Zobrazeno 1 - 10
of 69
pro vyhledávání: '"muscle contraction and relaxation"'
Autor:
Thomas E. Jensen, Erik A. Richter, Nicoline R. Andersen, Ida L. Nielsen, Lykke Sylow, Lisbeth L. V. Møller, Jonas R. Knudsen
Publikováno v:
Møller, L L V, Nielsen, I L, Knudsen, J R, Andersen, N R, Jensen, T E, Sylow, L & Richter, E A 2020, ' The p21-activated kinase 2 (PAK2), but not PAK1, regulates contraction-stimulated skeletal muscle glucose transport ', Physiological Reports, vol. 8, no. 12, e14460 . https://doi.org/10.14814/phy2.14460
Physiological Reports, Vol 8, Iss 12, Pp n/a-n/a (2020)
Physiological Reports
Physiological Reports, Vol 8, Iss 12, Pp n/a-n/a (2020)
Physiological Reports
Aim Muscle contraction stimulates skeletal muscle glucose transport. Since it occurs independently of insulin, it is an important alternative pathway to increase glucose transport in insulin‐resistant states, but the intracellular signaling mechani
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::259c594eb80aae9df17c8333f7f5355f
https://curis.ku.dk/ws/files/251694542/M_ller_et_al_Physiological_Reports_2020_Vol_8_12_e14460.pdf
https://curis.ku.dk/ws/files/251694542/M_ller_et_al_Physiological_Reports_2020_Vol_8_12_e14460.pdf
Publikováno v:
Physiological Reports, Vol 7, Iss 17, Pp n/a-n/a (2019)
Physiological Reports
Physiological Reports
Airway diseases such as asthma are triggered by inflammation and mediated by proinflammatory cytokines such as tumor necrosis factor alpha (TNFα). Our goal was to systematically examine the potential mechanisms underlying the effect of TNFα on airw
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d22cd6bcb1234dc2cc39c157a730fcd8
https://doaj.org/article/49ad9e7f20fe45f2989f7e4baa39b147
https://doaj.org/article/49ad9e7f20fe45f2989f7e4baa39b147
Publikováno v:
Physiological Reports
Physiological Reports, Vol 7, Iss 16, Pp n/a-n/a (2019)
Physiological Reports, Vol 7, Iss 16, Pp n/a-n/a (2019)
The sarco/endoplasmic reticulum Ca2+‐ATPase (SERCA) is imperative for normal cardiac function regulating both muscle relaxation and contractility. SERCA2a is the predominant isoform in cardiac muscles and is inhibited by phospholamban (PLN). Under
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::985353db1cae5db66a9e3747557481f8
https://pubmed.ncbi.nlm.nih.gov/31444868
https://pubmed.ncbi.nlm.nih.gov/31444868
Autor:
Thomas Graven-Nielsen, Jens Myrup Thomsen, Rogerio Pessoto Hirata, Ryan Godsk Larsen, Jens Brøndum Frøkjær, Eva R. Poulsen, Rudi Steffensen
Publikováno v:
Physiological Reports
Larsen, R G, Thomsen, J M, Hirata, R P, Steffensen, R, Poulsen, E R, Frøkjær, J B & Graven-Nielsen, T 2019, ' Impaired microvascular reactivity after eccentric muscle contractions is not restored by acute ingestion of antioxidants or dietary nitrate ', Physiological Reports, vol. 7, no. 13, e14162 . https://doi.org/10.14814/phy2.14162
Physiological Reports, Vol 7, Iss 13, Pp n/a-n/a (2019)
Larsen, R G, Thomsen, J M, Hirata, R P, Steffensen, R, Poulsen, E R, Frøkjær, J B & Graven-Nielsen, T 2019, ' Impaired microvascular reactivity after eccentric muscle contractions is not restored by acute ingestion of antioxidants or dietary nitrate ', Physiological Reports, vol. 7, no. 13, e14162 . https://doi.org/10.14814/phy2.14162
Physiological Reports, Vol 7, Iss 13, Pp n/a-n/a (2019)
Unaccustomed eccentric exercise leads to impaired microvascular function but the underlying mechanism is unknown. In this study, we evaluated the role of oxidative stress and of nitric oxide (NO) bioavailability. Thirty young men and women performed
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c332082f6d67bd19b291b846fc05c647
http://europepmc.org/articles/PMC6640596
