Zobrazeno 1 - 10
of 6 865
pro vyhledávání: '"neural progenitor"'
Autor:
Daiyu Hu, Yuanqing Cao, Chenglin Cai, Guangming Wang, Min Zhou, Luying Peng, Yantao Fan, Qiong Lai, Zhengliang Gao
Publikováno v:
Neural Regeneration Research, Vol 20, Iss 1, Pp 242-252 (2025)
Human brain development is a complex process, and animal models often have significant limitations. To address this, researchers have developed pluripotent stem cell-derived three-dimensional structures, known as brain-like organoids, to more accurat
Externí odkaz:
https://doaj.org/article/6aa971cce0d34d7f919713eeec1c2aa7
Autor:
Ole Vidhammer Bjørnstad, Manuel Carrasco, Kenneth Finne, Vandana Ardawatia, Ingeborg Winge, Cecilie Askeland, Jarle B. Arnes, Gøril Knutsvik, Dimitrios Kleftogiannis, Joao A. Paulo, Lars A. Akslen, Heidrun Vethe
Publikováno v:
EBioMedicine, Vol 108, Iss , Pp 105325- (2024)
Summary: Background: Presence of nerves in tumours, by axonogenesis and neurogenesis, is gaining increased attention for its impact on cancer initiation and development, and the new field of cancer neuroscience is emerging. A recent study in prostate
Externí odkaz:
https://doaj.org/article/b4465446dd87464692b1cff514237eab
Publikováno v:
International Journal of Nanomedicine, Vol Volume 19, Pp 4181-4197 (2024)
Yuxin Bai,1,2 Yanjing Zhu,1 Xiaolie He,1 Ruiqi Huang,1,2 Xu Xu,1 Li Yang,1 Zhaojie Wang,1,2 Rongrong Zhu1,2 1Key Laboratory of Spine and Spinal Cord Injury Repair and Regeneration of Ministry of Education, Department of Orthopedics, Tongji Hospital A
Externí odkaz:
https://doaj.org/article/a0838e5f9b874bc98b12f25fd94ac2eb
Autor:
Katie Williams, Simote T. Foliaki, Brent Race, Anna Smith, Tina Thomas, Bradley R. Groveman, Cathryn L. Haigh
Publikováno v:
Stem Cell Research & Therapy, Vol 14, Iss 1, Pp 1-12 (2023)
Abstract Background Sporadic Creutzfeldt-Jakob disease (sCJD), the most common human prion disease, is a fatal neurodegenerative disease with currently no treatment options. Stem cell therapy for neurodegenerative diseases is emerging as a possible t
Externí odkaz:
https://doaj.org/article/76650160d49145ef9e878b0184a93c70
Publikováno v:
Prion, Vol 17, Iss 1, Pp 116-132 (2023)
ABSTRACTPrions are misfolded proteins that accumulate within the brain in association with a rare group of fatal and infectious neurological disorders in humans and animals. A current challenge to research is a lack of in vitro model systems that are
Externí odkaz:
https://doaj.org/article/f463c871e0d94d7480db5231782a1048
Publikováno v:
Neurobiology of Disease, Vol 192, Iss , Pp 106431- (2024)
Mutations of the human TRAFFICKING PROTEIN PARTICLE COMPLEX SUBUNIT 9 (TRAPPC9) cause a neurodevelopmental disorder characterised by microcephaly and intellectual disability. Trappc9 constitutes a subunit specific to the intracellular membrane-associ
Externí odkaz:
https://doaj.org/article/7ab356e7d80e460b8473088d9e38bb04
Autor:
Inci S. Aksoylu, Pauline Martin, Francis Robert, Krzysztof J. Szkop, Nicholas E. Redmond, Srirupa Bhattacharyya, Jennifer Wang, Shan Chen, Roberta L. Beauchamp, Irene Nobeli, Jerry Pelletier, Ola Larsson, Vijaya Ramesh
Publikováno v:
Molecular Autism, Vol 14, Iss 1, Pp 1-20 (2023)
Abstract Background Tuberous sclerosis complex (TSC) is an inherited neurocutaneous disorder caused by mutations in the TSC1 or TSC2 genes, with patients often exhibiting neurodevelopmental (ND) manifestations termed TSC-associated neuropsychiatric d
Externí odkaz:
https://doaj.org/article/057c7629fc914290bfd51a7dc5438070
Publikováno v:
BMC Veterinary Research, Vol 19, Iss 1, Pp 1-11 (2023)
Abstract Background • Neural stem/progenitor cells (NSPCs) are multipotent self-renewing cells that can be isolated from the brain or spinal cord. As they need to be isolated from neural tissues, it is difficult to study human NSPCs. To facilitate
Externí odkaz:
https://doaj.org/article/954c64eb2a1e4aa5b04fd5ce6c4049cc
Autor:
Bin Lu, Pablo Avalos, Soshana Svendsen, Changqing Zhang, Laura Nocito, Melissa K. Jones, Cosmo Pieplow, Joshua Saylor, Sean Ghiam, Amanda Block, Michael Fernandez, Alexander V. Ljubimov, Kent Small, David Liao, Clive N. Svendsen, Shaomei Wang
Publikováno v:
Journal of Translational Medicine, Vol 21, Iss 1, Pp 1-17 (2023)
Abstract Background Stem cell products are increasingly entering early stage clinical trials for treating retinal degeneration. The field is learning from experience about comparability of cells proposed for preclinical and clinical use. Without this
Externí odkaz:
https://doaj.org/article/fb13a9918ae340d48cb64d12f07d9c03