Zobrazeno 1 - 10 of 21 613 pro vyhledávání: '"n-type"'
1
Akademický článek
A structural analysis of the splice-specific functional impact of the pathogenic familial hemiplegic migraine type 1 S218L mutation on Ca v 2.1 P/Q-type channel gating.
Autor: Sack AS; Michael Smith Laboratories, University of British Columbia, 2185 East Mall, Vancouver, BC, V6T 1Z4, Canada.; Djavad Mowafaghian Centre for Brain Health, University of British Columbia, 2215 Wesbrook Mall, Vancouver, BC, V6T 1Z3, Canada., Samera GJ; Applied Genomics Centre, Kwantlen Polytechnic University, 12666 - 72 Ave, Surrey, BC, V3W 2M8, Canada., Hissen A; Applied Genomics Centre, Kwantlen Polytechnic University, 12666 - 72 Ave, Surrey, BC, V3W 2M8, Canada., Wester RJ; Applied Genomics Centre, Kwantlen Polytechnic University, 12666 - 72 Ave, Surrey, BC, V3W 2M8, Canada., Garcia E; Michael Smith Laboratories, University of British Columbia, 2185 East Mall, Vancouver, BC, V6T 1Z4, Canada.; Djavad Mowafaghian Centre for Brain Health, University of British Columbia, 2215 Wesbrook Mall, Vancouver, BC, V6T 1Z3, Canada., Adams PJ; Applied Genomics Centre, Kwantlen Polytechnic University, 12666 - 72 Ave, Surrey, BC, V3W 2M8, Canada., Snutch TP; Michael Smith Laboratories, University of British Columbia, 2185 East Mall, Vancouver, BC, V6T 1Z4, Canada. snutch@msl.ubc.ca.; Djavad Mowafaghian Centre for Brain Health, University of British Columbia, 2215 Wesbrook Mall, Vancouver, BC, V6T 1Z3, Canada. snutch@msl.ubc.ca.
Publikováno v: Molecular brain [Mol Brain] 2024 Nov 20; Vol. 17 (1), pp. 82. Date of Electronic Publication: 2024 Nov 20.
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2
Akademický článek
Peripheral Ca V 2.2 Channels in the Skin Regulate Prolonged Heat Hypersensitivity during Neuroinflammation.
Autor: Salib AN; Departments of Neuroscience, Brown University, Providence, Rhode Island 02912.; Carney Institute for Brain Science, Brown University, Providence, Rhode Island 02912., Crane MJ; Molecular Microbiology and Immunology, Brown University, Providence, Rhode Island 02912., Jamieson AM; Molecular Microbiology and Immunology, Brown University, Providence, Rhode Island 02912., Lipscombe D; Departments of Neuroscience, Brown University, Providence, Rhode Island 02912 diane_lipscombe@brown.edu.; Carney Institute for Brain Science, Brown University, Providence, Rhode Island 02912.
Publikováno v: ENeuro [eNeuro] 2024 Nov 21; Vol. 11 (11). Date of Electronic Publication: 2024 Nov 21 (Print Publication: 2024).
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3
Akademický článek
Voltage-dependent G-protein regulation of Ca V 2.2 (N-type) channels.
Autor: Nilsson M; Division of Cell and Neurobiology, Department of Biomedical and Clinical Sciences, Linköping University, SE-581 85 Linköping, Sweden., Wang K; Division of Cell and Neurobiology, Department of Biomedical and Clinical Sciences, Linköping University, SE-581 85 Linköping, Sweden., Mínguez-Viñas T; Division of Cell and Neurobiology, Department of Biomedical and Clinical Sciences, Linköping University, SE-581 85 Linköping, Sweden., Angelini M; Department of Anesthesiology and Perioperative Medicine, David Geffen School of Medicine, University of California, Los Angeles, Los Angeles, CA 90095, USA., Berglund S; Division of Cell and Neurobiology, Department of Biomedical and Clinical Sciences, Linköping University, SE-581 85 Linköping, Sweden., Olcese R; Department of Anesthesiology and Perioperative Medicine, David Geffen School of Medicine, University of California, Los Angeles, Los Angeles, CA 90095, USA.; Department of Physiology, David Geffen School of Medicine, University of California, Los Angeles, Los Angeles, CA 90095, USA., Pantazis A; Division of Cell and Neurobiology, Department of Biomedical and Clinical Sciences, Linköping University, SE-581 85 Linköping, Sweden.; Wallenberg Center for Molecular Medicine, Linköping University, SE-581 85 Linköping, Sweden.
Publikováno v: Science advances [Sci Adv] 2024 Sep 13; Vol. 10 (37), pp. eadp6665. Date of Electronic Publication: 2024 Sep 11.
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4
Akademický článek
Uncoupling the CRMP2-Ca V 2.2 Interaction Reduces Pain-Like Behavior in a Preclinical Joint-Pain Model.
