Zobrazeno 1 - 10
of 60
pro vyhledávání: '"myelofibrosis (MF)"'
Autor:
Brian D. Ross, Dariya Malyarenko, Kevin Heist, Ghoncheh Amouzandeh, Youngsoon Jang, Christopher A. Bonham, Cyrus Amirfazli, Gary D. Luker, Thomas L. Chenevert
Publikováno v:
Tomography, Vol 9, Iss 2, Pp 552-566 (2023)
Quantitative MRI biomarkers are sought to replace painful and invasive sequential bone-marrow biopsies routinely used for myelofibrosis (MF) cancer monitoring and treatment assessment. Repeatability of MRI-based quantitative imaging biomarker (QIB) m
Externí odkaz:
https://doaj.org/article/93b2a7441b1e479ba42047b92d7cf3f2
Autor:
Kathrin Olschok, Bianca Altenburg, Marcelo A. S. de Toledo, Angela Maurer, Anne Abels, Fabian Beier, Deniz Gezer, Susanne Isfort, Katrin Paeschke, Tim H. Brümmendorf, Martin Zenke, Nicolas Chatain, Steffen Koschmieder
Publikováno v:
Frontiers in Oncology, Vol 13 (2023)
Imetelstat shows activity in patients with myeloproliferative neoplasms, including primary myelofibrosis (PMF) and essential thrombocythemia. Here, we describe a case of prolonged disease stabilization by imetelstat treatment of a high-risk PMF patie
Externí odkaz:
https://doaj.org/article/22f86771bc0443b6890a712facd8c199
Autor:
Dragomira Nikolova, Atanas Radinov
Publikováno v:
Folia Medica, Vol 64, Iss 4, Pp 655-660 (2022)
Introduction: Myelofibrosis (MF) belongs to a group of conditions known as Philadelphia-negative myeloproliferative neoplasms (MPN). Bleeding or various vascular complications could be the main causes of morbidity and mortality in patients with MF. M
Externí odkaz:
https://doaj.org/article/1ab3b70d4eaf4de4ac00f4e7937e9246
Akademický článek
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Autor:
Giuseppe A. Palumbo, Sara Galimberti, Wilma Barcellini, Daniela Cilloni, Nicola Di Renzo, Elena Maria Elli, Carlo Finelli, Luca Maurillo, Alessandra Ricco, Pellegrino Musto, Rodolfo Russo, Roberto Latagliata
Publikováno v:
Frontiers in Oncology, Vol 11 (2021)
Iron chelation therapy (ICT) has become a mainstay in heavily transfused hematological patients, with the aim to reduce iron overload (IOL) and prevent organ damage. This therapeutic approach is already widely used in thalassemic patients and in low-
Externí odkaz:
https://doaj.org/article/52bbfeff9ecf45758d4abb575c96e281
Publikováno v:
European Medical Journal Hematology, Vol 7, Iss 1, Pp 69-79 (2019)
Immune thrombocytopenic purpura is a clinical syndrome of thrombocytopenia that manifests as a bleeding tendency, typical skin rashes, easy bruising, or extravasation of blood from the capillaries. Defects in the thrombopoietin-receptor (TPOR)/myelop
Externí odkaz:
https://doaj.org/article/5d538f4e9e5041be99257de2374427f1
Publikováno v:
Balkan Journal of Medical Genetics, Vol 22, Iss 1, Pp 57-60 (2019)
Myelofibrosis (MF) is characterized by a presence of an extra fibrous tissue in the bone marrow and additional hematopoiesis. The somatic mutation in the Janus kinase 2 (JAK2) gene (V617F) occurs gradually and is detected in about 50.0% of myelofibro
Externí odkaz:
https://doaj.org/article/14dbd66e31384fd2ac81affcdcc2e55a
Akademický článek
Tento výsledek nelze pro nepřihlášené uživatele zobrazit.
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Autor:
Jan Jacques Michiels, Hendrik De Raeve, Francisca Valster, Vincent Potters, Yonggoo Kim, Myungshin Kim
Publikováno v:
European Medical Journal, Vol 2, Iss 2, Pp 72-81 (2017)
Improved Clinical, Laboratory, Molecular, and Pathological (CLMP) 2017 criteria for myeloproliferative neoplasms (MPN) define the JAK2V617F trilinear MPNs as a broad continuum of essential thrombocythaemia (ET), polycythaemia vera (PV), masked PV, an
Externí odkaz:
https://doaj.org/article/5e22444b17c845d3bee2e3d9dbc630a4
Autor:
Giuseppe A. Palumbo, Stefania Stella, Maria Stella Pennisi, Cristina Pirosa, Elisa Fermo, Sonia Fabris, Daniele Cattaneo, Alessandra Iurlo
Publikováno v:
Frontiers in Oncology, Vol 9 (2019)
The hallmark of BCR-ABL1-negative myeloproliferative neoplasms (MPNs) is the presence of a driver mutation in JAK2, CALR, or MPL gene. These genetic alterations represent a key feature, useful for diagnostic, prognostic and therapeutical approaches.
Externí odkaz:
https://doaj.org/article/2b7c577213dd4d8dbd6fd4e543daff1f