Zobrazeno 1 - 10
of 1 419
pro vyhledávání: '"nectin"'
Autor:
Popa-Navarro Xitlally, Avilés-Salas Alejandro, Hernández-Pedro Norma, Orozco-Morales Mario, Caballé-Pérez Enrique, Castillo-Ruiz Cesar, Lucio-Lozada José, Barrios-Bernal Pedro, Hernandez-Martinez Juan-Manuel, Arrieta Oscar
Publikováno v:
Journal of Translational Medicine, Vol 22, Iss 1, Pp 1-12 (2024)
Abstract Background CD155 is a transmembrane protein that inhibits antitumor immune response and represents a predictor of worse prognosis in non-small-cell lung cancer (NSCLC). However, it remains unexplored its association with clinical characteris
Externí odkaz:
https://doaj.org/article/1ebedd5e333e4f3c914155199daf9952
Autor:
Juan Carlos Barragan-Galvez, Araceli Hernandez-Flores, Orestes Lopez-Ortega, Adriana A. Rodriguez-Alvarez, Jose Luis Maravillas-Montero, Vianney Ortiz-Navarrete
Publikováno v:
Biochemistry and Biophysics Reports, Vol 39, Iss , Pp 101813- (2024)
CRTAM (Class-I MHC restricted T cell-associated molecule) is a member of the Nectin-like family, composed of two extracellular domains, one constant domain (IgC) and another variable domain (IgV), expressed in activated CD8 T cells, epithelial cells,
Externí odkaz:
https://doaj.org/article/acb1170682a540e28b619414ea4fe746
Publikováno v:
Frontiers in Oncology, Vol 14 (2024)
Externí odkaz:
https://doaj.org/article/a4084586bc1f442cb1a630e30a4b1a5b
Publikováno v:
Anais Brasileiros de Dermatologia, Vol 98, Iss 5, Pp 580-586 (2023)
Abstract Background Ectodermal dysplasia syndactyly syndrome 1 (EDSS1) is a rare hereditary disorder characterized by defects in teeth, hair, and nails in association with a fusion of the digits. Genetically, the disease phenotypes are caused by homo
Externí odkaz:
https://doaj.org/article/9da5350d3906421fa84ae0ce4524d6bc
Publikováno v:
OncoImmunology, Vol 12, Iss 1 (2023)
ABSTRACTThe use of antibodies to block inhibitory receptors, primarily anti-PD1 and CTLA4 (known as checkpoint therapy) revolutionized cancer treatment. However, despite these successes, the majority of cancer patients do not respond to the checkpoin
Externí odkaz:
https://doaj.org/article/2fd0a6e7c2a34bb6937509443052f335
Akademický článek
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Autor:
Stefanie Zschäbitz, Marie Mikuteit, Christine Stöhr, Edwin Herrmann, Iris Polifka, Abbas Agaimy, Lutz Trojan, Philipp Ströbel, Frank Becker, Christian Wülfing, Peter Barth, Michael Stöckle, Michael Staehler, Christian Stief, Axel Haferkamp, Markus Hohenfellner, Stefan Duensing, Stephan Macher-Göppinger, Bernd Wullich, Joachim Noldus, Walburgis Brenner, Frederik C. Roos, Bernhard Walter, Wolfgang Otto, Maximilian Burger, Andres Jan Schrader, Arndt Hartmann, Franziska Erlmeier, Sandra Steffens
Publikováno v:
Discover Oncology, Vol 13, Iss 1, Pp 1-12 (2022)
Abstract Background Nectin-4 contributes to tumor proliferation, lymphangiogenesis and angiogenesis in malignant tumors and is an emerging target in tumor therapy. In renal cell carcinoma (RCC) VEGF-directed tyrosine kinase inhibitors and checkpoint
Externí odkaz:
https://doaj.org/article/f48c4647fe714704ac7639eb9dc60db9
Autor:
Matteo Caforio, Nicola Tumino, Cristina Sorino, Isabella Manni, Stefano Di Giovenale, Giulia Piaggio, Simona Iezzi, Georgios Strimpakos, Elisabetta Mattei, Lorenzo Moretta, M. Fanciulli, Paola Vacca, Franco Locatelli, Valentina Folgiero
Publikováno v:
Frontiers in Immunology, Vol 14 (2023)
IntroductionAATF/Che-1 over-expression in different tumors is well known and its effect on tumorigenicity is mainly due to its central role demonstrated in the oncogenic pathways of solid tumors, where it controls proliferation and viability. The eff
Externí odkaz:
https://doaj.org/article/f5115f9bf1b74bdf9a69050d6bb081ea
Autor:
Hong‐Juan Liu, Meng‐Yun Deng, Yan‐Yan Zhu, De‐Ling Wu, Xiao‐Hui Tong, Li Li, Lei Wang, Fei Xu, Tong‐Sheng Wang
Publikováno v:
Animal Models and Experimental Medicine, Vol 4, Iss 4, Pp 351-358 (2021)
Abstract Background Oligoasthenospermia is one of the main causes of male infertility. Researchers usually use chemical drugs to directly damage germ cells to prepare oligoasthenospermia models, which disregards the adhesion and migration between spe
Externí odkaz:
https://doaj.org/article/1318431857534817bf93d4201513adae
Publikováno v:
Frontiers in Cell and Developmental Biology, Vol 10 (2022)
In the cochlear auditory epithelia, sensory hair and supporting cells are arranged in a checkerboard-like mosaic pattern, which is conserved across a wide range of species. The cell adhesion molecules nectin-1 and nectin-3 are required for this patte
Externí odkaz:
https://doaj.org/article/a051456c1feb40d4a9d8feae7f12a0eb