Zobrazeno 1 - 10
of 107
pro vyhledávání: '"nanos3"'
Publikováno v:
Cell & Bioscience, Vol 13, Iss 1, Pp 1-14 (2023)
Abstract Background Mouse embryonic stem cells (mESCs) not only retain the property of self-renewal but also have the ability to develop into primordial germ cell-like cells (PGCLCs). However, knowledge about the mechanisms of transcriptional regulat
Externí odkaz:
https://doaj.org/article/990aa26e5871452089c7718a3e5ac361
Autor:
Maci L. Mueller, Bret R. McNabb, Joseph R. Owen, Sadie L. Hennig, Alba V. Ledesma, Mitchell L. Angove, Alan J. Conley, Pablo J. Ross, Alison L. Van Eenennaam
Publikováno v:
Frontiers in Genome Editing, Vol 5 (2023)
NANOS3 is expressed in migrating primordial germ cells (PGCs) to protect them from apoptosis, and it is known to be a critical factor for germline development of both sexes in several organisms. However, to date, live NANOS3 knockout (KO) cattle have
Externí odkaz:
https://doaj.org/article/bb5e53530cf64fdbaedd03b77d8af4c0
Autor:
Yuhei KOGASAKA, Sho MURAKAMI, Shiro YAMASHITA, Daisuke KIMURA, Yoshinori FURUMOTO, Kana IGUCHI, Yutaka SENDAI
Publikováno v:
The Journal of Reproduction and Development, Vol 68, Iss 6, Pp 361-368 (2022)
NANOS3 is an evolutionarily conserved gene expressed in primordial germ cells that is important for germ cell development. Germ cell deletion by NANOS3 knockout has been reported in several mammalian species, but its function in pigs is unclear. In t
Externí odkaz:
https://doaj.org/article/ab56f55249064973a642dc2030a08994
Autor:
Meiqing Yao, Qin He, Manqiong Yang, Zhixiang Wu, Ying Li, Min Kong, Zhijuan Kang, Lu Yi, Yanan Hu, Lihua Huang, Zhuoying Li, Zuocheng Yang
Publikováno v:
Frontiers in Pediatrics, Vol 10 (2022)
BackgroundKawasaki disease (KD) is an acute systemic vasculitis of unknown etiology. The rs8108402 C/T single nucleotide polymorphism (SNP) is located in the promoter region of miR-181-c/d gene and the intron of Nanos3 gene. The miR-181 family contri
Externí odkaz:
https://doaj.org/article/93617e33e60a4935b0ff3df71fcff25c
Autor:
Liu Qiqi, He Junlin, Chen Xuemei, Hong Yi, Li Fangfang, Geng Yanqing, Zhang Yan, Jones Lamptey, Chen Zhuxiu, Liu Fangfei, Wang Yingxiong, Mu Xinyi
Publikováno v:
Ecotoxicology and Environmental Safety, Vol 236, Iss , Pp 113480- (2022)
The primordial follicle pool established in early life determines the ovarian reserve in the female reproductive lifespan. Premature exhaustion of primordial follicles contributes to primary ovarian insufficiency (POI), that is dependent by the initi
Externí odkaz:
https://doaj.org/article/68103d9991144a549db23efe140c7308
Publikováno v:
Biology Open, Vol 11, Iss 4 (2022)
In the mouse testis, sperm originate from spermatogonial stem cells (SSCs). SSCs give rise to spermatogonial progenitors, which expand their population until entering the differentiation process that is precisely regulated by a fixed time-scaled prog
Externí odkaz:
https://doaj.org/article/46b74000a2e948a6bdf1b75a30a74b8c
Publikováno v:
Cancer Cell International, Vol 20, Iss 1, Pp 1-14 (2020)
Abstract Background Radiotherapy, chemotherapy, and surgery have made crucial strides in glioblastoma treatment, yet they often fail; thus, new treatment and new detection methods are needed. Aberrant expression of Nanos3 has been functionally associ
Externí odkaz:
https://doaj.org/article/28d3fb8a13c14169bbcc1b416f054a57
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