Zobrazeno 1 - 10
of 1 419
pro vyhledávání: '"nanodrug"'
Autor:
Dingkun Lu, Xiaohan Fan
Publikováno v:
Journal of Nanobiotechnology, Vol 22, Iss 1, Pp 1-25 (2024)
Abstract Cardiac arrhythmia, a disorder of abnormal electrical activity of the heart that disturbs the rhythm of the heart, thereby affecting its normal function, is one of the leading causes of death from heart disease worldwide and causes millions
Externí odkaz:
https://doaj.org/article/8118dc9081d8483683f7650ba6da3eba
Publikováno v:
International Journal of Nanomedicine, Vol Volume 19, Pp 7493-7508 (2024)
Peigang Zhang,1,2,* Lingling Zheng,1,3,4,* Xiaorui Zhang,1,3 Miao Liu,1,3 Mingli Li,2 Mengting Zhang,1 Jian-Lin Wu,4 Martin MF Choi,5 Wei Bian1– 3 1Department of Medical Chemistry, School of Basic Medical Science, Shanxi Medical University,
Externí odkaz:
https://doaj.org/article/7cd0dc0be1554871a48062d962ae5a44
Autor:
Ping Yu, Tanwei Gu, Yueyang Rao, Weimin Liang, Xi Zhang, Huanguo Jiang, Jindi Lu, Jianglian She, Jianmin Guo, Wei Yang, Yonghong Liu, Yingfeng Tu, Lan Tang, Xuefeng Zhou
Publikováno v:
Acta Pharmaceutica Sinica B, Vol 14, Iss 7, Pp 3232-3250 (2024)
Insufficient therapeutic strategies for acute kidney injury (AKI) necessitate precision therapy targeting its pathogenesis. This study reveals the new mechanism of the marine-derived anti-AKI agent, piericidin glycoside S14, targeting peroxiredoxin 1
Externí odkaz:
https://doaj.org/article/d25b34968aac42819ebddcb13d0f09a5
Autor:
Jinfeng Liao, Qingjia Gu, Zheng Liu, Hailian Wang, Xian Yang, Rongkai Yan, Xiaofeng Zhang, Siyuan Song, Lebin Wen, Yi Wang
Publikováno v:
Frontiers in Pharmacology, Vol 15 (2024)
As global population and lifestyles change, osteoarthritis (OA) is becoming a major healthcare challenge world. OA, a chronic condition characterized by inflammatory and degeneration, often present with joint pain and can lead to irreversible disabil
Externí odkaz:
https://doaj.org/article/724172b74f0841a39a4dbc418985e12f
Autor:
Yusuf Doğan, Cem Öziç, Erdal Ertaş, Ayşe Baran, Gvozden Rosic, Dragica Selakovic, Aziz Eftekhari
Publikováno v:
Frontiers in Chemistry, Vol 12 (2024)
Cancer is a major disease that affects millions of people around the world every year. It affects individuals of all ages, races, and backgrounds. Since drugs used to treat cancer cannot distinguish between cancerous and healthy cells, they cause sys
Externí odkaz:
https://doaj.org/article/50d5230018f94d40b4ca1393527bdab0
Autor:
Venkatachalababu Janitri, Kandasamy Nagarajan ArulJothi, Vijay Murali Ravi Mythili, Sachin Kumar Singh, Parteek Prasher, Gaurav Gupta, Kamal Dua, Rakshith Hanumanthappa, Karthikeyan Kaliappan, Krishnan Anand
Publikováno v:
MedComm, Vol 5, Iss 10, Pp n/a-n/a (2024)
Abstract Patient‐derived xenografts (PDX) involve transplanting patient cells or tissues into immunodeficient mice, offering superior disease models compared with cell line xenografts and genetically engineered mice. In contrast to traditional cell
Externí odkaz:
https://doaj.org/article/2b496cd3b52c49caa830372bd555c313
Autor:
Guangyao Li, Shuyi Zhang, Yitan Zou, Hongru Ai, Xinya Zheng, Kewen Qian, Changhai Lei, Wenyan Fu
Publikováno v:
Frontiers in Immunology, Vol 15 (2024)
Exosomes are found in various tissues of the body and carry abundant contents including nucleic acids, proteins, and metabolites, which continuously flow between cells of various tissues and mediate important intercellular communication. In addition,
Externí odkaz:
https://doaj.org/article/3647f5f043cc4c04a6486fb7b0d6f46d
Autor:
Yuying Zhao, Hanxu Tan, Juping Zhang, Dandan Zhan, Bowen Yang, Shicui Hong, Bo Pan, Neng Wang, Tongkai Chen, Yafei Shi, Zhiyu Wang
Publikováno v:
Journal of Nanobiotechnology, Vol 22, Iss 1, Pp 1-22 (2024)
Abstract Endocrine therapy is standard for hormone receptor–positive (HR+) breast cancer treatment. However, current strategies targeting estrogen signaling pay little attention to estradiol metabolism in the liver and is usually challenged by trea
Externí odkaz:
https://doaj.org/article/b6dee3d4f2c341358ffc74671102f069
Publikováno v:
Zhongliu Fangzhi Yanjiu, Vol 51, Iss 2, Pp 134-139 (2024)
Osimertinib is an irreversible third representative epidermal growth factor receptor tyrosine kinase inhibitor (EGFR-TKI) for the treatment of non-small cell lung cancer (NSCLC) with T790M resistance and classical EGFR mutations. However, the therape
Externí odkaz:
https://doaj.org/article/5095da3917c04130b3619c3aae5d4288
Autor:
Haichao Yu, Zelong Song, Jie Yu, Boyuan Ren, Yuan Dong, Yonggang You, Zhen Zhang, Chengqi Jia, Yunpeng Zhao, Xuhui Zhou, Haifeng Sun, Xuesong Zhang
Publikováno v:
Bioactive Materials, Vol 32, Iss , Pp 164-176 (2024)
Osteoarthritis (OA) has emerged as a significant health concern among the elderly population, with increasing attention paid to ferroptosis-induced OA in recent years. However, the prolonged use of nonsteroidal anti-inflammatory drugs or corticostero
Externí odkaz:
https://doaj.org/article/ac3a78d93e1b4f5294f937f07a6443e5