Autor: Allen HN; Department of Pharmacology & Therapeutics, University of Florida College of Medicine, Gainesville, Florida., Hestehave S; Department of Molecular Pathobiology, College of Dentistry, New York University, New York, New York; Department of Experimental Medicine, University of Copenhagen, 2200 Copenhagen N, Denmark., Duran P; Department of Molecular Pathobiology, College of Dentistry, New York University, New York, New York., Nelson TS; Department of Pharmacology & Therapeutics, University of Florida College of Medicine, Gainesville, Florida., Khanna R; Department of Pharmacology & Therapeutics, University of Florida College of Medicine, Gainesville, Florida. Electronic address: r.khanna@ufl.edu.
Publikováno v: The journal of pain [J Pain] 2024 Dec; Vol. 25 (12), pp. 104664. Date of Electronic Publication: 2024 Sep 02.
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5
Akademický článek
An orally available Ca v 2.2 calcium channel inhibitor for the treatment of neuropathic pain.
Autor: Kutzsche J; Institute of Biological Information Processing 7, Structural Biochemistry, Forschungszentrum Jülich GmbH, Jülich, Germany., Guzman GA; Institute of Biological Information Processing 7, Structural Biochemistry, Forschungszentrum Jülich GmbH, Jülich, Germany., Willuweit A; Institute of Neuroscience and Medicine, Medical Imaging Physics, Forschungszentrum Jülich GmbH, Jülich, Germany., Kletke O; Institute of Neuro- und Sensory Physiology, Medical Faculty, Heinrich-Heine-Universität Düsseldorf, Düsseldorf, Germany., Wollert E; Institute of Biological Information Processing 7, Structural Biochemistry, Forschungszentrum Jülich GmbH, Jülich, Germany., Gering I; Institute of Biological Information Processing 7, Structural Biochemistry, Forschungszentrum Jülich GmbH, Jülich, Germany., Jürgens D; Institute of Biological Information Processing 7, Structural Biochemistry, Forschungszentrum Jülich GmbH, Jülich, Germany., Breitkreutz J; Institute of Pharmaceutics and Biopharmaceutics, Heinrich-Heine-Universität Düsseldorf, Düsseldorf, Germany., Stark H; Institute for Pharmaceutical and Medicinal Chemistry, Heinrich-Heine-University Düsseldorf, Düsseldorf, Germany., Beck-Sickinger AG; Institute of Biochemistry, Universität Leipzig, Leipzig, Germany., Klöcker N; Institute of Pharmaceutics and Biopharmaceutics, Heinrich-Heine-Universität Düsseldorf, Düsseldorf, Germany., Hidalgo P; Institute of Biological Information Processing 1, Molecular and Cellular Physiology, Forschungszentrum Jülich GmbH, Jülich, Germany., Willbold D; Institute of Biological Information Processing 7, Structural Biochemistry, Forschungszentrum Jülich GmbH, Jülich, Germany.; Institut für Physikalische Biologie, Heinrich-Heine-Universität Düsseldorf, Düsseldorf, Germany.
Publikováno v: British journal of pharmacology [Br J Pharmacol] 2024 Jun; Vol. 181 (12), pp. 1734-1756. Date of Electronic Publication: 2024 Feb 07.
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6
Editorial & Opinion
Structural basis for different ω-agatoxin IVA sensitivities of the P-type and Q-type Ca v 2.1 channels.
Autor: Li Z; Beijing Frontier Research Center for Biological Structures, State Key Laboratory of Membrane Biology, Tsinghua-Peking Joint Center for Life Sciences, School of Life Sciences, Tsinghua University, Beijing, China. lizhangq@tsinghua.edu.cn., Cong Y; Beijing Frontier Research Center for Biological Structures, State Key Laboratory of Membrane Biology, Tsinghua-Peking Joint Center for Life Sciences, School of Life Sciences, Tsinghua University, Beijing, China., Wu T; Beijing Frontier Research Center for Biological Structures, State Key Laboratory of Membrane Biology, Tsinghua-Peking Joint Center for Life Sciences, School of Life Sciences, Tsinghua University, Beijing, China., Wang T; Beijing Frontier Research Center for Biological Structures, State Key Laboratory of Membrane Biology, Tsinghua-Peking Joint Center for Life Sciences, School of Life Sciences, Tsinghua University, Beijing, China., Lou X; Beijing Frontier Research Center for Biological Structures, State Key Laboratory of Membrane Biology, Tsinghua-Peking Joint Center for Life Sciences, School of Life Sciences, Tsinghua University, Beijing, China., Yang X; Beijing Frontier Research Center for Biological Structures, State Key Laboratory of Membrane Biology, Tsinghua-Peking Joint Center for Life Sciences, School of Life Sciences, Tsinghua University, Beijing, China., Yan N; Beijing Frontier Research Center for Biological Structures, State Key Laboratory of Membrane Biology, Tsinghua-Peking Joint Center for Life Sciences, School of Life Sciences, Tsinghua University, Beijing, China. nyan@tsinghua.edu.cn.; Institute of Bio-Architecture and Bio-Interactions, Shenzhen Medical Academy of Research and Translation, Shenzhen, Guangdong, China. nyan@tsinghua.edu.cn.
