Zobrazeno 1 - 10
of 355
pro vyhledávání: '"myeloid malignancy"'
Autor:
Eitan Halper-Stromberg, Victoria Stinnett, Laura Morsberger, Aparna Pallavajjala, Mark J. Levis, Amy E. DeZern, Michelle Lei, Brian Phan, Rena R. Xian, Christopher D. Gocke, Guilin Tang, Ying S. Zou
Publikováno v:
Experimental Hematology & Oncology, Vol 13, Iss 1, Pp 1-5 (2024)
Abstract 1q jumping translocation (JT) is rare and its molecular profiles in myeloid malignancies are not well-known. This study evaluated gene mutations in 1q-JT cohorts (0.38%) from hematological malignant specimens that underwent genetic analysis
Externí odkaz:
https://doaj.org/article/77a46d40981d4860855f1a65cee2f637
Autor:
Yaxin Wang, Qingyun Wang, Hanyun Ren, Yujun Dong, Qingya Wang, Zeyin Liang, Yue Yin, Wei Liu, Weilin Xu, Na Han, Yuan Li
Publikováno v:
Frontiers in Oncology, Vol 14 (2024)
IntroductionAcute myeloid leukemia (AML) and myelodysplastic syndrome (MDS) constitute myeloid malignancies, and allogeneic hematopoietic stem cell transplantation (allo-HSCT) is considered as a potentially optimal approach for achieving a long term
Externí odkaz:
https://doaj.org/article/d0334448497b4098b688a1b56b519cb1
Publikováno v:
Cell Communication and Signaling, Vol 20, Iss 1, Pp 1-16 (2022)
Abstract Langerhans cell histiocytosis (LCH) is an inflammatory myeloid malignancy in the “L-group” histiocytosis. Mitogen-activated protein kinase (MAPK) pathway activating mutations are detectable in nearly all LCH lesions. However, the pathoge
Externí odkaz:
https://doaj.org/article/d759bc25800e4ddda8a73ad15c73084b
Autor:
Razan Mohty, Rama Al Hamed, Ali Bazarbachi, Eolia Brissot, Arnon Nagler, Amer Zeidan, Mohamad Mohty
Publikováno v:
Journal of Hematology & Oncology, Vol 15, Iss 1, Pp 1-16 (2022)
Abstract Myelodysplastic syndromes (MDS) are a heterogeneous clonal disease of myeloid neoplasms characterized by ineffective hematopoiesis, variable degree of cytopenias, and an increased risk of progression to acute myeloid leukemia (AML). Molecula
Externí odkaz:
https://doaj.org/article/12dfeeb36de342abb9dc383635ac2ca2
Autor:
Zhangjie Chen, Sisi Zhen, Tingting Zhang, Yuyan Shen, Aiming Pang, Donglin Yang, Rongli Zhang, Qiaoling Ma, Yi He, Jialin Wei, Weihua Zhai, Xin Chen, Erlie Jiang, Mingzhe Han, Sizhou Feng
Publikováno v:
Frontiers in Oncology, Vol 13 (2023)
IntroductionSince allogeneic stem cell transplantation (allo-HSCT) is considered one of the curative treatments for acute myeloid leukemia (AML) and myelodysplastic syndrome (MDS), hematological relapse following allo-HSCT remained a crucial concern
Externí odkaz:
https://doaj.org/article/a0c7923f19364a1eb45b45749b7623da
Akademický článek
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Publikováno v:
Clinical Pediatric Hematology-Oncology, Vol 28, Iss 2, Pp 89-92 (2021)
One of the pathophysiologic mechanism of inherited thrombocytopenia is a defect in transcription factors that regulate the expression of multiple genes required for megakaryopoiesis. Runt-related transcription factor 1 (RUNX1) binds to its heterodime
Externí odkaz:
https://doaj.org/article/8279ffaf7b2c46fa9a9240759f819c1f
Autor:
Gaël Vermeersch, Michel Delforge, Violaine Havelange, Carlos Graux, Lucienne Michaux, Timothy Devos
Publikováno v:
Frontiers in Oncology, Vol 12 (2022)
Chronic neutrophilic leukemia (CNL) is a rare but potentially aggressive BCR::ABL1 negative myeloproliferative neoplasm, characterized by sustained mature, neutrophilic leukocytosis. The discovery of key driver mutations in the colony-stimulating-fac
Externí odkaz:
https://doaj.org/article/d3765df5ae2e42bca200a275aabdafcf
Publikováno v:
Open Biology, Vol 12, Iss 10 (2022)
HOXA9 and MEIS1 are co-expressed in over 50% of acute myeloid leukaemia (AML) and play essential roles in leukaemogenesis, but the mechanisms involved are poorly understood. Diverse animal models offer valuable tools to recapitulate different aspects
Externí odkaz:
https://doaj.org/article/b5ffad1aafd5436e908d25c96a8f3e35
Akademický článek
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