High-throughput platform for label-free sorting of 3D spheroids using deep learning

Autor: Claudia Sampaio da Silva, Julia Alicia Boos, Jonas Goldowsky, Manon Blache, Noa Schmid, Tim Heinemann, Christoph Netsch, Francesca Luongo, Stéphanie Boder-Pasche, Gilles Weder, Alba Pueyo Moliner, Roos-Anne Samsom, Ary Marsee, Kerstin Schneeberger, Ali Mirsaidi, Bart Spee, Thomas Valentin, Andreas Hierlemann, Vincent Revol

Publikováno v: Frontiers in Bioengineering and Biotechnology, Vol 12 (2024)

End-stage liver diseases have an increasing impact worldwide, exacerbated by the shortage of transplantable organs. Recognized as one of the promising solutions, tissue engineering aims at recreating functional tissues and organs in vitro. The integr

Externí odkaz: https://doaj.org/article/22da439e01c74baf80d340ea0048f0d2

Multi-drug-resistance efflux in cisplatin-naive and cisplatin-exposed A2780 ovarian cancer cells responds differently to cell culture dimensionality

Autor: Geoffrey Liu, Mariana Bleker de Oliveira, Sergey N. Krylov, Laurie Ailles, Vasilij Koshkin, Chun Peng, Allan Covens

Publikováno v: Molecular and Clinical Oncology

A primary reason for chemotherapy failure is chemoresistance, which is driven by various mechanisms. Multi-drug resistance (MDR) is one such mechanism that is responsible for drug extrusion from the intracellular space. MDR can be intrinsic and thus,

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::51f906e4afa756652ece11a238db809a
http://europepmc.org/articles/PMC8273925

Generation of a 3D model of osteosarcoma for the characterization of the effects of photon irradiation

Autor: Reichl, Julia

Das Osteosarkom ist ein primärer bösartiger Knochentumor, der durch maligne mesenchymale Zellen charakterisiert ist. Die Behandlung besteht normalerweise aus einer operativen Entfernung und einer Chemotherapie, selten wird eine Strahlentherapie ang

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=od_____10650::f977a911af1fa31df01173cd855042d3

Scaffold-free Tissue Formation Under Real and Simulated Microgravity Conditions

Autor: Johann Bauer, Ganna Aleshcheva, Ruth Hemmersbach, Lasse Slumstrup, Manfred Infanger, Markus Wehland, Daniela Grimm

Publikováno v: Aleshcheva, G, Bauer, J, Hemmersbach, R, Slumstrup, L, Wehland, M, Infanger, M & Grimm, D 2016, ' Scaffold-free Tissue Formation under Real and Simulated Microgravity Conditions ', Basic & Clinical Pharmacology & Toxicology . https://doi.org/10.1111/bcpt.12561

Scaffold-free tissue formation in microgravity is a new method in regenerative medicine and an important topic in Space Medicine. In this MiniReview, we focus on recent findings in the field of tissue engineering that were observed by exposing cells

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4ac003dda5948993c3a1e53c90289d51
https://doi.org/10.1111/bcpt.12561

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