Publikováno v: Cell research [Cell Res] 2024 Jun; Vol. 34 (6), pp. 455-457. Date of Electronic Publication: 2024 Mar 05.
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7
Akademický článek
Subcellular localization and ER-mediated cytotoxic function of α1A and α1ACT in spinocerebellar ataxia type 6.
Autor: Wang D; Department of Pathological Cell Biology, Medical Research Institute, Tokyo Medical and Dental University (TMDU), 1-5-45 Yushima, Bunkyo-ku, Tokyo, 113-8510, Japan; Department of Personalized Genomic Medicine for Health, Graduate School of Medicine, Tokyo Medical and Dental University (TMDU), 1-5-45 Yushima, Bunkyo-ku, Tokyo, 113-8510, Japan., Honda S; Department of Pathological Cell Biology, Medical Research Institute, Tokyo Medical and Dental University (TMDU), 1-5-45 Yushima, Bunkyo-ku, Tokyo, 113-8510, Japan., Shin MK; Department of Pathological Cell Biology, Medical Research Institute, Tokyo Medical and Dental University (TMDU), 1-5-45 Yushima, Bunkyo-ku, Tokyo, 113-8510, Japan., Watase K; Center for Brain Integration Research, Tokyo Medical and Dental University (TMDU), 1-5-45 Yushima, Bunkyo-ku, Tokyo, 113-8510, Japan., Mizusawa H; Center for Brain Integration Research, Tokyo Medical and Dental University (TMDU), 1-5-45 Yushima, Bunkyo-ku, Tokyo, 113-8510, Japan., Ishikawa K; Department of Personalized Genomic Medicine for Health, Graduate School of Medicine, Tokyo Medical and Dental University (TMDU), 1-5-45 Yushima, Bunkyo-ku, Tokyo, 113-8510, Japan. Electronic address: pico.nuro@tmd.ac.jp., Shimizu S; Department of Pathological Cell Biology, Medical Research Institute, Tokyo Medical and Dental University (TMDU), 1-5-45 Yushima, Bunkyo-ku, Tokyo, 113-8510, Japan. Electronic address: shimizu.pcb@mri.tmd.ac.jp.
Publikováno v: Biochemical and biophysical research communications [Biochem Biophys Res Commun] 2024 Feb 05; Vol. 695, pp. 149481. Date of Electronic Publication: 2024 Jan 05.
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8
Akademický článek
Ca V 2.1 α 1  subunit motifs that control presynaptic Ca V 2.1 subtype abundance are distinct from Ca V 2.1 preference.
Autor: Li J; Department of Anatomy and Cell Biology, University of Iowa, Iowa City, IA, USA.; Cell Developmental Biology Graduate Program, University of Iowa, Iowa City, IA, USA., Veeraraghavan P; Department of Anatomy and Cell Biology, University of Iowa, Iowa City, IA, USA., Young SM Jr; Department of Anatomy and Cell Biology, University of Iowa, Iowa City, IA, USA.; Department of Otolaryngology, Iowa Neuroscience Institute, University of Iowa, Iowa City, IA, USA.
Publikováno v: The Journal of physiology [J Physiol] 2024 Feb; Vol. 602 (3), pp. 485-506. Date of Electronic Publication: 2023 Dec 28.
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9
Akademický článek
Cracking 'the Da Vinci code' of conduct hidden in Ca v 2.1 α1 subunit for presynaptic occupation.
Autor: Fekete A; Program in Neurosciences and Mental Health, SickKids Research Institute, Toronto, Ontario, Canada.; Department of Physiology, University of Toronto, Toronto, Ontario, Canada., Wang LY; Program in Neurosciences and Mental Health, SickKids Research Institute, Toronto, Ontario, Canada.; Department of Physiology, University of Toronto, Toronto, Ontario, Canada.
Publikováno v: The Journal of physiology [J Physiol] 2024 Feb; Vol. 602 (4), pp. 539-540. Date of Electronic Publication: 2024 Feb 06.
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10
Akademický článek
Low-cost fabrication methods of ZnO nanorods and their physical and photoelectrochemical properties for optoelectronic applications.
Autor: Bakry, Mabrouk1,2 (AUTHOR), Ismail, Walid1,2 (AUTHOR), Abdelfatah, Mahmoud1,2 (AUTHOR) mahmoud.abdelfatah@sci.kfs.edu.eg, El-Shaer, Abdelhamid1,2 (AUTHOR) elshaer@sci.kfs.edu.eg
Publikováno v: Scientific Reports. 10/11/2024, Vol. 14 Issue 1, p1-15. 15p.
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