Zobrazeno 1 - 10
of 1 086
pro vyhledávání: '"multidrug efflux pump"'
Autor:
Shaya Alimoghadam, Arvin Eslami, Rojina Alimoghadam, Ibrahim Bahrami Mianrood, Mehdi Azizmohammad Looha, Sanaz Khodadadi, Shervin Shokouhi, Ilad Alavi Darazam
Publikováno v:
Journal of Global Antimicrobial Resistance, Vol 39, Iss , Pp 159-169 (2024)
Objectives: Pseudomonas aeruginosa is a major opportunistic pathogen responsible for a wide range of infections. The emergence of antibiotic resistance in this pathogen poses a significant public health challenge. This study aims to conduct a compreh
Externí odkaz:
https://doaj.org/article/f9d921794b7e4468af031202d36ba80e
Publikováno v:
Frontiers in Microbiology, Vol 15 (2024)
The worldwide spread of Pseudomonas aeruginosa, especially carbapenem-resistant P. aeruginosa (CRPA), poses a serious threat to global public health. In this research, we collected and studied the clinical prevalence, molecular epidemiology, and resi
Externí odkaz:
https://doaj.org/article/852a0daa5a184c07ae2945e57d6ef0ae
Publikováno v:
Virulence, Vol 15, Iss 1 (2024)
Salmonella enterica serovar Typhi (S. Typhi) causes typhoid fever, a systemic infection that affects millions of people worldwide. S. Typhi can invade and survive within host cells, such as intestinal epithelial cells and macrophages, by modulating t
Externí odkaz:
https://doaj.org/article/7150bf028b034ababce1151df82f5df4
Autor:
Rawaf Alenazy
Publikováno v:
Journal of King Saud University: Science, Vol 36, Iss 4, Pp 103116- (2024)
The infections of multidrug-resistant bacteria, particularly the infections caused by Gram-negative bacterial infections, are considered the main global serious health problems. Multidrug-resistant bacteria possess different resistance mechanisms, th
Externí odkaz:
https://doaj.org/article/8811efaf589a4aa68dc6bce58553c872
Publikováno v:
Medicine in Drug Discovery, Vol 20, Iss , Pp 100164- (2023)
Multidrug resistance (MDR) poses a severe threat to human health. The existence of efflux pumps primarily contributes to resistance in Gram-negative bacterial infections. Efflux pump inhibitors (EPIs) can potentially improve the efficacy of antibioti
Externí odkaz:
https://doaj.org/article/24ed83f1e1454130a238b95b3610546d
Publikováno v:
mSphere, Vol 8, Iss 5 (2023)
ABSTRACT Efflux and motility are two key biological functions in bacteria. Recent findings have shown that efflux impacts flagellum biosynthesis and motility in Escherichia coli and other bacteria. AcrR is known to be the major transcriptional repres
Externí odkaz:
https://doaj.org/article/8bb8d9a1e304444e8fb2771e1c875fd8
Autor:
Wedad M. Nageeb, Nada AlHarbi, Amani A. Alrehaili, Shadi A. Zakai, Ahmed Elfadadny, Helal F. Hetta
Publikováno v:
Frontiers in Microbiology, Vol 14 (2023)
IntroductionAlthough carbapenemases are frequently reported in resistant A. baumannii clinical isolates, other chromosomally mediated elements of resistance that are considered essential are frequently underestimated. Having a wide substrate range, m
Externí odkaz:
https://doaj.org/article/594fc1d0988f4528b01b16e6710881e7
Autor:
Zhemin Zhang, Nicholas Lizer, Zuowei Wu, Christopher E. Morgan, Yuqi Yan, Qijing Zhang, Edward W. Yu
Publikováno v:
Microbiology Spectrum, Vol 11, Iss 4 (2023)
ABSTRACT Campylobacter jejuni is a bacterium that is commonly present in the intestinal tracts of animals. It is also a major foodborne pathogen that causes gastroenteritis in humans. The most predominant and clinically important multidrug efflux sys
Externí odkaz:
https://doaj.org/article/700874412bb6467ea83f6d28db7b91ca
Publikováno v:
mBio, Vol 14, Iss 3 (2023)
ABSTRACT The continued challenges of the COVID-19 pandemic combined with the growing problem of antimicrobial-resistant bacterial infections has severely impacted global health. Specifically, the Gram-negative pathogen Klebsiella pneumoniae is one of
Externí odkaz:
https://doaj.org/article/f13fd0e9153c4ce5aa6dde24dead76f8
Publikováno v:
Antibiotics, Vol 12, Iss 9, p 1417 (2023)
The excessive use of antibiotics has led to the emergence of multidrug-resistant (MDR) pathogens in clinical settings and food-producing animals, posing significant challenges to clinical management and food control. Over the past few decades, the di
Externí odkaz:
https://doaj.org/article/1671c977b89f446686a51f4570b66da4