Design, synthesis and cholinesterase inhibitory properties of new oxazole benzylamine derivatives

Autor: Ivana Šagud, Nikolina Maček Hrvat, Ana Grgičević, Tena Čadež, Josipa Hodak, Milena Dragojević, Kornelija Lasić, Zrinka Kovarik, Irena Škorić

Publikováno v: Journal of Enzyme Inhibition and Medicinal Chemistry, Vol 35, Iss 1, Pp 460-467 (2020)

The enzymes acetylcholinesterase (AChE) and butyrylcholinesterase (BChE) are primary targets in attenuating the symptoms of neurodegenerative diseases. Their inhibition results in elevated concentrations of the neurotransmitter acetylcholine which su

Externí odkaz: https://doaj.org/article/eac30c3e5b384c42be6a7deff70a38fa

NAFTOIMIDAZÓIS E NAFTOXAZÓIS - PROMISSORES COMPONENTES DE SISTEMAS TERANÓSTICOS

Autor: Santos,Victória Laysna dos Anjos, Guimarães,Délis Galvão, Nishimura,Rodolfo Hideki Vicente, Rolim,Larissa Araújo, Gonsalves,Arlan de Assis, Araújo,Cleônia Roberta Melo

Publikováno v: Química Nova v.45 n.5 2022
Química Nova
Sociedade Brasileira de Química (SBQ)
instacron:SBQ

Theranostic can be used to define therapeutic and imaging agents in a system. It is consisting of four components: signal emitter, therapeutic agent, targeting ligand and carrier. Naphthoimidazole and naphthoxazole are extended aromatic systems, and

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=od______3056::49ee244a3e9bd610b392122ae0e755c1
http://old.scielo.br/scielo.php?script=sci_arttext&pid=S0100-40422022000500560

Design, synthesis and cholinesterase inhibitory properties of new oxazole benzylamine derivatives

Autor: Ana Grgičević, Zrinka Kovarik, Ivana Šagud, Josipa Hodak, Tena Čadež, Irena Škorić, Kornelija Lasić, Nikolina Maček Hrvat, Milena Dragojević

Publikováno v: Journal of Enzyme Inhibition and Medicinal Chemistry
Journal of Enzyme Inhibition and Medicinal Chemistry, Vol 35, Iss 1, Pp 460-467 (2020)

The enzymes acetylcholinesterase (AChE) and butyrylcholinesterase (BChE) are primary targets in attenuating the symptoms of neurodegenerative diseases. Their inhibition results in elevated concentrations of the neurotransmitter acetylcholine which su

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d1ad6f120a2f66be3fdea6300f3f0d34
https://doi.org/10.1080/14756366.2019.1707197

Antiinflammatory and antiproliferative activity of naphthoxazole, fused hetero-benzoxazole and bridged benzobicyclic photoproducts

Autor: Martina Bosnar, Ivana Šagud, Irena Škorić, Ana Ratković, Vanja Kelava, Ivo Zlatar, Matea Cedilak

Publikováno v: Croatica Chemica Acta
Volume 92
Issue 2

Biological activity of naphthoxazoles, fused hetero-benzoxazoles and benzobicyclo[3.2.1]-derivatives was investigated in proliferation and inflammation based assays. The tested compounds were prepared by photocylization or photocycloaddition reaction

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::23f55bef71745e8b5cc495399c645408
https://doi.org/10.5562/cca3530

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