Zobrazeno 1 - 10
of 1 101
pro vyhledávání: '"n6-methyladenosine(m6a)"'
Autor:
Yuanyuan Liu, Jian Li, Chenhui Wang, Jiangbo Li, Kai Luo, Kang Tao, Yuan Tian, Xiang Song, Zhifang Zhai, Yuandong Tao, Jia You, Lihua Wu, Wenqian Li, Yuanyuan Jiao, Rongya Yang, Mingwang Zhang
Publikováno v:
BMC Biology, Vol 22, Iss 1, Pp 1-13 (2024)
Abstract Background N6-Methyladenosine (m6A) methylation, a common form of RNA modification, play an important role in the pathogenesis of various diseases and in the ontogeny of organisms. Nevertheless, the precise function of m6A methylation in pho
Externí odkaz:
https://doaj.org/article/312208779c9a436691f80afbddde0212
Publikováno v:
Non-coding RNA Research, Vol 9, Iss 3, Pp 913-920 (2024)
Myeloid-derived suppressor cells (MDSCs) are closely related to the occurrence and development of many cancers, but the specific mechanism is not fully understood. It has been found that N6-methyladenosine (m6A) plays a key role in RNA metabolism, bu
Externí odkaz:
https://doaj.org/article/14c59d51407146d1823c6f866b2ddb7c
Publikováno v:
Cell & Bioscience, Vol 14, Iss 1, Pp 1-20 (2024)
Abstract N6-methyladenosine (m6A) is dynamically regulated by methyltransferases (termed “writers”) and demethylases (referred to as “erasers”), facilitating a reversible modulation. Changes in m6A levels significantly influence cellular func
Externí odkaz:
https://doaj.org/article/5b7eca434a144816aca04265d217c2ae
Autor:
Fei Huang, Yuan Ren, Yufei Hua, Ying Wang, Ruomeng Li, Ning Ji, Xin Zeng, Ding Bai, Qianming Chen, Xikun Zhou, Junjie Wu, Jing Li
Publikováno v:
Molecular Biomedicine, Vol 5, Iss 1, Pp 1-17 (2024)
Abstract miRNA has emerged as a crucial regulator in various of pathological and physiological processes, yet its precise mechanism of action the detailed mechanism of their action in Head and neck squamous cell carcinoma (HNSCC) remains incompletely
Externí odkaz:
https://doaj.org/article/24b6f07fe4af404e876157a7a83ca5cd
Autor:
Bin Peng, Yinglin Lin, Gao Yi, Mingzhen Lin, Yao Xiao, Yezhenghong Qiu, Wenxia Yao, Xinke Zhou, Zhaoyu Liu
Publikováno v:
Scientific Reports, Vol 14, Iss 1, Pp 1-19 (2024)
Abstract The epigenetic regulation of N6-methyladenosine (m6A) has attracted considerable interest in tumor research, but the potential roles of m6A regulator-related genes, remain largely unknown within the context of gastric cancer (GC) and tumor m
Externí odkaz:
https://doaj.org/article/3965a63e12bc4e6eb94a127f2baceff7
Autor:
Xiaolan Zhu, Wenxin Li, Minjun Lu, Junyu Shang, Jiamin Zhou, Li Lin, Yueqin Liu, Jie Xing, Mengxue Zhang, Shijie Zhao, Jingjing Lu, Xuyan Shi
Publikováno v:
Journal of Nanobiotechnology, Vol 22, Iss 1, Pp 1-21 (2024)
Abstract Background Premature ovarian insufficiency (POI) is an important cause of female infertility and seriously impacts the physical and psychological health of patients. Human umbilical cord mesenchymal stem cell-derived exosomes (HucMSCs-Exs, H
Externí odkaz:
https://doaj.org/article/ad349b1aeaa4446d99e353c0019ecabe
Publikováno v:
Discover Oncology, Vol 15, Iss 1, Pp 1-14 (2024)
Abstract Colorectal cancer is a leading cause of cancer-related mortality worldwide. Traditionally, colorectal cancer has been recognized as a disease caused by genetic mutations. However, recent studies have revealed the significant role of epigenet
Externí odkaz:
https://doaj.org/article/924ae2f767e34e4e981d3f4876ce1457
Autor:
Ying Li, Peidong Miao, Fang Li, Jinsong Huang, Lijun Fan, Qiaoling Chen, Yunan Zhang, Feng Yan, Yan Gao
Publikováno v:
BMC Psychiatry, Vol 24, Iss 1, Pp 1-9 (2024)
Abstract Objective To find the relationship between N6-methyladenosine (m6A) genes and Major Depressive Disorder (MDD). Methods Differential expression of m6A associated genes between normal and MDD samples was initially identified. Subsequent analys
Externí odkaz:
https://doaj.org/article/62f8f058e3374b078540cd5f651659a8
Publikováno v:
Immunity, Inflammation and Disease, Vol 12, Iss 8, Pp n/a-n/a (2024)
Abstract Background N6‐methyladenosine (m6A) has been identified as the most abundant modification of RNA molecules and the aberrant m6A modifications have been associated with the development of autoimmune diseases. However, the role of m6A modifi
Externí odkaz:
https://doaj.org/article/c74aadb09214407ebc0f7a6d9adbab94
Autor:
Mingsheng Ma, Wei Wang, Li Li, Xiaoyan Wang, Qiubo Huang, Chen Zhou, Yunchao Huang, Guangqiang Zhao, Lianhua Ye
Publikováno v:
Translational Oncology, Vol 46, Iss , Pp 102018- (2024)
Invasion and migration are the primary factors for mortality in lung adenocarcinoma (LUAD) patients. The precise role of RNA-binding motif protein15 (RBM15)-mediated m6A modification in LUAD is not yet fully clarified. This research aims to elucidate
Externí odkaz:
https://doaj.org/article/ac20db17b539400aa668091b804aca68