Zobrazeno 1 - 10
of 109
pro vyhledávání: '"multi-drug resistance protein"'
Autor:
Julien De Greef, Mathilde Akue, Nadtha Panin, Kévin-Alexandre Delongie, Marina André, Gwenaëlle Mahieu, Emilia Hoste, Laure Elens, Leïla Belkhir, Vincent Haufroid
Publikováno v:
Scientific Reports, Vol 14, Iss 1, Pp 1-9 (2024)
Abstract Bictegravir, a key second-generation integrase strand transfer inhibitor in the treatment of HIV, is subject to active efflux transport mediated by ABCB1 (P-glycoprotein). Several coding variants of ABCB1 have been described and associated w
Externí odkaz:
https://doaj.org/article/673a1d72024c4c09bb675d1b896f6a08
Akademický článek
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Publikováno v:
Malaria Journal, Vol 21, Iss 1, Pp 1-8 (2022)
Abstract Background Malaria chemoprophylaxis using chloroquine (CQ) and primaquine (PQ) has been administered to resident soldiers in the 3rd Army of Republic of Korea (ROK) to prevent malaria infection since the year 1997. Due to mass chemoprophylax
Externí odkaz:
https://doaj.org/article/d3d4f02d5f7c4411b1ac70751ba994fe
Autor:
Fatemeh Mosafa, Farzin Hadizadeh, Faezeh Fathi, Zahra Eslami Nasab, Tahereh Pourzahed, Sayyed Mohammad Aboutorabzade, Razieh Ghodsi
Publikováno v:
Iranian Journal of Basic Medical Sciences, Vol 24, Iss 6, Pp 815-824 (2021)
Objective(s): A new series of quinoline analogs of ketoprofen was designed and synthesized as multidrug resistance protein 2 (MRP2) inhibitors using ketoprofen as the lead compounds.Materials and Methods: The cytotoxic activity of the compounds was e
Externí odkaz:
https://doaj.org/article/211eec3f7e594244b3545c4b6ca81baf
Publikováno v:
Di-san junyi daxue xuebao, Vol 43, Iss 10, Pp 938-945 (2021)
Objective To explore the effect of long noncoding RNA cancer susceptibility 2 (lncRNA CASC2) on the sensitivity of glioma cells to temazolamide (TMZ) and investigate the underling mechanism. Methods Forty glioma tissue samples derived from the 40 pat
Externí odkaz:
https://doaj.org/article/d48287b536dc47de871d3774abbd181c
Autor:
Yanfei Wang, Yufen Xu, Ping Huang, Di Che, Zhouping Wang, Xijing Huang, Xiaofei Xie, Wei Li, Li Zhang, Xiaoqiong Gu
Publikováno v:
Frontiers in Genetics, Vol 12 (2021)
Background: Kawasaki disease (KD) is a systemic vasculitis in childhood, which mainly causes damage to coronary arteries, and intravenous immunoglobulin (IVIG) is the initial therapy. IVIG resistance increased risk of coronary complication in KD. And
Externí odkaz:
https://doaj.org/article/8015839a386746c7acfb2aa1dc7b39c6
Akademický článek
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Publikováno v:
Frontiers in Oncology, Vol 10 (2020)
Colorectal cancer (CRC) is one of the most fatal types of cancers that is seen in both men and women. CRC is the third most common type of cancer worldwide. Over the years, several drugs are developed for the treatment of CRC; however, patients with
Externí odkaz:
https://doaj.org/article/7fc054b5ff724f70ae33376c46be2be1
Publikováno v:
Journal of Functional Foods, Vol 12, Iss , Pp 262-270 (2015)
Chitosan oligosaccharides (COS) are functional foods with various biological activities. Acetaminophen (APAP) is a widely used antipyretic and analgesic drug that can cause acute liver injury when taken in overdose. To investigate the effects of COS
Externí odkaz:
https://doaj.org/article/7284682216454fef848781ba1e451ce8
Akademický článek
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