Zobrazeno 1 - 10
of 202
pro vyhledávání: '"multi-target drug"'
Publikováno v:
Biochemistry and Biophysics Reports, Vol 39, Iss , Pp 101781- (2024)
One of the current mainstream treatments for multiple myeloma (MM) is chemotherapy. However, due to the high clonal heterogeneity and genomic complexity of MM, single-target drugs have limited efficacy and are prone to drug resistance. Therefore, the
Externí odkaz:
https://doaj.org/article/1e53162919714bbda7d40a1be3237199
Autor:
Adel Alblihy
Publikováno v:
Frontiers in Pharmacology, Vol 15 (2024)
Ovarian cancer, often labeled a “silent killer,” remains one of the most compelling and challenging areas of cancer research. In 2019 alone, a staggering 222,240 new cases of ovarian cancer were reported, with nearly 14,170 lives tragically lost
Externí odkaz:
https://doaj.org/article/f0134f6d8c924c2eb9f9a23633173e31
Autor:
Elisabete Lima, Jorge Medeiros
Publikováno v:
Applied Sciences, Vol 14, Iss 9, p 3898 (2024)
Alzheimer’s disease (AD), a slowly progressive neurodegenerative disorder, is the main cause of dementia worldwide. However, currently, the approved drugs to combat AD are effective only in treating its symptoms. In fact, an efficacious treatment f
Externí odkaz:
https://doaj.org/article/c3e0e651a1e940908bd7c599fd4dedf4
Akademický článek
Tento výsledek nelze pro nepřihlášené uživatele zobrazit.
K zobrazení výsledku je třeba se přihlásit.
K zobrazení výsledku je třeba se přihlásit.
Akademický článek
Tento výsledek nelze pro nepřihlášené uživatele zobrazit.
K zobrazení výsledku je třeba se přihlásit.
K zobrazení výsledku je třeba se přihlásit.
Akademický článek
Tento výsledek nelze pro nepřihlášené uživatele zobrazit.
K zobrazení výsledku je třeba se přihlásit.
K zobrazení výsledku je třeba se přihlásit.
Autor:
Hossein Haghaei, Somaieh Soltani, Seyedrafie Aref Hosseini, Mohammad Reza Rashidi, Saeed Karima
Publikováno v:
Pharmaceutical Sciences, Vol 27, Iss 1, Pp 14-31 (2021)
Biological activity of Boswellia extract (BE) has been attributed to its main active ingredients; i.e. Boswellic acids (BAs). BE/BAs possess a promising therapeutic potential in neurodegenerative disorders; including Alzheimer's disease (AD). The mul
Externí odkaz:
https://doaj.org/article/7ae32d34db1d43dfa77bfeb80bc733bf
Publikováno v:
Journal of Ayurveda and Integrative Medicine, Vol 13, Iss 2, Pp 100557- (2022)
Background: The COVID-19 caused by severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) has emerged as a global pandemic claiming more than 6 million lives worldwide as of 16 March 2022. Till date, no medicine has been developed which is prov
Externí odkaz:
https://doaj.org/article/9dbbf66f99f34f1eb9c0ac143b9a8e5c
Publikováno v:
Diagnostics, Vol 12, Iss 12, p 2975 (2022)
Alzheimer’s disease (AD) is a polygenic multifactorial neurodegenerative disease that, after decades of research and development, is still without a cure. There are some symptomatic treatments to manage the psychological symptoms but none of these
Externí odkaz:
https://doaj.org/article/91335ae803624a00a1e45d251811d17b
Publikováno v:
Frontiers in Chemistry, Vol 8 (2020)
With the rapid development of systems-based pharmacology and poly-pharmacology, method development for rational design of multi-target drugs has becoming urgent. In this paper, we present the first de novo multi-target drug design program LigBuilder
Externí odkaz:
https://doaj.org/article/9c7abdfd3b8444d0adcf5909b9a2d2a8