Zobrazeno 1 - 10
of 517
pro vyhledávání: '"myeloid‐derived suppressor cells (MDSCs)"'
Publikováno v:
Shanghai Jiaotong Daxue xuebao. Yixue ban, Vol 44, Iss 8, Pp 1011-1022 (2024)
Objective·To explore the regulatory mechanism of folate cycle metabolism in the immunosuppressive effect of myeloid derived suppressor cells (MDSCs).Methods·Bone marrow cells were isolated from C57BL/6 mice and cultured in RPMI 1640 medium suppleme
Externí odkaz:
https://doaj.org/article/2e308de0f5314719b6b598675528efba
Autor:
Xiaoqiang Wang, Shoubao Ma, Przemyslaw Twardowski, Clayton Lau, Yin S. Chan, Kelly Wong, Sai Xiao, Jinhui Wang, Xiwei Wu, Paul Frankel, Timothy G. Wilson, Timothy W Synold, Cary Presant, Tanya Dorff, Jianhua Yu, David Sadava, Shiuan Chen
Publikováno v:
Clinical and Translational Medicine, Vol 14, Iss 10, Pp n/a-n/a (2024)
Abstract Background In a previously reported Phase I trial, we observed therapy‐associated declines in circulating myeloid‐derived suppressor cells (MDSCs) with the administration of white button mushroom (WBM) tablets in prostate cancer (PCa) pa
Externí odkaz:
https://doaj.org/article/77ac3f0171a649cc910c82256ea2576a
Autor:
Eun-Young Shin, Suji Jeong, Jeoung Eun Lee, Dong Seok Jeong, Dong Keun Han, Seok-Ho Hong, Dong Ryul Lee
Publikováno v:
Stem Cell Research & Therapy, Vol 15, Iss 1, Pp 1-13 (2024)
Abstract Objectives Currently, no approved stem cell-based therapies for preserving ovarian function during aging. To solve this problem, we developed a long-term treatment for human embryonic stem cell-derived mesenchymal progenitor cells (hESC-MPCs
Externí odkaz:
https://doaj.org/article/5d9de890cdc7471d9a21026a76c86cee
Autor:
José L. Solórzano, Victoria Menéndez, Edwin Parra, Luisa Solis, Ruth Salazar, Mónica García-Cosío, Fina Climent, Sara Fernández, Eva Díaz, Alejandro Francisco-Cruz, Joseph Khoury, Mei Jiang, Auriole Tamegnon, Carlos Montalbán, Ignacio Melero, Ignacio Wistuba, Carlos De Andrea, Juan F. García
Publikováno v:
OncoImmunology, Vol 13, Iss 1 (2024)
The Hodgkin and Reed – Sternberg (HRS) cells in classical Hodgkin Lymphoma (cHL) actively modify the immune tumor microenvironment (TME) attracting immunosuppressive cells and expressing inhibitory molecules. A high frequency of myeloid cells in th
Externí odkaz:
https://doaj.org/article/eca23b7e29a44b36a41152a418b1a45b
Autor:
Beibei Guo, Yawen Zheng, Yujia Fan, Yang Yang, Yuxing Wang, Liping Qin, Yachun An, Xiaoran Xu, Xiyu Zhang, Gongping Sun, Hao Dou, Changshun Shao, Yaoqin Gong, Baichun Jiang, Huili Hu
Publikováno v:
Neoplasia: An International Journal for Oncology Research, Vol 53, Iss , Pp 101005- (2024)
Colorectal cancer (CRC) stands as a prevalent malignancy globally. A pivotal event in CRC pathogenesis involves the loss-of-function mutation in the APC gene, leading to the formation of benign polyps. Despite the well-established role of APC, the co
Externí odkaz:
https://doaj.org/article/4fd74afd22c64f028c84d6f647d32cae
Autor:
Fernando García-Arévalo, Ana Gabriela Leija-Montoya, Javier González-Ramírez, Mario Isiordia-Espinoza, Idanya Serafín-Higuera, Dulce Martha Fuchen-Ramos, J. Gustavo Vazquez-Jimenez, Nicolas Serafín-Higuera
Publikováno v:
Frontiers in Immunology, Vol 15 (2024)
The oral cavity presents a diverse microbiota in a dynamic balance with the host. Disruption of the microbial community can promote dysregulation of local immune response which could generate oral diseases. Additionally, alterations in host immune sy
Externí odkaz:
https://doaj.org/article/64433e614c654fdeb5c5eb6571f80fce
Publikováno v:
Cancer Medicine, Vol 12, Iss 15, Pp 16370-16385 (2023)
Abstract Background Preclinical studies and clinical trials have demonstrated that tumor‐intrinsic activation of the cell cycle program impedes anticancer immunotherapy. Identification of cell cycle‐related biomarkers may provide novel therapeuti
Externí odkaz:
https://doaj.org/article/1a8ba3f6252848bdb256d737c0dddcc0
Publikováno v:
Cancer Medicine, Vol 13, Iss 4, Pp n/a-n/a (2024)
Abstract Background In this study, we investigated infection‐related tumor growth, focusing on myeloid‐derived suppressor cells (MDSCs) in clinical and experimental settings. Patients and Methods In the clinical study, a total 109 patients who un
Externí odkaz:
https://doaj.org/article/1d8f22f8019649d0a3ae857be54a82ce
Autor:
Tao Wu, Xuan Zhang, Xinxing Liu, Xinyi Cai, Tao Shen, Dingguo Pan, Rui Liang, Rong Ding, Ruixi Hu, Jianhua Dong, Furong Li, Jinsha Li, Lin Xie, Chunlong Wang, Shilei Geng, Zhaoyu Yang, Lu Xing, YunFeng Li
Publikováno v:
BMC Medicine, Vol 21, Iss 1, Pp 1-18 (2023)
Abstract Background The objective response rate of microsatellite instability-high (MSI-H) metastatic colorectal cancer (mCRC) patients with first-line anti-programmed cell death protein-1 (PD-1) monotherapy is only 40–45%. Single-cell RNA sequenci
Externí odkaz:
https://doaj.org/article/c3c7dbc4eeda41bebaf38d641b01f71c
Autor:
Lorenza Tamberi, Alessia Belloni, Armanda Pugnaloni, Maria Rita Rippo, Fabiola Olivieri, Antonio Domenico Procopio, Giuseppe Bronte
Publikováno v:
Cells, Vol 13, Iss 7, p 643 (2024)
The neuro-immune axis has a crucial function both during physiological and pathological conditions. Among the immune cells, myeloid-derived suppressor cells (MDSCs) exert a pivotal role in regulating the immune response in many pathological condition
Externí odkaz:
https://doaj.org/article/0e5b80d773524bda9788c8aee3092408