Zobrazeno 1 - 10
of 977
pro vyhledávání: '"nasal epithelial cells"'
Publikováno v:
Veterinary Research, Vol 55, Iss 1, Pp 1-16 (2024)
Abstract The nasal mucosa forms a critical barrier against the invasion of respiratory pathogens. Composed of a heterogeneous assortment of cell types, the nasal mucosa relies on the unique characteristics and complex intercellular dynamics of these
Externí odkaz:
https://doaj.org/article/58b6789c07e9463abb2affaf0137d3f1
Autor:
George D. Vavougios, Theodoros Mavridis, Triantafyllos Doskas, Olga Papaggeli, Pelagia Foka, Georgios Hadjigeorgiou
Publikováno v:
Current Issues in Molecular Biology, Vol 46, Iss 5, Pp 4565-4579 (2024)
Type I interferon signaling (IFN-I) perturbations are major drivers of COVID-19. Dysregulated IFN-I in the brain, however, has been linked to both reduced cognitive resilience and neurodegenerative diseases such as Alzheimer’s. Previous works from
Externí odkaz:
https://doaj.org/article/1217637270d84b0091a813a4d6539576
Autor:
Jing Zhou, Jiao Zhou, Ruowu Liu, Yafeng Liu, Juan Meng, Qiao Wen, Yirui Luo, Shixi Liu, Huabin Li, Luo Ba, Jintao Du
Publikováno v:
Frontiers in Immunology, Vol 15 (2024)
BackgroundAlthough oxidative stress is involved in the pathophysiological process of chronic rhinosinusitis with nasal polyps (CRSwNP), the specific underlying mechanism is still unclear. Whether antioxidant therapy can treat CRSwNP needs further inv
Externí odkaz:
https://doaj.org/article/9ab8445652e84fcfa7f67c9c1f5ec2db
Publikováno v:
Heliyon, Vol 10, Iss 5, Pp e27688- (2024)
Maintaining tight junction integrity significantly contributes to epithelial barrier function. If the barrier function is destroyed, the permeability of the cells increases, and the movement of the pathogens is promoted, thereby further increasing th
Externí odkaz:
https://doaj.org/article/4b2eceb76d104565aa97effea5d19262
Autor:
Shwetha Chandrasekhar, Siying Lin, Neringa Jurkute, Kathryn Oprych, Leire Estramiana Elorrieta, Elena Schiff, Samantha Malka, Genevieve Wright, Michel Michaelides, Omar A. Mahroo, Andrew R. Webster, Gavin Arno
Publikováno v:
Cells, Vol 13, Iss 15, p 1261 (2024)
Biallelic variants in USH2A are associated with retinitis pigmentosa (RP) and Type 2 Usher Syndrome (USH2), leading to impaired vision and, additionally, hearing loss in the latter. Although the introduction of next-generation sequencing into clinica
Externí odkaz:
https://doaj.org/article/9f8300908b4346948f247decb549375c
Autor:
Ji-Sun Kim, Hyunsu Choi, Jeong-Min Oh, Sung Won Kim, Soo Whan Kim, Byung Guk Kim, Jin Hee Cho, Joohyung Lee, Dong Chang Lee
Publikováno v:
Toxics, Vol 12, Iss 6, p 407 (2024)
Pyroptosis represents a type of cell death mechanism notable for its cell membrane disruption and the subsequent release of proinflammatory cytokines. The Nod-like receptor family pyrin domain containing inflammasome 3 (NLRP3) plays a critical role i
Externí odkaz:
https://doaj.org/article/cf548c13845248b3930091688df414bc
Autor:
Peter Ertl, Tibor Wladimir, Drago Sticker, Patrick Schuller, Mario Rothbauer, Georg Wieselthaler, Martin Frauenlob
Publikováno v:
Biosensors, Vol 14, Iss 5, p 253 (2024)
Heart failure represents a primary cause of hospitalization and mortality in both developed and developing countries, often necessitating heart transplantation as the only viable recovery path. Despite advances in transplantation medicine, organ reje
Externí odkaz:
https://doaj.org/article/029b6acab519446bb5c94367499ebd1b
Autor:
Bingjie Hu, Jasper Fuk-Woo Chan, Yuanchen Liu, Huan Liu, Yan-Xia Chen, Huiping Shuai, Ye-Fan Hu, Madeline Hartnoll, Li Chen, Yao Xia, Jing-Chu Hu, Terrence Tsz-Tai Yuen, Chaemin Yoon, Yuxin Hou, Xiner Huang, Yue Chai, Tianrenzheng Zhu, Jialu Shi, Yang Wang, Yixin He, Jian-Piao Cai, Jie Zhou, Shuofeng Yuan, Jinxia Zhang, Jian-Dong Huang, Kwok-Yung Yuen, Kelvin Kai-Wang To, Bao-Zhong Zhang, Hin Chu
Publikováno v:
EBioMedicine, Vol 99, Iss , Pp 104916- (2024)
Summary: Background: Earlier Omicron subvariants including BA.1, BA.2, and BA.5 emerged in waves, with a subvariant replacing the previous one every few months. More recently, the post-BA.2/5 subvariants have acquired convergent substitutions in spik
Externí odkaz:
https://doaj.org/article/d9b69a5d5c864724b9fce2300ab51b5e
Publikováno v:
Allergology International, Vol 72, Iss 1, Pp 161-168 (2023)
Background: Patients with eosinophilic chronic rhinosinusitis (ECRS) respond poorly to many treatment modalities. Overproduction of periostin in the nasal mucosa is reported to contribute to polyp formation. This study examined periostin levels in pa
Externí odkaz:
https://doaj.org/article/e85ee98eb54b4406991a3a611898c245
Autor:
Iuliia Kalashnyk-Vakulenko, Galina Gubina-Vakulyck, Anatolii Onishchenko, Oksana Nakonechna, Tatyana Gorbach, Viktoriya Tkachenko, Anton Tkachenko
Publikováno v:
Ķazaķstannyṇ Klinikalyķ Medicinasy, Vol 19, Iss 6, Pp 63-67 (2022)
Aim: To evaluate expression of anti-apoptotic Bcl-2 protein in the nasal tissue and its levels in blood serum of patients with chronic rhinosinusitis with (CRSwNP) and without nasal polyps (CRSsNP). Material and methods: Expression of Bcl-2 in the si
Externí odkaz:
https://doaj.org/article/7354e3294969420085b991e3b1e63cd4