Zobrazeno 1 - 10
of 119
pro vyhledávání: '"muscle connective tissue"'
Autor:
Chengzhu Zhao, Makoto Ikeya
Publikováno v:
Frontiers in Cell and Developmental Biology, Vol 12 (2024)
Fibro/adipogenic progenitors (FAPs) that reside in muscle tissue are crucial for muscular homeostasis and regeneration as they secrete signaling molecules and components of the extracellular matrix. During injury or disease, FAPs differentiate into d
Externí odkaz:
https://doaj.org/article/01dc4e49159d4b23aa69dd8bb338f738
Akademický článek
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Autor:
Jagdeep Nanchahal, Catherine Ball, Jennifer Swettenham, Susan Dutton, Vicki Barber, Joanna Black, Bethan Copsey, Melina Dritsaki, Peter Taylor, Alastair Gray, Marc Feldmann, Sarah Lamb
Publikováno v:
Wellcome Open Research, Vol 2 (2017)
Dupuytren’s disease is a common fibrotic condition of the hand affecting 4% of the population and causes the fingers to curl irreversibly into the palm. It has a strong familial tendency, there is no approved treatment for early stage disease, and
Externí odkaz:
https://doaj.org/article/ee1feca57c3e4f009e4f0bef85aaaabb
Autor:
David Grahame Hardie, Sheng-Cai Lin
Publikováno v:
F1000Research, Vol 6 (2017)
Orthologues of AMP-activated protein kinase (AMPK) occur in essentially all eukaryotes as heterotrimeric complexes comprising catalytic α subunits and regulatory β and γ subunits. The canonical role of AMPK is as an energy sensor, monitoring level
Externí odkaz:
https://doaj.org/article/dcc7cedcef2c4de4a55850bfa10eafea
Publikováno v:
F1000Research, Vol 6 (2017)
The centrosome is an unusual organelle that lacks a surrounding membrane, raising the question of what limits its size and shape. Moreover, while electron microscopy (EM) has provided a detailed view of centriole architecture, there has been limited
Externí odkaz:
https://doaj.org/article/77a4edf13a9a47d4942b3b12c842471a
Autor:
Yin Hua Zhang
Publikováno v:
F1000Research, Vol 6 (2017)
Nitric oxide (NO) is an imperative regulator of the cardiovascular system and is a critical mechanism in preventing the pathogenesis and progression of the diseased heart. The scenario of bioavailable NO in the myocardium is complex: 1) NO is derived
Externí odkaz:
https://doaj.org/article/39c61f2aaf914c2d8d93a7b255461de7
Autor:
Seiji Fukumoto, Toshio Matsumoto
Publikováno v:
F1000Research, Vol 6 (2017)
There has been substantial progress in the management of patients with osteoporosis and the prevention of osteoporotic fractures. Currently available strong anti-resorptive agents are bisphosphonates and an anti-receptor activator of nuclear factor-k
Externí odkaz:
https://doaj.org/article/1d47858af25347a69dde3e6f89813bc5
Autor:
Pamela G. Robey
Publikováno v:
F1000Research, Vol 6 (2017)
The concept of a post-natal “mesenchymal stem cell” (“MSC”) originated from studies focused on bone marrow stromal cells (BMSCs), which are non-hematopoietic adherent cells, a subset of which are skeletal stem cells (SSCs), able to form carti
Externí odkaz:
https://doaj.org/article/869a6a50579645c89869cf306a24ac66
Publikováno v:
F1000Research, Vol 6 (2017)
For decades, researchers have been fascinated by the strategy of using cell therapy for bone defects; some progress in the field has been made. Owing to its ample supply and easy access, skin, the largest organ in the body, has gained attention as a
Externí odkaz:
https://doaj.org/article/cf40c5fa2aa8478ba6939b33f2c0b87d
Publikováno v:
F1000Research, Vol 6 (2017)
Adult muscle stem cells, originally called satellite cells, are essential for muscle repair and regeneration throughout life. Besides a gradual loss of mass and function, muscle aging is characterized by a decline in the repair capacity, which blunts
Externí odkaz:
https://doaj.org/article/b4365f1f26a04b96b1577a8464c5a08f