Zobrazeno 1 - 10
of 122
pro vyhledávání: '"nathalie cartier"'
Autor:
Emilie Audouard, Nicolas Khefif, Béatrix Gillet-Legrand, Fanny Nobilleau, Ouafa Bouazizi, Serena Stanga, Gaëtan Despres, Sandro Alves, Antonin Lamazière, Nathalie Cartier, Françoise Piguet
Publikováno v:
Pharmaceutics, Vol 16, Iss 6, p 756 (2024)
Rett syndrome (RTT) is a rare neurodevelopmental disorder caused by mutation in the X-linked gene methyl-CpG-binding protein 2 (Mecp2), a ubiquitously expressed transcriptional regulator. RTT results in mental retardation and developmental regression
Externí odkaz:
https://doaj.org/article/16c2313cb62a484b8456cc6cbf5ab1ee
Autor:
Marie‐Stéphane Aigrot, Clara Barthelemy, Sarah Moyon, Gaelle Dufayet‐Chaffaud, Leire Izagirre‐Urizar, Beatrix Gillet‐Legrand, Satoru Tada, Laura Bayón‐Cordero, Juan‐Carlos Chara, Carlos Matute, Nathalie Cartier, Catherine Lubetzki, Vanja Tepavčević
Publikováno v:
EMBO Molecular Medicine, Vol 14, Iss 8, Pp 1-17 (2022)
Abstract Preventing neurodegeneration‐associated disability progression in patients with multiple sclerosis (MS) remains an unmet therapeutic need. As remyelination prevents axonal degeneration, promoting this process in patients might enhance neur
Externí odkaz:
https://doaj.org/article/c1839741b7e847299f847e6b2eb4852c
Autor:
Karim Bey, Johan Deniaud, Laurence Dubreil, Béatrice Joussemet, Joseph Cristini, Carine Ciron, Juliette Hordeaux, Morwenn Le Boulc’h, Kevin Marche, Maud Maquigneau, Michaël Guilbaud, Rosalie Moreau, Thibaut Larcher, Jack-Yves Deschamps, Marion Fusellier, Véronique Blouin, Caroline Sevin, Nathalie Cartier, Oumeya Adjali, Patrick Aubourg, Philippe Moullier, Marie-Anne Colle
Publikováno v:
Molecular Therapy: Methods & Clinical Development, Vol 17, Iss , Pp 771-784 (2020)
The identification of the most efficient method for whole central nervous system targeting that is translatable to humans and the safest route of adeno-associated virus (AAV) administration is a major concern for future applications in clinics. Addit
Externí odkaz:
https://doaj.org/article/a0aedb1aca064422b991e72f09f1cc8d
Autor:
Clévio Nóbrega, André Conceição, Rafael G. Costa, Rebekah Koppenol, Raquel L. Sequeira, Ricardo Nunes, Sara Carmo-Silva, Adriana Marcelo, Carlos A. Matos, Sandrine Betuing, Jocelyne Caboche, Nathalie Cartier, Sandro Alves
Publikováno v:
BMC Research Notes, Vol 13, Iss 1, Pp 1-9 (2020)
Abstract Objective Compromised brain cholesterol turnover and altered regulation of brain cholesterol metabolism have been allied with some neurodegenerative diseases, including Huntington’s disease (HD). Following our previous studies in HD, in th
Externí odkaz:
https://doaj.org/article/34bd3c232ee348b6aee607030541dff4
Autor:
Irina A. Pikuleva, Nathalie Cartier
Publikováno v:
Frontiers in Aging Neuroscience, Vol 13 (2021)
Cholesterol, an essential component of the brain, and its local metabolism are involved in many neurodegenerative diseases. The blood-brain barrier is impermeable to cholesterol; hence, cholesterol homeostasis in the central nervous system represents
Externí odkaz:
https://doaj.org/article/782f336f32774b2d824aeea6c27b3843
Publikováno v:
Frontiers in Bioengineering and Biotechnology, Vol 9 (2021)
Improving a drug delivery system is critical to treat central nervous system disorders. Here we studied an innovative approach based on implantation of a wireless-powered cell-based device in mice. This device, coupling biologic material and electron
Externí odkaz:
https://doaj.org/article/3e87c195de154062aad2fb38c0931bc6
Autor:
Benoît Souchet, Mickael Audrain, Jean Marie Billard, Julien Dairou, Romain Fol, Nicola Salvatore Orefice, Satoru Tada, Yuchen Gu, Gaelle Dufayet-Chaffaud, Emmanuelle Limanton, François Carreaux, Jean-Pierre Bazureau, Sandro Alves, Laurent Meijer, Nathalie Janel, Jérôme Braudeau, Nathalie Cartier
Publikováno v:
Acta Neuropathologica Communications, Vol 7, Iss 1, Pp 1-15 (2019)
Abstract Recent evidences suggest the involvement of DYRK1A (dual specificity tyrosine phosphorylation-regulated kinase 1 A) in Alzheimer’s disease (AD). Here we showed that DYRK1A undergoes a proteolytic processing in AD patients hippocampus witho
Externí odkaz:
https://doaj.org/article/78eb540db4c7476bab36dc4843c783a9
Autor:
Emilie Audouard, Valentin Oger, Béatrix Meha, Nathalie Cartier, Caroline Sevin, Françoise Piguet
Publikováno v:
Frontiers in Molecular Neuroscience, Vol 14 (2021)
Metachromatic leukodystrophy (MLD) is a lysosomal storage disorder characterized by accumulation of sulfatides in both glial cells and neurons. MLD results from an inherited deficiency of arylsulfatase A (ARSA) and myelin degeneration in the central
Externí odkaz:
https://doaj.org/article/5c4e8a50d7044a1cb21a229a411d1dbf
Autor:
Sophie Ayciriex, Fathia Djelti, Sandro Alves, Anne Regazzetti, Mathieu Gaudin, Jennifer Varin, Dominique Langui, Ivan Bièche, Eloise Hudry, Delphine Dargère, Patrick Aubourg, Nicolas Auzeil, Olivier Laprévote, Nathalie Cartier
Publikováno v:
Frontiers in Molecular Neuroscience, Vol 10 (2017)
Impairment in cholesterol metabolism is associated with many neurodegenerative disorders including Alzheimer's disease (AD). However, the lipid alterations underlying neurodegeneration and the connection between altered cholesterol levels and AD rema
Externí odkaz:
https://doaj.org/article/36701410ec094cada7a18c8bf864ef5d
Autor:
Benjamin Séri, Ange Koffi, Christine Danel, Timothée Ouassa, Marcel-Angora Blehoué, Eric Ouattara, Jeanne-d'Arc Assemien, Jean-Marie Masumbuko, Patrick Coffie, Nathalie Cartier, Arnaud Laurent, Gilles Raguin, Denis Malvy, Thérèse N'Dri-Yoman, Serge P Eholié, Serge K Domoua, Xavier Anglaret, Marie-Catherine Receveur
Publikováno v:
PLoS ONE, Vol 12, Iss 7, p e0181995 (2017)
In Côte d'Ivoire, a TB prison program has been developed since 1999. This program includes offering TB screening to prisoners who show up with TB symptoms at the infirmary. Our objective was to estimate the prevalence of pulmonary TB among inmates a
Externí odkaz:
https://doaj.org/article/6e02c42478fa490ba5870929c8b42928