Zobrazeno 1 - 10
of 36
pro vyhledávání: '"neural progenitor/stem cells"'
Publikováno v:
Protein & Cell, Vol 7, Iss 9, Pp 624-637 (2016)
Abstract Living organisms are exposed to the geomagnetic field (GMF) throughout their lifespan. Elimination of the GMF, resulting in a hypogeomagnetic field (HMF), leads to central nervous system dysfunction and abnormal development in animals. Howev
Externí odkaz:
https://doaj.org/article/12c22ccc9ea74fa380dd0ce4849bf641
Autor:
Angelino Calderone
Publikováno v:
Frontiers in Cell and Developmental Biology, Vol 6 (2018)
The intermediate filament protein nestin was identified in diverse populations of cells implicated in cardiovascular remodeling. Cardiac resident neural progenitor/stem cells constitutively express nestin and following an ischemic insult migrate to t
Externí odkaz:
https://doaj.org/article/c81c1467185c4a9ab949f0cb26c08d23
Publikováno v:
Stem Cells Translational Medicine
Stem Cells Translational Medicine, Vol 10, Iss S2, Pp S31-S40 (2021)
Stem Cells Translational Medicine, Vol 10, Iss S2, Pp S31-S40 (2021)
Brain degeneration and damage is difficult to cure due to the limited endogenous repair capability of the central nervous system. Furthermore, drug development for treatment of diseases of the central nervous system remains a major challenge. However
Autor:
Courtney McDonald, Madison C. B. Paton, Madeleine J. Smith, Suzanne L. Miller, Michael C Fahey, Graham Jenkin, Megan Finch-Edmondson
Publikováno v:
Stem Cells Translational Medicine, Vol 10, Iss 12, Pp 1621-1636 (2021)
Stem Cells Translational Medicine
Stem Cells Translational Medicine
Perinatal brain injury can lead to significant neurological and cognitive deficits and currently no therapies can regenerate the damaged brain. Neural stem cells (NSCs) have the potential to engraft and regenerate damaged brain tissue. The aim of thi
Publikováno v:
Stem Cells Translational Medicine
Stem Cells Translational Medicine, Vol 10, Iss 12, Pp 1581-1587 (2021)
Stem Cells Translational Medicine, Vol 10, Iss 12, Pp 1581-1587 (2021)
Debilitating diseases of the eye represent a large unmet medical need potentially addressable with stem cell‐based approaches. Over the past decade, the California Institute for Regenerative Medicine (CIRM) has funded and supported the translation,
Publikováno v:
Anatomy & Cell Biology
Agmatine, the primary decarboxylation product of L-arginine, generated from arginine decarboxylase. Since the discovery of agmatine in the mammalian brain in the 1990s, an increasing number of agmatine-mediated effects have been discovered, demonstra
Autor:
Jason J. Ivanusic, Wayne Ng, Shiang Y. Lim, Kwaku Dad Abu-Bonsrah, Mirella Dottori, Jeffrey R. McArthur, Stefano Frausin, Rocio K. Finol-Urdaneta, Sara E. Howden, Lachlan H. Thompson, Serena Viventi
Publikováno v:
Stem Cells Translational Medicine
Stem Cells Translational Medicine, Vol 10, Iss 8, Pp 1157-1169 (2021)
Stem Cells Translational Medicine, Vol 10, Iss 8, Pp 1157-1169 (2021)
Friedreich ataxia (FRDA) is an autosomal recessive disease characterized by degeneration of dorsal root ganglia (DRG) sensory neurons, which is due to low levels of the mitochondrial protein Frataxin. To explore cell replacement therapies as a possib
Autor:
Philipp Koch, Christa E. Müller, Julius A. Steinbeck, Ruven Wilkens, Philip D. Gregory, Daniel Poppe, Marion Schneider, Julia Ladewig, Andreas Reik, David Paschon, Allison Tam, Jonas Doerr, Oliver Brüstle
Publikováno v:
Stem Cells Translational Medicine
As a powerful regulator of cellular homeostasis and metabolism, adenosine is involved in diverse neurological processes including pain, cognition, and memory. Altered adenosine homeostasis has also been associated with several diseases such as depres
Publikováno v:
Stem Cells Translational Medicine
Summary The cell surface antigen prominin-1 (alias CD133) has gained enormous interest in the past 2 decades and given rise to debates as to its utility as a biological stem and cancer stem cell marker. Important and yet often overlooked knowledge th
Autor:
Donald J. Zack, Jie Cheng, Xitiz Chamling, Derek S. Welsbie, Katherine L. Mitchell, Melissa M. Liu, Cynthia A. Berlinicke, Valentin M. Sluch
Publikováno v:
Stem Cells Translational Medicine
Human pluripotent stem cells have the potential to promote biological studies and accelerate drug discovery efforts by making possible direct experimentation on a variety of human cell types of interest. However, stem cell cultures are generally hete