Single-cell transcriptomics reveals age-resistant maintenance of cell identities, stem cell compartments and differentiation trajectories in long-lived naked mole-rats skin

Autor: Aleksandra Savina, Thierry Jaffredo, Frederic Saldmann, Chris G. Faulkes, Philippe Moguelet, Christine Leroy, Delphine Del Marmol, Patrice Codogno, Lucy Foucher, Antoine Zalc, Mélanie Viltard, Gérard Friedlander, Selim Aractingi, Romain H. Fontaine

Publikováno v: Aging
Aging, 2023, 14 (9), pp.3728-3756. ⟨10.18632/aging.204054⟩
Savina, A, Jaffredo, T, Saldmann, F, Faulkes, C G, Moguelet, P, Leroy, C, Marmol, D D, Codogno, P, Foucher, L, Zalc, A, Viltard, M, Friedlander, G, Aractingi, S & Fontaine, R H 2022, ' Single-cell transcriptomics reveals age-resistant maintenance of cell identities, stem cell compartments and differentiation trajectories in long-lived naked mole-rats skin ', Aging, vol. 14, no. 9, pp. 3728-3756 . https://doi.org/10.18632/aging.204054

International audience; Naked mole-rats (NMR) are subterranean rodents characterized by an unusual longevity coupled with an unexplained resistance to aging. In the present study, we performed extensive in situ analysis and single-cell RNA-sequencing

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9802da7899c2cf1b28075a1661989157
https://doi.org/10.18632/aging.204054