Frontiers in Cell and Developmental Biology, Vol 10 (2022)
Microglia, the primary immune cells of the brain, significantly influence the fate of neurons after neural damage. Depending on the local environment, they exhibit a wide range of phenotypes, including patrolling (naïve), proinflammatory, and anti-i
Externí odkaz:
https://doaj.org/article/51edf91c7d484bc58a643f06f51bab9f
Akademický článek
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