Zobrazeno 1 - 10
of 147
pro vyhledávání: '"myeloproliferative neoplasms(mpn)"'
Autor:
Christopher Puli'uvea, Tracey Immanuel, Taryn N. Green, Peter Tsai, Peter R. Shepherd, Maggie L. Kalev-Zylinska
Publikováno v:
Hematology, Vol 29, Iss 1 (2024)
ABSTRACTObjectives: This study aimed to compile bioinformatic and experimental information for JAK2 missense variants previously reported in myeloproliferative neoplasms (MPN) and determine if germline JAK2-I724T, recently found to be common in New Z
Externí odkaz:
https://doaj.org/article/ce5b4c33076141b4ba8b6008985068fb
Publikováno v:
Frontiers in Hematology, Vol 3 (2024)
Although the involvement of glycan structures in diseases has long been recognized, their detailed and high-throughput investigation has only recently been made possible due to technological advancements. For this reason, glycosylation is a generally
Externí odkaz:
https://doaj.org/article/f89846b58b844d87a675276b1b42b307
Autor:
Tobias Idor Boklund, Jordan Snyder, Johanne Gudmand-Hoeyer, Morten Kranker Larsen, Trine Alma Knudsen, Christina Schjellerup Eickhardt-Dalbøge, Vibe Skov, Lasse Kjær, Hans C. Hasselbalch, Morten Andersen, Johnny T. Ottesen, Thomas Stiehl
Publikováno v:
Frontiers in Immunology, Vol 15 (2024)
IntroductionThe Philadelphia chromosome-negative myeloproliferative neoplasms are a group of slowly progressing haematological malignancies primarily characterised by an overproduction of myeloid blood cells. Patients are treated with various drugs,
Externí odkaz:
https://doaj.org/article/d2e7c2148e984299bb4c140c1200e5d0
Autor:
Kathrin Olschok, Bianca Altenburg, Marcelo A. S. de Toledo, Angela Maurer, Anne Abels, Fabian Beier, Deniz Gezer, Susanne Isfort, Katrin Paeschke, Tim H. Brümmendorf, Martin Zenke, Nicolas Chatain, Steffen Koschmieder
Publikováno v:
Frontiers in Oncology, Vol 13 (2023)
Imetelstat shows activity in patients with myeloproliferative neoplasms, including primary myelofibrosis (PMF) and essential thrombocythemia. Here, we describe a case of prolonged disease stabilization by imetelstat treatment of a high-risk PMF patie
Externí odkaz:
https://doaj.org/article/22f86771bc0443b6890a712facd8c199
Autor:
Yi-zhi Jiang, Zhong-ling Wei, Na-na Wang, Chen Huang, Jun Huang, Jia-wei Yan, Ran Wang, Zheng-zhi Yu, Dong-ping Huang
Publikováno v:
Hematology, Vol 27, Iss 1, Pp 1290-1293 (2022)
ABSTRACTBackground: The V617F mutation of Janus-associated kinase 2 (JAK2) is common in myeloproliferative neoplasms (MPN). JAK2 V617F mutation can be detected in patients with de novo acute myeloid leukemia (AML), but de novo acute promyelocytic leu
Externí odkaz:
https://doaj.org/article/12506528c7a7407c9814715c7a58a296
Autor:
Sylvie Hermouet
Publikováno v:
Frontiers in Oncology, Vol 13 (2023)
Knowledge on the myeloproliferative neoplasms (MPNs) – polycythemia vera (PV), essential thrombocythemia (ET), primary myelofibrosis (PMF) – has accumulated since the discovery of the JAK/STAT-activating mutations associated with MPNs: JAK2V617F,
Externí odkaz:
https://doaj.org/article/76af1ef215d24761beb89586dcfafecd
Autor:
Sabine Felser, Julia Rogahn, Philipp le Coutre, Haifa Kathrin Al-Ali, Susann Schulze, Lars-Olof Muegge, Julia Gruen, Jan Geissler, Veronika Kraze-Kliebhahn, Christian Junghanss
Publikováno v:
Frontiers in Oncology, Vol 12 (2023)
BackgroundPhysical activity (PA) is a non-pharmacological approach to alleviate symptom burden and improve health-related quality of life (HrQoL) in cancer patients (pts). Whether pts with myeloproliferative neoplasms (MPN) PA behavior changes due to
Externí odkaz:
https://doaj.org/article/0bbcbf83eaeb438eb57668f6a2729ccd
Autor:
Takashi Shimoyama, Hiroki Yamaguchi, Kazumi Kimura, Fumiaki Suzuki, Toshiyuki Hayashi, Satoshi Wakita
Publikováno v:
Frontiers in Neurology, Vol 13 (2022)
BackgroundHeadache is frequently reported as a neurological manifestation of myeloproliferative neoplasms (MPNs), including polycythemia vera and essential thrombocythaemia. This study sought to clarify the clinical characteristics and response to tr
Externí odkaz:
https://doaj.org/article/405dd9cbfc2444cb9344617f036ec9d6
Akademický článek
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Autor:
Steffen Koschmieder
Publikováno v:
Hemato, Vol 2, Iss 3, Pp 392-402 (2021)
Patients with myeloproliferative neoplasm (MPN) are potentially facing diminished life expectancy and decreased quality of life, due to thromboembolic and hemorrhagic complications, progression to myelofibrosis or acute leukemia with ensuing signs of
Externí odkaz:
https://doaj.org/article/75a5c183689146ddbacb843613fd0ba5