Zobrazeno 1 - 10
of 39
pro vyhledávání: '"myší model"'
Autor:
Syding, Linn Amanda
Angelman syndrome (AS) is a neurodevelopmental disease found in 1 to 10,000 to 40,000 births, exhibiting an equal gender ratio. Key characteristics of the disease include an ataxic gait with tremor, severe mental retardation, profound speech impairme
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=od______2186::e233cb9881867a23e555d212487c1218
http://www.nusl.cz/ntk/nusl-520640
http://www.nusl.cz/ntk/nusl-520640
Autor:
Holečková, Markéta
Diamond-Blackfan anemia (DBA) is a rare congenital bone marrow failure syndrome characterized by deficient development of erythroid progenitors and accompanied by a variable set of developmental defects. About 25 % of patients have mutations of the s
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=od______2186::4c6c819420ed250e8c7f388641e1384e
http://www.nusl.cz/ntk/nusl-509047
http://www.nusl.cz/ntk/nusl-509047
Autor:
Aulichová, Veronika
Lipid nanoparticles are the most advanced non-viral delivery system of nucleic acids. They enable safe and efficient transport of nucleic acids to the targeted cells and represent a key enabling technology of RNA therapeutics. RNA therapeutics repres
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=od______2186::2774971f315fbe484d865e12e88e6fe6
http://www.nusl.cz/ntk/nusl-509617
http://www.nusl.cz/ntk/nusl-509617
Autor:
Merc, Veronika
Identification of transcription factors involved in a complex network regulating the development of neurosensory cells in the inner ear is a key point for understanding the pathophysiology of hearing loss, development of new therapeutic tools, and fo
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=od______2186::e542f766ada5482d57a6753fb4d66855
http://www.nusl.cz/ntk/nusl-505738
http://www.nusl.cz/ntk/nusl-505738
Autor:
Hybešová, Michaela
Stem cell differentiation is controlled by coordinated regulation of gene transcription. One of the regulatory factors is the loosening of chromatin and the accessibility of DNA to transcription factors. Chromatin remodeling is mediated by remodeling
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=od______2186::e3fae15e0b764c9cc6eef92b5fece379
http://www.nusl.cz/ntk/nusl-509195
http://www.nusl.cz/ntk/nusl-509195
Autor:
Nováková, Rozálie
Autism Spectrum Disorder (ASD) is a neurodevelopmental disorder characterised by repetitive behaviour and impairments in social behaviour and social communication. The whole aetiological heterogeneity is still not fully elucidated. It is then very im
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=od______2186::72cf8303b9edb2c33eeceb5f9406d043
http://www.nusl.cz/ntk/nusl-510327
http://www.nusl.cz/ntk/nusl-510327
Autor:
Eliáš, Jan
Kallikrein-related peptidases (KLKs) are a subgroup of serine proteases of undisputable importance for a variety of functions, whose dysregulation has been linked to several pathological phenotypes. Among those pathologies, the Netherton syndrome sta
Externí odkaz:
http://www.nusl.cz/ntk/nusl-451743
Autor:
Malfatti, Jessica
1 Abstract Diabetes mellitus is characterized by the dysfunction and reduction of insulin-producing cells, resulting in hyperglycemia, which in long term harms the organism. For future therapy, it is crucial to understand the function of various fact
Externí odkaz:
http://www.nusl.cz/ntk/nusl-452374
Autor:
Stehlíková, Zuzana
Psoriasis is a chronic, immune-mediated inflammatory skin disease. Its pathogenesis is associated with dysregulated cooperation among keratinocytes, innate and adaptive immune cells, coupled with environmental triggers, including microbiota. The aim
Externí odkaz:
http://www.nusl.cz/ntk/nusl-438795
Autor:
Matějková, Kateřina
To improve modern therapeutic and diagnostic methods, it is crucial to understand the development of the cardiac sympathetic system and to identify the genes involved in its regulation. Neural crest cells give rise to the sympathetic precursors that
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=od______2186::c40b6aff74f1ead54674531abe84aceb
http://www.nusl.cz/ntk/nusl-446457
http://www.nusl.cz/ntk/nusl-446457