Zobrazeno 1 - 10
of 173
pro vyhledávání: '"myomiRs"'
Autor:
Marta Seco-Cervera, José Santiago Ibáñez-Cabellos, Federico V. Pallardo, José-Luis García-Giménez, Anna Aulinas, Luciana Martel-Duguech, Susan M. Webb, Elena Valassi
Publikováno v:
Frontiers in Endocrinology, Vol 15 (2024)
IntroductionPatients with Cushing’s syndrome (CS) in remission show sustained fatigue, myopathy, and an increased prevalence of sarcopenia. The mechanisms that determine these persistent muscle problems are not well known. We aimed to identify circ
Externí odkaz:
https://doaj.org/article/5ece26e418bd4941ab70e0229556a348
Publikováno v:
BMC Geriatrics, Vol 21, Iss 1, Pp 1-11 (2021)
Abstract Background Interorgan communication networks established during exercise in several different tissues can be mediated by several exercise-induced factors. Therefore, the present study aimed to investigate the effects of resistance-type train
Externí odkaz:
https://doaj.org/article/a0f06c956f30455f9247646860a4eea4
Publikováno v:
Frontiers in Neurology, Vol 13 (2022)
Creatine kinase (CK) as a biomarker has long been expected to be replaced by other fluid biomarkers for Duchenne muscular dystrophy (DMD) because it is independent of disease severity. Growing evidence has demonstrated that muscle-specific microRNAs,
Externí odkaz:
https://doaj.org/article/556012b501ac4d0da4521e3b40cb813b
Autor:
Chrystalla Mytidou, Andrie Koutsoulidou, Margarita Zachariou, Marianna Prokopi, Konstantinos Kapnisis, George M. Spyrou, Andreas Anayiotos, Leonidas A. Phylactou
Publikováno v:
Frontiers in Physiology, Vol 12 (2021)
Skeletal muscle growth and maintenance depend on two tightly regulated processes, myogenesis and muscle regeneration. Both processes involve a series of crucial regulatory molecules including muscle-specific microRNAs, known as myomiRs. We recently s
Externí odkaz:
https://doaj.org/article/86f3128605ab452590a0feba08a9e1c5
Autor:
Urszula Głowniak-Kwitek, Asier Laria Caballero, Iwona Bronisz-Budzyńska, Magdalena Kozakowska, Kalina Andrysiak, Jacek Stępniewski, Agnieszka Łoboda, Józef Dulak
Publikováno v:
Pharmacological Reports. 75:397-410
Background Impaired muscle regeneration is a hallmark of Duchenne muscular dystrophy (DMD), a neuromuscular disorder caused by mutations in the DMD gene encoding dystrophin. The lack of heme oxygenase-1 (HO-1, Hmox1), a known anti-inflammatory and cy
Autor:
Jiapeng Zhang, Qi Meng, Jingzi Zhong, Min Zhang, Xiao Qin, Xiaohua Ni, Jiawen Ma, Yangwen He, Dan Zeng, Dan Lan
Publikováno v:
Frontiers in Neurology, Vol 11 (2020)
Externí odkaz:
https://doaj.org/article/9930df550e5e4b1cac22657ada11cb1b
Autor:
Jiapeng Zhang, Qi Meng, Jingzi Zhong, Min Zhang, Xiao Qin, Xiaohua Ni, Jiawen Ma, Yangwen He, Dan Zeng, Dan Lan
Publikováno v:
Frontiers in Neurology, Vol 11 (2020)
Background: Duchenne/Becker muscular dystrophy (DMD/BMD) is an X-linked recessive lethal neuromuscular disease. MicroRNAs expressed in striated muscle, myomiRs, have been proposed as its potential biomarkers. Serum creatine kinase (CK) is commonly us
Externí odkaz:
https://doaj.org/article/86e194ad0cc443469cafd0c739db3d1f
Publikováno v:
European Journal of Translational Myology (2020)
Multiple acyl-CoA dehydrogenase deficiency (MADD) is a rare fatty acids oxidation disorder which is often associated with deficiency of electron transfer flavoprotein dehydrogenase (ETFDH). In this study we reported clinical features and evaluation o
Externí odkaz:
https://doaj.org/article/3ef02ca74d004f5b81e5b130be8ae1a3
Autor:
Ying Si, Xianqin Cui, David K. Crossman, Jiaying Hao, Mohamed Kazamel, Yuri Kwon, Peter H. King
Publikováno v:
Neurobiology of Disease, Vol 114, Iss , Pp 85-94 (2018)
ALS is a fatal neurodegenerative disorder of motor neurons leading to progressive atrophy and weakness of muscles. Some of the earliest pathophysiological changes occur at the level of skeletal muscle and the neuromuscular junction. We previously ide
Externí odkaz:
https://doaj.org/article/2d9018d9ab03460daa8f22edd630b1f4
Circulating myomiRs: a new class of biomarkers to monitor skeletal muscle in physiology and medicine
Publikováno v:
Journal of Cachexia, Sarcopenia and Muscle, Vol 9, Iss 1, Pp 20-27 (2018)
Abstract MicroRNAs (miRNA) are small non‐coding RNAs that target mRNAs and are consequently involved in the post‐transcriptional regulation of gene expression. Some miRNAs are ubiquitously expressed in tissue, while others are tissue‐specific o
Externí odkaz:
https://doaj.org/article/988d02882e3342a38f290ad439c7235a