Zobrazeno 1 - 10
of 551
pro vyhledávání: '"nanovesicle"'
Autor:
Yuxuan Liu, Fuxu Yang, Zhimin Li, Ting Wang, Yeteng Mu, Yuxin Fan, Han Xue, Xiuli Hu, Xingang Guan, Hongxia Feng
Publikováno v:
Frontiers in Pharmacology, Vol 15 (2024)
Immune checkpoint inhibitors (ICIs) have revolutionized cancer treatment, demonstrating unprecedented efficacy against advanced cancers. However, their clinical applications are significantly hampered by low overall response rates. Dual blockade of t
Externí odkaz:
https://doaj.org/article/928e4854d0924605acb7e457b9bde273
Publikováno v:
Advanced Science, Vol 11, Iss 40, Pp n/a-n/a (2024)
Abstract Liver fibrosis, arising from factors such as viral infections or metabolic disorders, represents an ongoing global health challenge and is a major risk factor for hepatocellular carcinoma. Unfortunately, there are no clinically approved drug
Externí odkaz:
https://doaj.org/article/711b26f824a448709ab6473ac5f19408
Autor:
Manxiu Huai, Yingjie Wang, Junhao Li, Jiaxing Pan, Fang Sun, Feiyu Zhang, Yi Zhang, Leiming Xu
Publikováno v:
Journal of Nanobiotechnology, Vol 22, Iss 1, Pp 1-17 (2024)
Abstract Imperceptible examination and unideal treatment effect are still intractable difficulties for the clinical treatment of pancreatic ductal adenocarcinoma (PDAC). At present, despite 5-fluorouracil (5-FU), as a clinical first-line FOLFIRINOX c
Externí odkaz:
https://doaj.org/article/4cfd0131ed7f45a695d4fe096f464496
Autor:
Suke Deng, Jiacheng Wang, Yan Hu, Yajie Sun, Xiao Yang, Bin Zhang, Yue Deng, Wenwen Wei, Zhanjie Zhang, Lu Wen, You Qin, Fang Huang, Yuhan Sheng, Chao Wan, Kunyu Yang
Publikováno v:
Journal of Nanobiotechnology, Vol 22, Iss 1, Pp 1-16 (2024)
Abstract Immunotherapy has revolutionized the treatment of cancer. However, its efficacy remains to be optimized. There are at least two major challenges in effectively eradicating cancer cells by immunotherapy. Firstly, cancer cells evade immune cel
Externí odkaz:
https://doaj.org/article/30532cda56f148609497327dcdd8f093
Publikováno v:
Metabolism Open, Vol 22, Iss , Pp 100266- (2024)
Externí odkaz:
https://doaj.org/article/ab177b8134cb4e8f92c3ea9eff297fd1
Publikováno v:
Nanomaterials, Vol 14, Iss 21, p 1727 (2024)
Aptamers are short DNA or RNA sequences that adopt 3D structures and can bind to protein targets with high binding affinity and specificity. Aptamers exhibit excellent tissue penetration, are inexpensive to produce, and can be internalized by cells.
Externí odkaz:
https://doaj.org/article/002aac8706924d29aa1181ed0afdf6fe
Publikováno v:
Heliyon, Vol 10, Iss 9, Pp e30630- (2024)
Exosomes are extracellular vesicles comprising bilayer phospholipid membranes and are secreted by eukaryotic cells. They are released via cellular exocytosis, contain DNA, RNA, proteins, and other substances, and participate in various cellular commu
Externí odkaz:
https://doaj.org/article/f4c2fa195b40444b85ebe02edd896acd
Publikováno v:
Acta Pharmaceutica Sinica B, Vol 13, Iss 5, Pp 1789-1827 (2023)
Cellular nanovesicles which are referred to as cell-derived, nanosized lipid bilayer structures, have emerged as a promising platform for regulating immune responses. Owing to their outstanding advantages such as high biocompatibility, prominent stru
Externí odkaz:
https://doaj.org/article/b612a0973d0e4a3cac7d8c1768a1e680
Autor:
Zuoxu Hou, Xiao Wang, Zefeng Yang, Zhiwei Deng, Jin Zhang, Jintao Zhong, Shanrui Liu, Yuanyuan Hu, Hongxun Sang
Publikováno v:
Journal of Functional Foods, Vol 108, Iss , Pp 105734- (2023)
Plant-derived exosome-like nanovesicles carry a variety of bioactive substances and have multiple health benefits. Pomegranate (Punica granatum) is a popular fruit with hepatoprotective effects. However, the effects of pomegranate-derived exosome-lik
Externí odkaz:
https://doaj.org/article/d8027c7b51ba46c0af6df52fb3c01f8f
Publikováno v:
Asian Journal of Pharmaceutical Sciences, Vol 17, Iss 6, Pp 924-937 (2022)
Drug resistance is accountable for the inadequate outcome of chemotherapy in clinics. The newly emerging role of nitric oxide (NO) to conquer drug resistance has been recognized as a potential strategy. However, it remains a great challenge to realiz
Externí odkaz:
https://doaj.org/article/1eceeb444ce64c31b3be35ef11e1aa70