Zobrazeno 1 - 10
of 17
pro vyhledávání: '"neomarinone"'
Autor:
Khadija Hassan, Clara Chepkirui, Natalia Andrea Llanos-López, Josphat C. Matasyoh, Cony Decock, Yasmina Marin-Felix, Marc Stadler
Publikováno v:
Biomolecules, Vol 12, Iss 6, p 755 (2022)
A mycelial culture of the African basidiomycete Echinochaete cf. brachypora was studied for biologically active secondary metabolites, and four compounds were isolated from its crude extract derived from shake flask fermentations, using preparative h
Externí odkaz:
https://doaj.org/article/670936d2fdf44d09bd28429c92dd64a5
Akademický článek
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Publikováno v:
Chemistry - A European Journal. 15:910-916
The first total synthesis of (+)-neomarinone has been achieved by following a concise and convergent route using methyl (R)-lactate and (R)-3-methylcyclohexanone as chiral building blocks. Key steps of the synthesis are the stereocontrolled formation
Publikováno v:
Tetrahedron Letters. 48:6493-6495
A practical and efficient stereoselective synthesis of the side chain of neomarinone is reported. The synthesis was achieved in six steps (41% overall yield) from 2-methyl-2-cyclohexenone. The key step is a novel stereoselective 1,4-conjugate additio
Publikováno v:
ChemInform. 40
The first total synthesis of (+)-neomarinone has been achieved by following a concise and convergent route using methyl (R)-lactate and (R)-3-methylcyclohexanone as chiral building blocks. Key steps of the synthesis are the stereocontrolled formation
Publikováno v:
ChemInform. 39
A practical and efficient stereoselective synthesis of the side chain of neomarinone is reported. The synthesis was achieved in six steps (41% overall yield) from 2-methyl-2-cyclohexenone. The key step is a novel stereoselective 1,4-conjugate additio
Publikováno v:
Antonie van Leeuwenhoek. 87(1)
Drug discovery relies on the generation of large numbers of structurally diverse compounds from which a potential candidate can be identified. To this end, actinomycetes have often been exploited because of their ability to biosynthesize an impressiv
Publikováno v:
ChemInform. 35
[reaction: see text] The biosynthesis of the meroterpenoid neomarinone from a marine actinomycete was probed through feeding experiments with (13)C-labeled precursors. NMR characterization of [U-(13)C(6)]glucose-enriched neomarinone led to the struct
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