Zobrazeno 1 - 10
of 115
pro vyhledávání: '"multicellular aggregates"'
Akademický článek
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Autor:
Irène Nagle, Alain Richert, Michael Quinteros, Sébastien Janel, Edgar Buysschaert, Nathalie Luciani, Henry Debost, Véronique Thevenet, Claire Wilhelm, Céline Prunier, Frank Lafont, Teresita Padilla-Benavides, Mathieu Boissan, Myriam Reffay
Publikováno v:
Frontiers in Cell and Developmental Biology, Vol 10 (2022)
Epithelial–mesenchymal transition is associated with migration, invasion, and metastasis. The translation at the tissue scale of these changes has not yet been enlightened while being essential in the understanding of tumor progression. Thus, bioph
Externí odkaz:
https://doaj.org/article/d8c29659b2c04f68adaf872c5add5e7b
Autor:
Cândida Lucas, Coralie Silva
Publikováno v:
Frontiers in Bioscience-Elite, Vol 15, Iss 2, p 13 (2023)
Microbes are traditionally regarded as planktonic organisms, individual cells that live independently from each other. Although this is true, microbes in nature mostly live within large multi-species communities forming complex ecosystems. In these c
Externí odkaz:
https://doaj.org/article/7d326d68530c40aa874bc43fe18bb53f
Autor:
Dhiraj Indana, Ovijit Chaudhuri
Publikováno v:
eLife, Vol 10 (2021)
A new method for applying solid stress to aggregates of cells is shedding light on the impact of mechanical forces on cancer cells.
Externí odkaz:
https://doaj.org/article/fe8d1657b2fa40e9aa63fee767988d8a
Autor:
Monika E Dolega, Sylvain Monnier, Benjamin Brunel, Jean-François Joanny, Pierre Recho, Giovanni Cappello
Publikováno v:
eLife, Vol 10 (2021)
Imposed deformations play an important role in morphogenesis and tissue homeostasis, both in normal and pathological conditions. To perceive mechanical perturbations of different types and magnitudes, tissues need appropriate detectors, with a compli
Externí odkaz:
https://doaj.org/article/31ceeb51a910491db7ea54288098f188
Autor:
Christoph Mark, Thomas J Grundy, Pamela L Strissel, David Böhringer, Nadine Grummel, Richard Gerum, Julian Steinwachs, Carolin C Hack, Matthias W Beckmann, Markus Eckstein, Reiner Strick, Geraldine M O'Neill, Ben Fabry
Publikováno v:
eLife, Vol 9 (2020)
We describe a method for quantifying the contractile forces that tumor spheroids collectively exert on highly nonlinear three-dimensional collagen networks. While three-dimensional traction force microscopy for single cells in a nonlinear matrix is c
Externí odkaz:
https://doaj.org/article/445809e39596411894c241e66afcfafe
Publikováno v:
Toxics, Vol 9, Iss 2, p 24 (2021)
Seaweed bioactive compounds have shown anticancer activities in in vitro and in vivo studies. However, tests remain limited, with conflicting results, and effects in combination with anticancer drugs are even scarcer. Here, the cytotoxic effects of f
Externí odkaz:
https://doaj.org/article/fe699ff3869241b0806771b7a0398d0e
Autor:
S. G. Zakharov, A. K. Golenkov, T. A. Mitina, T. D. Lutskaya, K. A. Belousov, R. S. Fadeev, M. E. Solovieva, A. S. Senotov, V. S. Akatov
Publikováno v:
Alʹmanah Kliničeskoj Mediciny, Vol 1, Iss 31, Pp 11-16 (2016)
Background: Therapeutic efficiency in treatment of acute myeloid leukemia (AML) ranges from 20 to 45%. One of the causes of the latter is a drug resistance acquired by leukemic cells under the influence of treatment with antitumor medicines. More imp
Externí odkaz:
https://doaj.org/article/331728d5e38a491d803e9bb885a9cb27
Autor:
Yuliya Klymenko, Rebecca B. Wates, Holly Weiss-Bilka, Rachel Lombard, Yueying Liu, Leigh Campbell, Oleg Kim, Diane Wagner, Matthew J. Ravosa, M. Sharon Stack
Publikováno v:
Disease Models & Mechanisms, Vol 11, Iss 9 (2018)
Epithelial ovarian cancer (EOC) is the most lethal gynecological malignancy. EOC dissemination is predominantly via direct extension of cells and multicellular aggregates (MCAs) into the peritoneal cavity, which adhere to and induce retraction of per
Externí odkaz:
https://doaj.org/article/23d487ad0f98422286b48baec1cf41ef
Publikováno v:
International Journal of Molecular Sciences; Volume 23; Issue 23; Pages: 14637
The reactivating of disseminated dormant breast cancer cells in a soft viscoelastic matrix is mostly correlated with metastasis. Metastasis occurs due to rapid stress relaxation owing to matrix remodeling. Here, we demonstrate the possibility of prom