Zobrazeno 1 - 10
of 1 056
pro vyhledávání: '"multi-omics data"'
Publikováno v:
BMC Medical Informatics and Decision Making, Vol 24, Iss 1, Pp 1-14 (2024)
Abstract Background Predictive modeling based on multi-omics data, which incorporates several types of omics data for the same patients, has shown potential to outperform single-omics predictive modeling. Most research in this domain focuses on incor
Externí odkaz:
https://doaj.org/article/8c88fb2b71bb45a5900d58b5e3b59e83
Autor:
Zihe Ding, Xiaoyue Wang, Yi Zhang, Jian Liu, Lei Wan, Tao Li, Lin Chen, Na Lin, Yanqiong Zhang
Publikováno v:
Engineering, Vol 39, Iss , Pp 166-179 (2024)
Rheumatoid arthritis (RA), a globally increasing autoimmune disorder, is associated with increased disability rates due to the disruption of iron metabolism. Tripterygium glycoside tablets (TGTs), a Tripterygium wilfordii Hook. f. (TwHF)-based therap
Externí odkaz:
https://doaj.org/article/ce71fc7b0d474de8a53820e48d5bc0a5
Publikováno v:
Discover Oncology, Vol 15, Iss 1, Pp 1-10 (2024)
Abstract Colorectal cancer is one of the most common cancers around the world, which is a severe threat to people’s health. SMAD4 belongs to the dwarfin/SMAD family, which plays a crucial role in TGF-β and BMP signal pathways. As the molecular cha
Externí odkaz:
https://doaj.org/article/b03ecd5bbd0b4e9d9fbc6e737bd6142b
Publikováno v:
Journal of Cheminformatics, Vol 16, Iss 1, Pp 1-12 (2024)
Abstract Motivation Computational techniques for drug-disease prediction are essential in enhancing drug discovery and repositioning. While many methods utilize multimodal networks from various biological databases, few integrate comprehensive multi-
Externí odkaz:
https://doaj.org/article/d6551e4582384ec6bf08a983ed7fe1bc
Publikováno v:
Computational and Structural Biotechnology Journal, Vol 23, Iss , Pp 2507-2515 (2024)
The incidence of early-onset colorectal cancer (EOCRC) has increased significantly worldwide. Uncovering biomarkers that are unique to EOCRC is of great importance to facilitate the prevention and detection of this growing cancer subtype. Although ef
Externí odkaz:
https://doaj.org/article/dcc0958b88474c11aeb05b8bcec8ed69
Autor:
Sonya Neto, Andreia Reis, Miguel Pinheiro, Margarida Ferreira, Vasco Neves, Teresa Costa Castanho, Nadine Santos, Ana João Rodrigues, Nuno Sousa, Manuel A. S. Santos, Gabriela R. Moura
Publikováno v:
Human Genomics, Vol 18, Iss 1, Pp 1-16 (2024)
Abstract Background Aging represents a significant risk factor for the occurrence of cerebral small vessel disease, associated with white matter (WM) lesions, and to age-related cognitive alterations, though the precise mechanisms remain largely unkn
Externí odkaz:
https://doaj.org/article/2e0c7763ac12478f9c1753c74e574d65
Autor:
Keanning Li, Bingxing An, Mang Liang, Tianpeng Chang, Tianyu Deng, Lili Du, Sheng Cao, Yueying Du, Hongyan Li, Lingyang Xu, Lupei Zhang, Xue Gao, Junya LI, Huijiang Gao
Publikováno v:
Journal of Integrative Agriculture, Vol 23, Iss 5, Pp 1634-1643 (2024)
Presently, integrating multi-omics information into a prediction model has become a ameliorate strategy for genomic selection to improve genomic prediction accuracy. Here, we set the genomic and transcriptomic data as the training population data, us
Externí odkaz:
https://doaj.org/article/174d1302262e4897b4aa7669990028b7
Autor:
Carina R. Hartmann, Robin Khan, Jennifer Schöning, Maximilian Richter, Maike Willers, Sabine Pirr, Julia Heckmann, Johannes Dirks, Henner Morbach, Monika Konrad, Elena Fries, Magdalene Winkler, Johanna Büchel, Silvia Seidenspinner, Jonas Fischer, Claudia Vollmuth, Martin Meinhardt, Janina Marissen, Mirco Schmolke, Sibylle Haid, Thomas Pietschmann, Simone Backes, Lars Dölken, Ulrike Löber, Thomas Keil, Peter U. Heuschmann, Achim Wöckel, Sagar, Thomas Ulas, Sofia K. Forslund-Startceva, Christoph Härtel, Dorothee Viemann
Publikováno v:
Frontiers in Immunology, Vol 15 (2024)
IntroductionRespiratory viral infections (RVIs) are a major global contributor to morbidity and mortality. The susceptibility and outcome of RVIs are strongly age-dependent and show considerable inter-population differences, pointing to genetically a
Externí odkaz:
https://doaj.org/article/9f360bbb7f334dfd8f295291a1345444
Publikováno v:
Frontiers in Genetics, Vol 15 (2024)
Introduction: Developing effective breast cancer survival prediction models is critical to breast cancer prognosis. With the widespread use of next-generation sequencing technologies, numerous studies have focused on survival prediction. However, pre
Externí odkaz:
https://doaj.org/article/78358031f5624730856756e17283bac3
Publikováno v:
BMC Bioinformatics, Vol 25, Iss 1, Pp 1-19 (2024)
Abstract Background Classifying breast cancer subtypes is crucial for clinical diagnosis and treatment. However, the early symptoms of breast cancer may not be apparent. Rapid advances in high-throughput sequencing technology have led to generating l
Externí odkaz:
https://doaj.org/article/a11e095a40ec426d8ff9efa446064402