Zobrazeno 1 - 10
of 48 003
pro vyhledávání: '"nephrotoxicity"'
Publikováno v:
Journal of Medical Case Reports, Vol 18, Iss 1, Pp 1-5 (2024)
Abstract Background Platinum-based antineoplastic drugs are widely used in the treatment of solid tumors. Carboplatin is a safe and efficacious adjuvant treatment for stage I seminoma following a risk-adapted treatment strategy. It consists in the ad
Externí odkaz:
https://doaj.org/article/e6e83a69bf184d73810d4e0e5e47f526
Autor:
Domenico Gadaleta, Marina Garcia de Lomana, Eva Serrano-Candelas, Rita Ortega-Vallbona, Rafael Gozalbes, Alessandra Roncaglioni, Emilio Benfenati
Publikováno v:
Journal of Cheminformatics, Vol 16, Iss 1, Pp 1-17 (2024)
Abstract The adverse outcome pathway (AOP) concept has gained attention as a way to explore the mechanism of chemical toxicity. In this study, quantitative structure–activity relationship (QSAR) models were developed to predict compound activity to
Externí odkaz:
https://doaj.org/article/f64a73920b77456f89cbc33ac1b0126b
Publikováno v:
Research in Pharmaceutical Sciences, Vol 19, Iss 5, Pp 591-605 (2024)
Background and purpose: Doxorubicin chemotherapy is a widely used treatment for various cancers, including breast, ovarian, and uterine cancers, among others. However, long-term use can cause nephrotoxicity side effects. Some citrus flavonoids have d
Externí odkaz:
https://doaj.org/article/cb7f48c11ea54dccbe0a702c2b82f678
Autor:
Samson A. Iwhiwhu, Ravi Kumar, Abdul H. Khan, Jeremiah M. Afolabi, Jada D. Williams, Julia E. de la Cruz, Adebowale Adebiyi
Publikováno v:
BMC Nephrology, Vol 25, Iss 1, Pp 1-11 (2024)
Abstract Background Pemetrexed is combined with cisplatin to treat cancer. Whether pemetrexed-cisplatin combination chemotherapy exacerbates cisplatin nephrotoxicity is unclear. Here, we investigated kidney injury in mice administered a non-lethal lo
Externí odkaz:
https://doaj.org/article/977e110c80094ac595a374bfca9bc070
Autor:
Bin Chen, Cheng Cheng, Yunhao Wu, Siyu Li, Mo Han, Le Zhen, Ying Peng, Suhan Guo, Kaidi Shen, Xia Gao, Renjie Chai, Guangji Wang, Fang Zhou
Publikováno v:
Acta Pharmaceutica Sinica B, Vol 14, Iss 10, Pp 4413-4430 (2024)
Ototoxicity and nephrotoxicity are the most prevalent side effects of aminoglycoside antibiotics (gentamicin, amikacin, neomycin) and platinum anti-tumor drugs (cisplatin, carboplatin). The inner ear and kidney share similarities in drug deposition a
Externí odkaz:
https://doaj.org/article/b706e7dca6f446dbb61c9606fa7738b9
Autor:
Victor Gueutin, Aurore Cardineau, Alexis Mathian, Antoine Lanot, François Comoz, Isabelle Brocheriou, Hassan Izzedine
Publikováno v:
BMC Nephrology, Vol 25, Iss 1, Pp 1-10 (2024)
Abstract Background Onconephrology is a growing discipline that aims to improve the management of patients with cancer and kidney disease. If kidney histology is an essential key, the anatomopathological data remain weak although essential to this co
Externí odkaz:
https://doaj.org/article/89cfd83f303540aa9af79f7f7dbb2af7
Publikováno v:
Регуляторные исследования и экспертиза лекарственных средств, Vol 14, Iss 4, Pp 448-462 (2024)
INTRODUCTION. The determination of nephrotoxicity markers is a useful and necessary step in the detection of renal injury in animal experiments; these markers help accurately localise organ damage. With multiple damaging agents, known nephrotoxicity
Externí odkaz:
https://doaj.org/article/53d85317f6654e4db4c4d6e44419c5c7
Autor:
Sercan Aydin, Seda Kahraman Aydin, Hasan Yavuz, Ayse Gul Ergonul, Tevfik Ilker Akcam, Kutsal Turhan, Alpaslan Cakan, Ufuk Cagirici
Publikováno v:
BMC Surgery, Vol 24, Iss 1, Pp 1-7 (2024)
Abstract Background The aim of combining hyperthermic intrathoracic chemotherapy (HITHOC) with surgery is to achieve local control in patients with pleural malignancies. Liver and kidney dysfunction resulting from this procedure have been reported in
Externí odkaz:
https://doaj.org/article/db167f833de24587b2a2f15fb06da388
Autor:
Hadiya Husain, Riaz Ahmad
Publikováno v:
Journal of Basic and Applied Zoology, Vol 85, Iss 1, Pp 1-12 (2024)
Abstract Background Pomegranate is considered as one of the oldest elixirs having various properties. Renal fibrosis is a preliminary sign of pathological degradation in most ailments related to kidney. Several efforts have been made for the discover
Externí odkaz:
https://doaj.org/article/472095626bb541b7b99eeeb3de656a0d