Development of a Multicellular 3D Tumor Model to Study Cellular Heterogeneity and Plasticity in NSCLC Tumor Microenvironment

Autor: Leena Arora, Moyna Kalia, Suman Dasgupta, Navneet Singh, Anita K. Verma, Durba Pal

Publikováno v: Frontiers in Oncology, Vol 12 (2022)

Heterogeneity is a characteristic feature of solid tumors. Intra-tumor heterogeneity includes phenotypic diversity, epigenetic abnormalities, cell proliferation, and plasticity that eventually drives disease progression. Studying tumor heterogeneity

Externí odkaz: https://doaj.org/article/1c785378ca8642c8922e3e6923cff6b5

In Vitro Characterization of Lu-177-DOTA-M5A Anti-Carcinoembryonic Antigen Humanized Antibody and HSP90 Inhibition for Potentiated Radioimmunotherapy of Colorectal Cancer

Autor: Mohajershojai, Tabassom, Jha, Preeti, Bostroem, Anna, Frejd, Fredrik Y., Yazaki, Paul J., Nestor, Marika

Carcinoembryonic antigen (CEA) is an antigen that is highly expressed in colorectal cancers and widely used as a tumor marker. I-131 and Y-90-radiolabeled anti-CEA monoclonal antibodies (mAbs) have previously been assessed for radioimmunotherapy in e

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=dedup_wf_001::6f367b53278b70e676dc8fce85c7b9b4
http://urn.kb.se/resolve?urn=urn:nbn:se:uu:diva-473961

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Advancements in 3D spheroid imaging: Optimised cryosectioning and immunostaining techniques.

Autor: Charlet-Faure C; Department of Biochemistry and Molecular Biology, University of Southern Denmark, Campusvej 55, Odense M DK-5230, Denmark.; Faculté des Sciences Site St Charles Aix Marseille Université, 3 place Victor Hugo, Marseille 13331, France., Thulesen AP; Department of Biochemistry and Molecular Biology, University of Southern Denmark, Campusvej 55, Odense M DK-5230, Denmark., Rogowska-Wrzesinska A; Department of Biochemistry and Molecular Biology, University of Southern Denmark, Campusvej 55, Odense M DK-5230, Denmark.

Publikováno v: MethodsX [MethodsX] 2023 Oct 06; Vol. 11, pp. 102415. Date of Electronic Publication: 2023 Oct 06 (Print Publication: 2023).