http://europepmc.org/articles/PMC6640596
Autor:
Pieter P. de Tombe, Tepmanas Bupha-Intr, Munthana Wadthaisong, Jonggonnee Wattanapermpool, Namthip Witayavanitkul
Publikováno v:
Physiological Reports
Physiological Reports, Vol 7, Iss 14, Pp n/a-n/a (2019)
Physiological Reports, Vol 7, Iss 14, Pp n/a-n/a (2019)
Androgen therapy provides cardiovascular benefits for hypogonadism. However, myocardial hypertrophy, fibrosis, and infarction have been reported in testosterone or androgenic anabolic steroid abuse. Therefore, better understanding of the factors lead
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3e0e9b1248cd3a8a4699c4977f2b7a6e
http://europepmc.org/articles/PMC6661270
http://europepmc.org/articles/PMC6661270
Publikováno v:
Physiological Reports, Vol 7, Iss 8, Pp n/a-n/a (2019)
Møller, A L, Hjortdal, V E, Bødtkjer, D B & Boedtkjer, E 2019, ' Acidosis inhibits rhythmic contractions of human thoracic ducts ', Physiological Reports, vol. 7, no. 8, e14074 . https://doi.org/10.14814/phy2.14074
Physiological Reports
Møller, A L, Hjortdal, V E, Bødtkjer, D B & Boedtkjer, E 2019, ' Acidosis inhibits rhythmic contractions of human thoracic ducts ', Physiological Reports, vol. 7, no. 8, e14074 . https://doi.org/10.14814/phy2.14074
Physiological Reports
Lymph vessels counteract edema by transporting interstitial fluid from peripheral tissues to the large veins and serve as conduits for immune cells, cancer cells, and pathogens. Because edema during inflammation and malignancies is frequently associa
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::156bbfdc7936846a9e92502487cd6e6b
https://doaj.org/article/3f42d538b2614784a20397d23ea034ea
https://doaj.org/article/3f42d538b2614784a20397d23ea034ea
Publikováno v:
The Journal of Physiology
Key points Regulatory light chain (RLC) phosphorylation has been shown to alter the ability of muscle to produce force and power during shortening and to alter the rate of force redevelopment (k tr) at submaximal [Ca2+].Increasing RLC phosphorylation
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::3906cbd8456d452abd303b2e596fd471
http://europepmc.org/articles/PMC5023691
http://europepmc.org/articles/PMC5023691
Autor:
David J. Durgan, Julia O. Reynolds, Robert M. Bryan, Harry Karmouty-Quintana, Lavannya M. Pandit, George G. Rodney, Melanie G. Kitagawa
Publikováno v:
Physiological Reports
We have previously shown Twik‐2−/− mice develop pulmonary hypertension and vascular remodeling. We hypothesized that distal pulmonary arteries (D‐PAs) of the Twik‐2−/− mice are hypercontractile under physiological venous conditions due
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7e7d4c16a6110aed2b68bf0055930a6e
http://europepmc.org/articles/PMC6328926
http://europepmc.org/articles/PMC6328926
Publikováno v:
Physiological Reports
Intrauterine growth restriction (IUGR) is known to alter vascular smooth muscle reactivity, but it is currently unknown whether these changes are driven by downstream events that lead to force development, specifically, Ca2+‐regulated activation of
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::7231c5b745c2dff58469b3da553a872f
https://pubmed.ncbi.nlm.nih.gov/30592188
https://pubmed.ncbi.nlm.nih.gov/30592188
Publikováno v:
Physiological Reports
In this study, we investigated the quantitative and qualitative role of the sarcoplasmic reticulum (SR) in the regulation of the force‐frequency relationship (FFR). We blocked the function of SR with cyclopiazonic acid (CPA) and ryanodine and measu
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2d4129d9ae85a807e791fb937b6fce06
https://pubmed.ncbi.nlm.nih.gov/30350481
https://pubmed.ncbi.nlm.nih.gov/30350481